Search PubMed⌕ Search

Biomedical subjects

Samuel R Dominguez

Publications and source records attributed to Samuel R Dominguez.

6 recordsLinked to original sources
PubMed2006

Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome.

We conducted a blinded, case-control, retrospective study in pediatric patients hospitalized at The Children's Hospital, Denver, Colorado, to determine whether human coronavirus (HCoV)-NL63 infection is associated with Kawasaki syndrome (KS). Over the course of a 7-month period, nasopharyngeal-wash samples from 2 (7.7%) of 26 consecutive children with KS and 4 (7.7%) of 52 matched control subjects tested positive for HCoV-NL63 by reverse transcription-polymerase chain reaction. These data suggest that, although HCoV-NL63 was circulating in children in our community during the time of the study, the prevalence of infection with HCoV-NL63 was not greater in patients with KS than in control subjects.

Case-Control Studies↗
PubMed2005

Physician knowledge and perspectives regarding influenza and influenza vaccination.

BACKGROUND: Recent studies have demonstrated that healthy children younger than 24 months of age are at risk for influenza-associated hospitalization and influenza related complications. In light of this, the American Academy of Pediatrics (AAP) and the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention changed their recommendation for influenza vaccination for the 2004-05 season to include universal vaccination for all healthy children 6-23 months of age. METHODS: A self-administered survey was distributed to a random sampling of family practitioners and pediatricians in Chicago, IL. Questions were asked regarding demographics, current use of influenza vaccines, and knowledge regarding influenza vaccines and influenza infection in children. Answers were scored as correct based on published literature and AAP/ACIP recommendations. RESULTS: During the 2002-2003 influenza season, recommendation for influenza vaccination and perceived use for both healthy children and children with a high-risk medical condition were both low. The majority of physicians were not aware of the severity of influenza infection in young children, could not correctly identify all contraindications to receiving vaccination, did not know which children require two vaccinations, and were not aware of the complications of influenza in children. CONCLUSIONS: To achieve the goal of universal influenza vaccination coverage for the 2004-05 season for healthy children 6-23 months of age, physicians will need a greater understanding of the severity of influenza illness in this age group coupled with an increased knowledge of indications for vaccine administration.

Adolescent↗
PubMed2004

Cellulitis.

Explore the source record for details and available documents.

Anti-Bacterial Agents↗
PubMed2004

On-time immunization rates among children who enter Chicago public schools.

OBJECTIVE: A primary objective of the Healthy People 2010 initiatives is to increase on-time immunization rates during the first 2 years of life and to decrease racial disparities in coverage. The objective of this study was to determine on-time immunization coverage rates among infants and toddlers stratified by race/ethnicity in a large metropolitan center. METHODS: A retrospective cohort study that was based on immunization records in the Chicago Public Schools computerized database was conducted using all 67376 children who completed kindergarten in 2001 and 2002. RESULTS: On-time immunization rates in Chicago public school children are low (31% at 7 months, 32% at 19 months, 59% at 36 months). At 19 months of age and thereafter, Hispanic children had the highest rate of on-time immunization coverage. Among children <48 months old, black children had the lowest rates of up-to-date immunization status. At 48 months of age, the up-to-date rate for black children improved to a rate similar to white children (58%) and by school entry surpassed the up-to-date rate for white children (71%). Compared with the recommended 2, 4, 6, and 15 to 18 months schedule, black children received 4 doses of diphtheria/tetanus/acellular pertussis at a mean age of 10.0, 14.6, 20.4, and 34.5 months of age. In contrast, Hispanic children received the same doses at a mean of 4.5, 7.4, 11.0, and 25.1 month of age. In addition, approximately 25% of black children received the majority of their vaccinations >12 months later than the recommended time intervals. CONCLUSIONS: Striking immunization delay still exists during the infant and toddler years. Targeted efforts are needed to increase on-time immunization rates and to decrease racial disparity in immunization coverage.

Chicago↗