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Biomedical subjects

S Zisook

Publications and source records attributed to S Zisook.

At least 109 records · Page 6Linked to original sources
PubMed1980

Evaluations of loxapine succinate in the ambulatory treatment of acute schizophrenic episodes.

138 acutely ill schizophrenic patients were treated with oral loxapine succinate for up to 4 weeks in nine studies, all of which shared an identical protocol. These nine, open-label studies were conducted primarily in outpatient settings. For most patients, loxapine, at daily dosages of 30-80 mg, was observed to provide safe, effective, and relatively immediate symptomatic relief and, in most cases, helped to keep acutely ill schizophrenic patients out of the hospital. Side effects, which occurred in 95 patients, were mostly mild and controllable and consisted mainly of extrapyramidal effects.

Acute Disease↗
PubMed1978

The hysterical personality--I. The healthy hysteric.

This paper examines the meaning and validity of 'hysterical personality disorders'. Theories and descriptions of hysterical personalities have been conflicting and often mutually incompatible, leading to a vague and imprecise nosology. No generally accepted specific inclusion criteria or follow-up studies are available; consequently, the diagnosis of 'hysterical personality disorder' has reflected adaptive as well as maladaptive traits. This paper critically examines the healthy dimension of Lazare's continuum of personality pathologies exhibiting hysterical traits. The continuum, in an attempt to reconcile the inconsistencies of this diagnosis, ranges from the relatively healthy (good, genital, true) hysteric, to the sick (bad, oral, 'so-called good') hysteric. But this paper concludes that here, too, evidence for diagnostic legitimacy is lacking. Women at the healthy end of the hysterical personality spectrum are best regarded as healthy and do not meet criteria for the diagnosis of a personality disorder.

Female↗
PubMed1978

Absence of hostility in outpatients after administration of halazepam--a new benzodiazepine.

A number of benzodiazepine have been shown to increase hostility and aggression. This study examines whether halazepam, a new benzodiazepine structurally very similar to diazepam, is associated with increases in hostility. Fifty-one adult outpatients in a double blind, 6 week study were randomly assigned either halazepam or placebo. Hostility was measured by changes in response on four different scales, the anger-hostility factor of the Patient Symptom Checklist and three MMPI hostility scales. The results of our study indicated that halazepam does not induce significant changes in hositility.

Adult↗
PubMed1977

Emotional factors in inflammatory bowel disease.

Inflammatory bowel diseases are not caused by emotional conflicts, but emotional factors influence both the pathogenesis and the course of the illness. Establishing a trusting physician-patient relationship is important in helping the patient to (1) avoid denial of illness or chronic illness behavior, (2) understand symptoms and diagnostic and treatment procedures, and (3) cope with loss of a key person or the threat of lessened self-control.

Adolescent↗
PubMed1977

Patients with psychogenic pain.

This article describes characteristics of groups of patients with a high probability of having pain complaints on an emotional basis. An approach to patients with psychogenic pain, including management suggestions, is emphasized, with particular reference to the use of extensive history for their identification and the importance of minimizing unnecessary medical and surgical procedures.

Abdomen↗
PubMed1976

Psychiatry: unresolved grief. Clinical considerations.

Unresolved grief refers either to the absence or to the prolongation of normal grief. It is identified by (1) painful response to recall of the deceased, (2) realization of not having accepted the loss or of not being able to grieve, and (3) unaccountable depression, emergence of medical symptoms on the anniversary of the loss, or both. Three clinical syndromes can be defined in relation to the stage at which the grief process has been arrested. Treatment involves encouraging patients to talk about the deceased and guiding them through a normal grief reaction. Psychiatric evaluation should be considered when suicidal ideation is present.

Adult↗