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Biomedical subjects

Sarah Shelton

Publications and source records attributed to Sarah Shelton.

3 recordsLinked to original sources

Characteristics and behaviors associated with body image in male domestic violence offenders.

Investigated correlates of body image satisfaction and perceived weight class (underweight, average weight, overweight) in a sample of male domestic violence offenders. Men who identified themselves as either underweight or overweight reported poorer body image satisfaction than those who perceived themselves to be of average weight. Poor body image satisfaction was found to be related to increased risk for both physical and verbal aggression, the tendency to have been a bully and/or a victim of bullying in childhood, and increased alcohol use. Although masculinity was expected to be an important intervening construct, partially explaining the relationship of body image to the major predictor variables, it was not correlated with any of the variables in this study. Finally, perceived weight class was not found to be significantly related to any of the predictor variables.

Journal Article↗

Relationship between team identification and trait aggression: a replication.

Research yielded no significant relationship between sport fandom and trait aggression. The current study replicated previous efforts using the Buss-Perry Aggression Questionnaire, an updated version of the Buss-Durkee Hostility Inventory. In contrast to past work, the current study did yield a significant relationship between fandom and aggression for men.

Adult↗

Atazanavir--a once-daily HIV protease inhibitor that does not cause dyslipidemia in newly treated patients: results from two randomized clinical trials.

Protease inhibitor (PI) treatment can result in dyslipidemia in a significant proportion of patients. Atazanavir (ATV) is a once-daily PI that has not been associated with clinically relevant increases in total cholesterol (TC), fasting low-density lipoprotein cholesterol (LDL-C), or fasting triglyceride (TG) concentrations. The objectives of this paper were to evaluate lipid profiles in untreated patients, and investigate the frequency and severity of dyslipidemia in the same individuals after treatment with ATV or nelfinavir (NFV) for 48 weeks. Two multinational, randomized, active-controlled, blinded trials compared the safety and efficacy of ATV and NFV in combination with two nucleoside reverse transcriptase inhibitors (NRTIs) in antiretroviral (ARV)-naive patients. Serum lipid concentrations were analyzed in patients who had available measurements both at baseline and at week 48. Patients who had missing data at either time point were not included. Lipid levels remained within baseline ranges at week 48 with ATV treatment, whereas clinically relevant elevations in TC, fasting LDL-C, and fasting TG concentrations occurred with NFV treatment. Mean changes from pre-treatment baseline in fasting LDL-C ranged from -6 percent to +6 percent in the ATV-treatment groups, and from +27 percent to +31 percent in the NFV-treatment groups. After 48 weeks, there was a substantive increase in the proportion of NFV-treated patients who would be recommended for lipid-lowering treatment by National Cholesterol Education Program (NCEP) guidelines, whereas a lesser proportion of ATV-treated patients would be recommended for lipid-lowering treatment. Atazanavir does not lead to dyslipidemia in ARV-naive patients, and may limit the need for lipid-lowering strategies to reduce the risk of cardiovascular disease.

Administration, Oral↗