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Biomedical subjects

S Yabuki

Publications and source records attributed to S Yabuki.

At least 109 records · Page 6Linked to original sources
PubMed1980

Amyotrophic lateral sclerosis: a study of systemic complications in autopsy cases in Japan.

In a retrospective study involving 277 autopsy cases of amyotrophic lateral sclerosis (ALS) which had been published in the Annual of the Pathological Autopsy Cases in Japan, an investigation was made of concurrent visceral lesions. The results indicated that complications involving the digestive organs, urinary tract and supportive connective tissues were less frequent in ALS than in patients with degenerative diseases of the central nervous system who served as controls. Since a similar discrepancy was observed between patients with ALS and with encephalitis, it was postulated that the difference in incidences might not be simply explained by differences in patients' ages and the duration of illness.

Adolescent↗
PubMed1980

Fine structure in the thermal denaturation of DNA: high temperature-resolution spectrophotometric studies.

Fine structures which appear in the optical melting profile of DNA are examined from both the experimental and theoretical aspects. After a brief historical survey of the DNA melting experiments during the pre-fine-structure era in Section II, the high temperature-resolution experimental techniques which are essential to the investigation of fine structure are described in Section III. Then, the current status of the high-resolution study is reviewed first by a phenomenological description of the melting profile (Section IV) and then of the refolding profile (Section V), where a general idea about the cooperatively melting region and several factors affecting it is given. Sections VI and VII are devoted to the review of current theoretical works. Several well-established theoretical frameworks which correlate the base sequence with the melting phenomena are examined in terms of their rigorousness and usefulness. The molecular thermodynamic parameters concerning the DNA melting which have been evaluated by several research groups are compared and discussed. Finally, in Section VIII, current ideas on the correlation between the fine structure and genetic functions and genetic maps are reviewed. Some future problems relating to the fine structure are also discussed.

Animals↗
PubMed1979

Paroxysmal dysesthesia in multiple sclerosis.

Seven cases of multiple sclerosis with paroxysmal dysesthesias of an upper extremity were reported. This seizure characteristically is a purely sensory one induced by movements and is not accompanied by convulsions or a disorder of voluntary movements. In other ways it shares some features with other paroxysmal manifestations seen in MS. Clinical observations with subsequent neurophysiologic considerations have led to the hypothesis that paroxysmal dysesthesias are segmental symptoms with their foci lying in or about the spinal cord.

Adult↗