Gift authorship practices -- history, trends and remedies.
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Biomedical subjects
Publications and source records attributed to Saba Sohail.
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Hemorrhagic corpus luteum (CL) is clinically known to simulate a number of medical, surgical and gynecologic conditions that cause acute abdomen. One such case is hereby presented that mimicked ectopic pregnancy clinically and heterotopic pregnancy on ultrasound. Laparoscopy was decisive.
OBJECTIVE: To determine the applicability of uterine biophysical profile (UBP) scoring with chances of pregnancy in a spontaneous cycle in a cohort of females with unexplained infertility. DESIGN: Observational study. PLACE AND DURATION OF STUDY: A secondary level private hospital, from June 2003 to June 2004. PATIENTS AND METHODS: The study subjects included 26 infertile females in the third decade of life primarily referred for follicle maturation monitoring by ultrasound with patent tubes and normal utero-ovarian morphology. Male factor infertility was also excluded. The UBP was determined by applying the uterine scoring system for reproduction (USSR). A score of 17 or above, out of a perfect score of 20, was hypothesized to be favorable for pregnancy. Frequency of pregnancy was correlated with the cumulative score as well as individual variable. Significance of correlation was taken at p<0.05. RESULTS: None of the patients showed a perfect score of 20. A score of 17 was noted in 06 patients out of whom 04 conceived (pregnancy rate=66.6%). A score of 15 or less was observed in 20 patients, none of whom conceived (p=0.001). No significant correlation was found with any of the individual variables including the endometrium and myometrium characteristics, as well as the uterine artery flow. Myometrium contraction was the most technically difficult parameter to be observed. CONCLUSION: In this small cohort of patients, an ultrasonographically assessed uterine score of 17 or above was significantly associated with chances of pregnancy in the similar spontaneous cycle.
OBJECTIVE: To determine the sensitivity of transvaginal ultrasound (TVUS) in the detection of vesicovaginal fistula (VVF). METHODS: The study included 15 patients with urinary incontinence suspected or diagnosed to be due to vesicovaginal fistula that were originally referred to the department for intravenous urography (IVU). Complimentary TVS was done with consent. Cases with stress incontinence and co-existent rectovaginal fistulae were excluded. Findings were compared against the cystogram, cystoscopy and surgical findings for determining the sensitivity, the last being taken as the gold standard. RESULTS: The fistula was visualized as a jet of echoes in real time from bladder to the vagina in all 15 cases. The location number and size corresponded with the surgical findings. The sensitivity of trans-vaginal scanning in diagnosing WF was 100%, that of cystoscopy- 93% and of cystography- 60%. CONCLUSION: In this series, the trans-vaginal scan findings correlated well with the surgical findings. It was less invasive and more tolerable than cystoscopy.
OBJECTIVE: To determine the variables, which affect pain tolerance in x-ray hysterosalpingography (HSG). DESIGN: Cross-sectional comparative study. PLACE AND DURATION OF STUDY: Radiology departments of Civil and Bismillah Taqee Hospitals and Delhi Mercantile Medical Centre, Karachi from January 1999 to June 2003. PATIENTS AND METHODS: The study included 250 patients who underwent x-ray HSG using small sized Leech Wilkinson cannula by the same radiologist. Informed verbal consent was obtained from all the patients. Pain was graded into tolerable and intolerable using a four-point visual analog scale (VAS) as well as the Pakistani coin scale after pre-medication with diclofenac (generic name). Standard procedures using day-light fluoroscopy was performed. Variables considered were age, indication of the procedure, type of infertility, whether primary or secondary, emotional state, motivation for investigation, presence or absence of cystocele, duration of procedure, type of contrast used, whether ionic or non-ionic, tubal patency and lastly the amount of contrast used in the procedure. Those patients having infection, cervical erosion, use of larger size of cannula and technical complications including excessive bleeding requiring the use of sanitary napkins and vascular intravasation were excluded. The obtained data was analyzed on SPSS version 10.0 using cross tabulation and Pearson's correlation coefficient. Significance was taken at p<0.05. RESULTS: The mean age of the patients was 30 years. Amenorrhea, secondary infertility, apprehension, prolonged procedure time (>15 minutes) and the use of ionic contrast media were the variables significantly associated with intolerable pain during the procedure. Primary infertility, calm emotional state, self-motivation, absence of cystocele and short procedure duration were associated with good pain tolerance. The amount of contrast used and tubal patency status had no significant association. CONCLUSION: In the setting of base line pre-medication with diclofenac and minimal cervical trauma, amenorrhea, primary infertility, emotional state, self-motivation, procedure duration, and the presence or absence of cystocele significantly affect pain tolerance during the procedure. Amount of contrast used and tubal patency does not affect pain tolerance. Effect of the type of contrast medium requires further confirmation on a larger number of patients.
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The case of a female child is described who presented with recurrent respiratory infections and "recurrent right subphrenic abscess." Detailed radiological work-up identified situs ambiguous abdominis with bronchiectasis, duodenal malrotation, umbilical hernia and spina bifida.
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