Biomedical subjects

Shingo Ikeda

Publications and source records attributed to Shingo Ikeda.

6 recordsLinked to original sources

PubMed2005

Site-selective direct photochemical deposition of copper on glass substrates using TiO2 nanocrystals.

Deposition of copper thin films was achieved by a photocatalytic reaction of site-selectively adsorbed TiO(2) nanocrystals for direct fabrication of copper circuit patterns on glass substrates. The nanocrystal monolayers absorbed on hydrophobic surface templates serve as an effective photocatalyst, producing metallic copper and formic acid via oxidation of methanol in solution. The formic acid generated has also been suggested to serve as an electron donor that accelerates copper deposition through a UV-mediated autocatalytic reaction, even after nanocrystals are embedded into the grown copper films. The thickness of the deposited copper films was easily controlled by varying the UV irradiation time, irradiation power, and initial concentration of methanol as a hole scavenger. The process presented herein provides an effective methodology for resist-free, direct metallization of insulating substrates.

Letter↗

PubMed2005

Controlling interparticle spacing among metal nanoparticles through metal-catalyzed decomposition of surrounding polymer matrix.

Systematic and reproducible control over average interparticle spacing of Pt, Ni, and Cu nanoparticles embedded in polyimide thin layers was achieved. The metal-catalyzed decomposition of polyimide matrixes surrounding metal nanoparticles causes a decrease in the composite layer thickness, while maintaining the size of nanoparticles. This ability provides an effective methodology for the preparation of metal/polymer nanocomposites with tailored microstructures and holds great promise toward the fundamental understanding of the physical interactions among metal nanoparticles.

Journal Article↗

PubMed2005

Pulmonary blastoma.

We describe a resected pulmonary blastoma in an 84-year-old male, the oldest of previously reported patients. A chest X-ray showed a 2 cm-sized abnormal shadow in the left lung field. Five months later computed tomography demonstrated a well-demarcated heterogenous mass, measuring 12 cm in diameter, in the left lower lobe of the lung. This mass was diagnosed as a carcinoma using echo-guided percutaneous biopsy. The patient underwent a left lower lobectomy. The resected specimen revealed the tumor to be a pulmonary blastoma arising from lung tissue. Preoperative diagnosis of pulmonary blastoma is extremely difficult because of the histological heterogeneity of tumor. Since it has been noted that pulmonary blastoma rapidly progresses in a short period of time, surgical treatment should be undertaken as quickly as possible when such a tumor is suspected.

Aged↗

PubMed2005

[Respiratory rehabilitation in elderly patients after surgical treatment in the thoracic region].

Respiratory rehabilitation is performed by a team of physicians, nurses, physiotherapists (respiratory therapists), nutritionists, and pharmacists together with the patient's family if necessary. In elderly patients, in whom chronic obstructive pulmonary disease (COPD) is often complicated before and after surgery, it is necessary to start respiratory physiotherapy and kinesiotherapy as the major therapies of respiratory rehabilitation in the early stage after surgery. Postoperative control of the amount of sputum, and recovery and maintenance of ventilatory gas exchange become possible by early respiratory rehabilitation, leading to prevention of complications, recovery of activities of daily living (ADL), and early discharge from hospital.

Aged↗

PubMed2004

Direct patterning of copper on polyimide using ion exchangeable surface templates generated by site-selective surface modification.

We demonstrate site-selective chemical surface modification by dispensing potassium hydroxide solution onto polyimide, which confines source metallic ions that can subsequently be used in resist- and mask-free fabrication of copper circuit patterns. Metallization can be achieved by a wet chemical method, providing control over metal/polymer interfacial structures. Because the approach is compatible with other existing printing technologies and much simpler than conventional lithography-based methods, we propose that the present surface template method may be of general application in fabrication of metallized polymers as well as in development of integrated circuits with a variety of electronic circuit elements.

Journal Article↗

PubMed2002

Micrometastasis to lymph nodes in stage I left lung cancer patients.

BACKGROUND: To evaluate the frequency and clinicopathological characteristics of lymph node micrometastasis in left lung cancer patients diagnosed to be stage IA and IB based on routine histopathologic examinations, we examined the lymph nodes in patients who had undergone an extended mediastinal lymphadenectomy, using immunohistochemical methods. METHODS: Paraffin-embedded tissue sections from the lymph nodes in 49 patients with stage I left lung cancers were studied. We used AE1/AE3 as the anticytokeratin and Ber-EP4 as the antiepithelial cell antibodies when performing immunohistochemical staining. RESULTS: We identified micrometastasis of the lymph nodes in 13 (26.5%) of 49 patients with stage I left lung cancer. NO disease was reclassified as N1 disease in 5 cases, N2 disease in 6 cases, and N3 disease in 2 cases. The location of the micrometastatic lymph nodes proved to be wide regions including the contralateral and highest mediastinal nodes, and 6 (46.2%) out of the 13 patients with micrometastasis were thus presumed not to be completely eliminated by a standard lymphadenectomy through an ipsilateral thoracotomy. The five year survival rate of patients with reclassified N1 to N3 disease was 74%, and the presence of micrometastasis was found to have no significant effect on the outcomes. CONCLUSIONS: The micrometastatic involvement of the lymph nodes was both more frequent and extensive than expected even in stage I left lung cancer. These results suggest that an extended mediastinal lymphadenectomy may therefore be required for the locoregional control of stage I left lung cancer patients.

Adenocarcinoma↗