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Biomedical subjects

Simon Baker

Publications and source records attributed to Simon Baker.

5 recordsLinked to original sources

Breast cancer screening for women aged 40 to 49 years--what does the evidence mean for New Zealand?

AIM: To review the evidence on the benefits, harms and costs of breast cancer screening for women aged 40 to 49 years in New Zealand. METHODS: A review of the two most recently published meta-analyses of breast cancer screening, combined with a web-based literature search and review. RESULTS: The meta-analyses demonstrated that mammography reduces breast cancer mortality among women aged 40 to 74 years. Benefit is greatest, and harms are lowest, for women aged over 50. Cost-effectiveness is also greater for women aged over 50. CONCLUSION: The risks of developing and dying of breast cancer are continuous variables that increase with age. The United Kingdom Age Trial will provide further important evidence to guide policy on breast screening for women aged 40 to 49. The most recent reports of this trial suggest a smaller reduction in predicted deaths than observed in many other studies that included women below the age of 50, and less than in either of the meta-analyses reported in this article. Any further lowering of the age range of BSA should be informed by the results of this trial as well as other high quality studies that examine both the benefits and harms of breast screening for women aged 40 to 44.

Adult↗

What is the most appropriate breast-cancer screening interval for women aged 45 to 49 years in New Zealand?

AIM: To review the international evidence on the benefits and harms of different screening intervals for women aged 45 to 49 years, and to inform the development of a national policy. METHODS: A systematic search and review of the literature, up to March 2005. RESULTS: There is no robust trial evidence on which to base a decision on the most appropriate breast-cancer screening interval for women aged 45 to 49 years, and it is unlikely that definitive trial evidence will ever emerge. Evidence from less robust studies is equivocal. CONCLUSION: In the absence of definitive evidence, those charged with determining the screening interval for women aged 45 to 49 years in a breast-cancer screening programme have to weigh up the available evidence, and consider it alongside other relevant factors. A two-yearly screening interval for women aged 45 to 49 was decided upon, and became policy in New Zealand.

Age Factors↗

Appearance-based face recognition and light-fields.

Arguably the most important decision to be made when developing an object recognition algorithm is selecting the scene measurements or features on which to base the algorithm. In appearance-based object recognition, the features are chosen to be the pixel intensity values in an image of the object. These pixel intensities correspond directly to the radiance of light emitted from the object along certain rays in space. The set of all such radiance values over all possible rays is known as the plenoptic function or light-field. In this paper, we develop a theory of appearance-based object recognition from light-fields. This theory leads directly to an algorithm for face recognition across pose that uses as many images of the face as are available, from one upwards. All of the pixels, whichever image they come from, are treated equally and used to estimate the (eigen) light-field of the object. The eigen light-field is then used as the set of features on which to base recognition, analogously to how the pixel intensities are used in appearance-based face and object recognition.

Algorithms↗

Automatic construction of active appearance models as an image coding problem.

The automatic construction of Active Appearance Models (AAMs) is usually posed as finding the location of the base mesh vertices in the input training images. In this paper, we repose the problem as an energy-minimizing image coding problem and propose an efficient gradient-descent algorithm to solve it.

Algorithms↗