Cancer risks in BRCA1 carriers: time for the next generation of studies.
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Breast Neoplasms↗
Biomedical subjects
Stephen B Gruber
Publications and source records attributed to Stephen B Gruber.
Small changes in expression affect predisposition to tumorigenesis.
We have used quantitative measures of gene expression to show that constitutional 50% decreases in expression of one adenomatous polyposis coli tumor suppressor gene (APC) allele can lead to the development of familial adenomatous polyposis.
Adenoma↗