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Biomedical subjects

S York

Publications and source records attributed to S York.

11 recordsLinked to original sources
PubMed1993

Current perspectives: iron management during therapy with recombinant human erythropoietin.

Recombinant human erythropoietin (rHuEpo) has been associated with clinical and symptomatic improvements as well as improvements in quality of life in patients with anemia of chronic renal failure. However, resistance to rHuEpo therapy, related to insufficient iron stores, occurs often. Although many patients treated with rHuEpo take oral iron, patients continue to develop iron deficiency. Parenteral iron is a safe and effective alternative in replacing iron stores to sustain erythropoiesis in patients treated with rHuEpo.

Anemia, Hypochromic↗
PubMed1991

Self-administration of epoetin beta by peritoneal dialysis patients.

Recombinant human erythropoietin (epoetin) reverses the anemia of end stage renal disease. Benefits have been evaluated primarily in hemodialysis patients because of the ease of administration via existing intravenous access. Studies are under way to evaluate the feasibility of subcutaneous self-administration of epoetin in continuous ambulatory peritoneal dialysis (CAPD) patients. Preliminary study results, using the maintenance of target hemoglobin levels to measure success and a case study demonstrate the practicality of subcutaneous self-administration of epoetin in CAPD patients.

Adult↗
PubMed1990

Sudden monocular blindness associated with homozygous B-thalassemia in a young Liberian.

A 16-year old Liberian female presented with sudden monocular blindness. Physical examination and laboratory investigations were normal except that the patient had homozygous B-Thalassemia (HbA 58%, HbF 5% and HbA2 7.0%). Family study revealed that both parents had B-Thalassemia trait. We feel that the association of sudden monocular blindness with homozygous B-Thalassemia which has not been reported before, is not fortuitous but causal. It is therefore suggested that homozygous B-Thalassemia be added to the list of haemoglobinopathies (HbAS, SS and SC) that have been reported to cause blindness as complication.

Adolescent↗
PubMed1989

I spy efficiency.

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Ambulatory Care Facilities↗
PubMed1986

A corneal mold to restore normal corneal dimensions.

A corneal mold is described that provides an MK corneal button of normal thickness and curvature from an edematous, post-mortem button. The uniform, processed tissue can then be used for experimental refractive surgery.

Cornea↗
PubMed1984

Hypoglycemic coma induced by inadvertent administration of glyburide.

A 79-year-old nondiabetic woman was inadvertently given a 5-mg tablet of glyburide. Blood glucose concentration was 2.6 mmol/L three hours after ingestion. The patient was discharged 9 hours after ingestion and readmitted 10 1/2 hours after ingestion, in a hypoglycemic coma (blood glucose, 0.65 mmol/L). She was treated with two bolus doses of dextrose and intravenous dextrose. Her blood glucose was abnormal until hospital day 3. On hospital day 4, she was discharged with no apparent sequelae. This patient's severe reaction may have been due to mild renal insufficiency or concurrent use of timolol. Should inadvertent administration of glyburide occur in a patient with impaired renal function, the patient should be monitored for at least 24 hours.

Aged↗
PubMedDate not supplied

Ophthalmic triage.

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Emergency Medical Services↗