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Biomedical subjects

Steven C Schachter

Publications and source records attributed to Steven C Schachter.

21 records · Page 2Linked to original sources

Current evidence indicates that antiepileptic drugs are anti-ictal, not antiepileptic.

Despite the large number of available drugs for epilepsy, the primary function of pharmacological therapy is the suppression of seizures, rather than the elimination of their underlying etiology, i.e. an antiepileptic effect. This paper suggests methods by which drugs could be tested for antiepileptic properties and reviews whether current antiepilectic drugs (AEDs) are antiepileptic in addition to being effective for seizure suppression.

Anticonvulsants↗

Vagus nerve stimulation: where are we?

Now nearly 5 years post-approval, vagus nerve stimulation has emerged as a major non-pharmacological treatment for epilepsy. The place of vagus nerve stimulation among antiepileptic drugs and other surgical therapies is still evolving. This review evaluates the role of vagus nerve stimulation in light of recently published research of its mechanism(s) of action, long-term efficacy, safety and tolerability, and application to other disorders besides epilepsy.

Animals↗