Midgut abnormalities.
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Biomedical subjects
Publications and source records attributed to Scott C Boulanger.
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BACKGROUND: Pulmonary hypoplasia and hypertension are the primary causes of morbidity and mortality in infants with congenital diaphragmatic hernia (CDH). At present, the origin of CDH and the causes of pulmonary hypoplasia and hypertension are unknown. DATA SOURCES: This article reviews the available published data regarding the origin of CDH and the pathogenesis of the associated pulmonary hypertension and hypoplasia. These investigations have employed human tissues as well as two types of CDH animal models. CONCLUSIONS: Investigations performed to date have not yet provided definitive answers regarding the pathogenesis of CDH. However, they have yielded many new and exciting discoveries and several opportunities for intervention. Ongoing research should open new possibilities to improve the outcome for these unfortunate babies with CDH.
The authors report a case of an 11-year-old girl with a solitary, congenital pancreatic cyst and review the literature. Such cysts are very rare and typically are diagnosed in childhood. As a neonate, this patient's paternal half brother also had undergone resection of a congenital pancreatic cyst. The authors believe this is the first documented familial incidence of a congenital pancreatic cyst.
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INTRODUCTION: Giant intraabdominal cysts are very rare, and conventional treatment is full midline laparotomy. We present a case of complete laparoscopic extirpation of a giant ovarian cyst. CASE REPORT: A 16-year-old female presented with progressive abdominal distension for 1-year along with early satiety, constipation, and significant weight loss. A CT scan showed a giant multiseptated cystic mass in the abdomen measuring 22.5 x 30 x 40.5 cm with significant mass effect causing intrahepatic ductal dilatation and right hydronephrosis. The mass was decompressed via a mini-laparotomy in a controlled fashion, removing 15 liters of fluid. A laparoscopic left oophorectomy was then performed. The postoperative course was uneventful, and the patient was discharged home on postoperative day 1 with minimal pain and tolerating a regular diet. Pathology examination revealed a mature cystic teratoma. CONCLUSION: Giant ovarian cysts can be managed laparoscopically when a normal tumor marker profile and benign imaging appearance exclude the possibility of malignancy.