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Biomedical subjects

S el-Mahgoub

Publications and source records attributed to S el-Mahgoub.

15 recordsLinked to original sources
PubMed1980

Body weight and cycle control of injectable contraceptives.

Five long-acting progestogens were tried as injectable contraceptives in 1,363 women for one to three years. A total of 22,304 woman-months were studied. The first injection was given either within five days of the onset of the menstrual cycle or during the postpartum phase (330 women). The different factors that may influence cyclicity were analyzed. Among these factors, the following may be important: potency and dose of progestogen, addition of long-acting estrogen, pretreatment menstrual pattern, duration of therapy and body weight of users. The incidence of amenorrhea was higher in overweight than in underweight or normal subjects. The causal relationship can be explained by the storage of the absorbed progestogen in the adipose mass.

Adolescent↗
PubMed1978

Unification of a septate uterus: Mahgoub's operation.

A simple surgical technique for unification of a septate uterus is described. The septum and a small strip of fundus are removed with scissors inserted through two small fundal stabs, and the opening is closed with one mattress suture, which forms an anteroposterior suture line no more than 1 cm long. At the end of the operation an intrauterine contraceptive device is inserted to prevent uterine adhesions. The operation has several advantages: (a) it leaves a capacious uterine cavity of normal appearance, (b) it avoids large uterine incisions, and thus the possibility of postoperative adhesions or weak uterine scars, and (c) it avoids possible injury to the cornual ends of the Fallopian tubes. This article reports favorable results in 17 women treated with this surgical technique.

Abortion, Habitual↗
PubMed1971

Injected progestogen and lactation.

Norethisterone ethanate (200 mg every 84 days) and medroxyprogesterone acetate (150 mg every three months) were found to be completely effective in fertility control when started in the puerperium. Neither agent had any ill effect on the amount of milk or the duration of lactation. From the third month onward the three-hourly available milk and the infant weight gain per month were statistically higher in treated groups than in controls. Milk proteins showed a slight decrease in most groups, including the controls, owing to the low-protein diet.No important side effect was produced by these agents other than amenorrhoea.

Adult↗
PubMedDate not supplied

Galactorrhea and the defective luteal phase of the menstrual cycle.

Twelve patients with primary infertility due to a defective luteal phase associated with hyperprolactinemia and galactorrhea are reported. All were treated with 2-bromoergocryptine. During the first cycle of therapy, the serum prolactin level decreased in all cases, and galactorrhea disappeared during the second cycle of therapy. Seven women responded to 2-bromoergocryptine, as was reflected in their endometrial biopsies. The remaining five were given clomiphene citrate on the second and sixth days of the next 2-bromoergocryptine cycle. Three of these patients responded favorably to this combined therapy. Six pregnancies were reported during therapy. The results of follow-up after labor or abortion suggested that these cases represent a latent stage of the amenorrhea-galactorrhea syndrome.

Adult↗