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Biomedical subjects

S dal Forno

Publications and source records attributed to S dal Forno.

4 recordsLinked to original sources

Clinical-experimental research on aztreonam ampullar and ureteral concentrations.

After pointing out that, during urinary tract infections, bacteria can affect the peristalsis of the renal ampulla and of the ureter, the authors report the results of a trial on aztreonam concentrations in the upper urinary tract, performed in order to evaluate the concentrations of the drug in the ampullar and ureteral tissues. This study was carried out on bioptical specimens collected from 18 subjects (12 children and 6 adults), who underwent surgery for malformations of the urinary system. The authors report and discuss the results of the determinations performed on the samples of urinary tract tissue, serum and urine, 60 to 90 minutes after the i.m. administration of aztreonam.

Adolescent↗

Blind ureteric buds.

Four cases of blind ureteric bud are presented. This unusual abnormality is the result of abortive development of a normal bud or, more frequently, of an accessory bud brought into being by abnormal or premature division of the primary bud. - The disputed relationship between this abnormality and congenital ureteral and vescical diverticula is discussed. It is felt that the embryogenetic and anatomopathological evidence justifies the inclusion of some of the latter within the more extensive term "blind ureteric bud".

Child↗

Discontinuing medication in epileptic children: a study of risk factors related to recurrence.

We studied 70 children who had experienced at least two seizures before age 12 years, excluding febrile seizures, neonatal seizures, or seizures occurring during a metabolic, or infectious insult to the central nervous system (CNS) and who had been seizure free for at least 2 years. Twenty children (28.5%) experienced a recurrence, 75% during antiepileptic (AED) drug discontinuation or less than 6 months after discontinuation. Risk factors statistically related to seizure recurrence were greater than 10 seizures before seizure control, an abnormal EEG in the year before AED discontinuation, presence of focal neurologic signs and/or mental retardation, and presence of a mixed seizure pattern. Fourteen children (70%) with recurrence had two or more risk factors, whereas 36 (72%) without recurrence had no risk factor or only one. We conclude that a selected group of epileptic children who remain seizure-free for a period of at least 2 years can have AEDs discontinued based on presence or absence of risk factors.

Anticonvulsants↗

[Transitional cell neoplasm of the bladder in childhood: presentation of a clinical case].

A case of urothelial carcinoma of the bladder in a 13-year-old boy is reported. As observed in the literature, it is an extremely rare condition in children. The importance of gross or microscopic hematuria, which is often the only sign of this condition, is underscored. The authors comment on the possible follow-up modalities in relation with the characteristics of this tumor type in young patients. Although it is more invasive (anesthesia, trauma) than US or urinary cytology, cystoscopy is more precise. Because recurrence is extremely rare, it can be performed once a year.

Adolescent↗