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Biomedical subjects

Soichiro Miyazaki

Publications and source records attributed to Soichiro Miyazaki.

8 recordsLinked to original sources

Evaluation of type 3 portable monitoring in unattended home setting for suspected sleep apnea: factors that may affect its accuracy.

OBJECTIVE: This study evaluates the reliability of type 3 portable monitoring (PM) in a home setting. STUDY DESIGN AND SETTING: Prospective study in sleep laboratory. Type 3 device (Stardust II) was evaluated in comparison with standard polysomnography (PSG) among patients with obstructive sleep apnea. Quality of recorded data and agreement between PM and PSG results were evaluated. RESULTS: Low quality of recorded data was observed only in 5 cases. Pattern of disordered breathing was recognized correctly by PM. Apnea/hypopnea index (AHI) correlated well with a mean bias of 3.7 +/- 13.1/h. High sensitivity of PM was observed generally, whereas specificity was lower in mild patients. AHI, record time, and sleep position were found to be the main factors that would affect the accuracy of PM. CONCLUSION: Type 3 PM is feasible in unattended home-setting for routine examination. Influence of the factors above should be comprehensively considered especially for mild patients.

Adult↗

A preliminary study on application of portable monitoring for diagnosis of obstructive sleep apnea.

Portable monitoring (PM) for diagnosis of obstructive sleep apnea has developed recently. Many studies were performed in the laboratory setting, with simultaneous polysomnographic recordings or required technical assistance in the home setting. And the data were automatically analyzed. In this study, we attempted to evaluate whether PM could be useful in fully unattended home setting, and whether the auto analysis of the data is reliable. Home setting examination by Stardust II, a novel PM device, was performed unattendedly on consecutive 62 patients who complained of snoring. The questionnaire survey on the difficulty of fitting and operation, and the discomfort was conducted by visual analog scale. Automatically and manually analyzed results were compared. The examination was successfully performed by all subjects. The difficulty of fitting and operation, and the discomfort were 2.9+/-1.9, 1.8+/-1.2 and 3.6+/-2.1, respectively. Auto analysis differed significantly from manual analysis not only in apnea/hypopnea index (AHI), but also in the construction of sleep disordered respiratory events. Although AHI in automatic and manual analysis had a good correlation (r=0.949; P<0.001), their agreement was poor, especially in mild and moderate cases. However, setting AHI=50 as a cut-off point in auto analysis, sensitivity and specificity could reach 100% and 92.5%, respectively. Accordingly, PM is useful to identify obstructive sleep apnea in an unattended home setting condition. Considering the significant difference between automatic and manual analysis, we suggest that the data analysis should be performed manually.

Adolescent↗

Maxillary cancer in a child: a case report.

Cases with maxillary cancer are most frequently found in the 5th to the 7th decades of life, and then rarely occur in adolescence, even less so in a children. One does not expect to encounter this tumor in children, considering that most have a non-epithelial origin. However, we had a case of maxillary squamous cell carcinoma which appeared in a 12-year-old boy. He was initially considered to have sinusitis, and received conservative treatment for a while. After diagnosis, a combination therapy consisting of preoperative irradiation along intra-arterial administration of 5-FU and CBDCA was followed by total maxillectomy and primary reconstruction. Unfortunately about 2 months later, distant metastasis developed along with local recurrence, and the boy died about 1 year 6 months after the initial presentation. The clinical details of this rare case will be discussed in conjunction with some important considerations in dealing with this type of malignancy in a child.

Carcinoma, Squamous Cell↗

Using an air-pad sensor for the diagnosis of sleep apnea: a trial study.

An air-pad sensor (APS) was developed to record respiratory effort non-invasively. The APS is placed under the subjects' bodies and acoustic signals received by the pad are analysed. Nine patients with obstructive sleep apnea (OSA) and two healthy subjects were examined using an APS and daytime polysomnography, including intraesophageal pressure (Peso), simultaneously. The agreement ratio in terms of the central apnea time between the APS and the Peso was 93.4%, although the ratio between the Peso and an abdominal strain gauge was 40.7%. The agreement ratio in terms of respiratory rate among the Peso, APS, and abdominal strain gauge in patients with OSA was high; but the agreement ratio was low (74.4%) between the Peso and the strain gauge in mixed apnea.

Adult↗

Facial pattern categories of sleep breathing-disordered children using Ricketts analysis.

The facial patterns of 29 children under the age of 15 years with tonsil and/or adenoid and sleep disorder problems was analysed. The lateral-cephalograms of these patients was digitized in a zero-based computer program using Ricketts analysis to examine facial patterns. Results of the analysis were compared with the mean of the control group, n = 41 (9-year-old Japanese children). There were significant differences (P < 0.01-0.001) between the patient group and the control group when comparing the facial axis, lower facial height, mandibular arc, total facial height, and McNamara-Pogonion. The facial pattern of children with sleep breathing disorders was discovered to be the dolico facial pattern.

Adolescent↗

Effectiveness of a tongue-retaining device.

The effectiveness of a tongue-retaining device (TRD) was examined at the baseline without any TRD [TRD(-)] and then with a TRD [TRD(+)] in eight patients with obstructive sleep apnea (OSA). In terms of the 3+ % oxygen desaturation index (ODI3), lowest percutaneous oxygen saturation (SpO2), and time spent SpO2 < 90%, there were significant differences (P < 0.01-0.05) between the findings for TRD(-) and TRD(+). The ODI3 dropped below the baseline by more than 50% in five patients (63%) and dropped to fewer than 10 events/ h in six patients (75%). The results indicate that oral appliances help patients with mild to moderate OSA; however, patients with more severe OSA may also be treated effectively with a TRD.

Activator Appliances↗