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Biomedical subjects

Sarah Kuruvila

Publications and source records attributed to Sarah Kuruvila.

2 recordsLinked to original sources
PubMed2004

Bednar tumor.

Pigmented dermatofibrosarcoma protuberance DSFP, also known as Bednar tumor or formerly known as pigmented storiform neurofibroma is a rare variant of DSFP. Bednar first described it in 1957. The histology is striking because of the presence of multipolar pigment laden dendritic cells scattered among spindle shaped cells with a storiform pattern, the latter being characteristic of DSFP. The spindle cells are positive for CD34, and Vimentin and negative for S100. The pigment represents melanin. We describe such a tumor because of its rarity and very striking microscopic appearance.

Adult↗
PubMed2003

Uterine neoplasm resembling an ovarian sex cord tumor.

Uterine neoplasm resembling an ovarian sex cord tumor is a rare neoplasm. Patients are generally of reproductive age, although a few may be perimenopausal or post menopausal. This neoplasm produces abnormal vaginal bleeding and uterine enlargement, suggesting leiomyoma or polyps. Based on the histology and clinical outcome, this tumor can be classified into 2 groups, namely one with focal areas resembling sex cord elements with a tendency to recur or metastasize and another with exclusive sex cord elements which runs a benign course. Immunohistochemical stains of the sex cord elements may show positively for vimentin, cytokeratin, actin and desmin in variable proportions. Inhibin is a more specific marker for these cells. Our case was a 50-year- old Omani lady with menorrhagia. Histology revealed features consistent with uterine neoplasm resembling an ovarian sex cord tumor.

Female↗