Search PubMed⌕ Search

Biomedical subjects

S Y Han

Publications and source records attributed to S Y Han.

At least 91 records · Page 5Linked to original sources
PubMed1991

Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program.

This study describes the results with immature human follicular oocytes harvested from unstimulated ovaries, matured in vitro, fertilized, and transferred to an agonadal recipient. Two hundred seventy immature oocytes were aspirated from 23 ovaries removed for various gynecological indications from August 1988 to October 1989. The numbers of follicular oocytes collected from ovaries were compared by patients' ages and the stages of menstrual cycle. Immature oocytes in vitro were incubated with either mature follicular fluid (FF) or fetal cord serum (FCS). The maturation rate in the mature FF group was 55.8%, significantly higher than the 35.9% in the FCS group. In addition, mature FF group was shown to provide a significantly higher fertilization rate than the FCS group (81.0% versus 31.6%). More fertilized eggs developed into normal embryos in the nonstimulated cycle group than in stimulated cycles with routine treatment. Finally, five embryos were transferred to a woman with premature ovarian failure on day 18 of a steroid replacement cycle. She subsequently delivered healthy triplet girls. These results suggest that in vitro maturation of immature oocytes from unstimulated ovaries with mature follicular fluid could be used successfully in a donor oocyte program after in vitro fertilization.

Adult↗
PubMed1990

Patient-initiated mobile mammography: analysis of the patients and the problems.

Patient initiation of mammographic screening is one method of increasing compliance with screening mammography guidelines. A low-cost screening project using a mobile van was developed at the University of Alabama at Birmingham. Analysis of the first 2,099 patients revealed that the participants were generally white (92%), more likely to have had a previous mammogram than the norm (33% in this study vs 19% in a 1986 Gallup survey), and relatively high-risk (30% having a breast cancer risk factor). The cancer detection rate was 6.2 per 1,000 women screened, with a biopsy rate of 1.3% and a positive predictive value of 48%. More than half the cancers detected were in situ lesions or invasive carcinomas smaller than 1 cm. Our results suggest that low-cost mobile mammographic screening can operate at appropriate levels of sensitivity and specificity and is well accepted by participants. Such projects require considerable preliminary planning, significant financial and time commitment by the physicians involved, and meticulous follow-up. A mammography management software system was developed to facilitate tracking of patients for routine and diagnostic follow-up studies and rapid communication of results. Although most follow-up studies and biopsies were done in the community, resistance in the medical community was significant and is perhaps the greatest impediment to such screening endeavors.

Adult↗
PubMed1990

Radiologic evaluation of continent urinary reservoirs.

A variety of methods are currently used for urinary diversion after cystectomy in adults. Radiologists are generally familiar with ileal and colonic conduits but are less familiar with the recently popularized continent urinary reservoirs. We describe and illustrate the surgical technique, normal anatomy, and normal radiographic appearance of a variety of urinary reservoirs, including the Kock pouch, Camey procedure, and various ileocecal reservoirs. Complications of various reservoirs are also discussed and illustrated.

Cecum↗
PubMed1988

Intestinal ischemia: comparison of plain radiographic and computed tomographic findings.

This article illustrates the radiographic and CT findings in 14 patients with proved intestinal ischemia or infarction. Gaseous bowel distention, thumbprinting and pneumatosis were the most frequent radiographic findings; intestinal distention, thickening of the bowel wall, engorgement of mesenteric vessels, and pneumatosis, the most frequent CT findings. The authors conclude that CT offers major advantages for evaluating patients suspected of having intestinal ischemia or infarction.

Adult↗
PubMed1987

Synthesis of side chain-modified iodothyronines.

New side chain-modified iodothyronines have been synthesized. They include: 1-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-1,2-ethanediol (T2EG); alpha-hydroxy-4-(4-hydroxyphenoxy)-3,5-diiodobenzeneacetic acid (T2HAA) and their 4-methyl ether derivatives (MT2EG, MT2HAA); 1-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-2-aminoethanol (T2EA); 1-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-1,2-ethaned iol (T3EG); 1-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-aminoetha nol (T3EA); and alpha-hydroxy-4-(3-iodo-4-hydroxyphenoxy)-3,5-diiodobenzeneacet ic acid (T3HAA). These model compounds are being used to study thyroid hormone metabolism and to determine structure-activity relationships of iododiphenylether derivatives.

Chromatography, High Pressure Liquid↗
PubMed1986

Pneumopericardium occurring as a complication of achalasia.

Esophagopericardial fistula is a rare complication of benign esophageal disease. It has not previously been described occurring in achalasia. The authors present such a case. This cause should be considered in the differential diagnosis of pneumopericardium in patients with achalasia. Early diagnosis is stressed and esophagoscopic examination should be performed if the result of barium swallow test is negative.

Barium Sulfate↗
PubMed1985

Hand-held real-time breast sonography.

The results of real-time hand-held sonographic breast examinations on 86 patients are presented. The technique is described in detail. Sonography was found to be a useful adjunct to the x-ray mammogram in three groups of patients: (1) patients with dense breasts and localized symptomatology or a suspicious area on x-ray mammogram; (2) patients with nonpalpable abnormalities discovered on x-ray mammogram; and (3) patients with palpable masses considered indeterminate on x-ray mammogram. The examination was also found useful for guiding needle aspiration biopsies, in patients with persistent nipple discharge, and in those with breast prostheses. Advantages of the hand-held real-time technique include supine positioning, the ability to flexibly orient the probe, improved resolution due to higher frequency transducers and the lack of compounding, and the ability to vary the amount of compression to assess tissue compliance and fixation. The disadvantage of decreased resolution in the near field can be overcome by attaching a detachable water-path step-off device to the transducer. Geometric distortion from the pressure of the transducer was not believed to be a problem. Hand-held sonographic technique is useful when attention can be directed to a specific area of the breast. The additional information provided results in fewer equivocal interpretations of the x-ray mammogram; however, it should not be used as a substitute for routine mammography.

Adult↗
PubMed1985

Perforation of the esophagus: correlation of site and cause with plain film findings.

The medical records and plain films of the chest and neck of 24 patients with esophageal perforation that had occurred either spontaneously or as a complication of instrumentation were reviewed. Plain films provide useful guidelines as to cause and location of perforation, and were found to be valuable in performing the subsequent confirmatory esophagram. Perforation of the distal esophagus usually results in pleural effusion or hydropneumothorax on the left, while perforation of the midesophagus tends to produce pleural effusion or hydropneumothorax on the right. Spontaneous perforation (Boerhaave syndrome) usually occurs in the distal esophagus, with resultant hydropneumothorax on the left. The plain films were unremarkable in about 12% of patients with esophageal perforation.

Adult↗
PubMed1985

Extraperitoneal gas: compartmental localization and identification of source.

We evaluated the plain films of the abdomen and chest in 24 patients with documented extraperitoneal gas collections. Compartmental localization of the extraperitoneal ectopic gas in these patients was as follows: the anterior pararenal space in 10 patients, the perirenal space in five and the posterior pararenal space in 15. In six of these 24 patients, the extraperitoneal gas was present in two compartments. The extraperitoneal gas collection resulted from perforation of the retroperitoneally located alimentary tract in 11, necrotizing pancreatitis in five, gas-producing infection in four and from extension of extra-alveolar air in three patients. Air insufflation of the scrotum was the cause of the extraperitoneal gas in another patient.

Emphysema↗
PubMed1984

Malignant tumors of the small bowel.

The four common types of small bowel malignancies have different clinical presentations, routes of metastatic spread, and prognoses, and may require selective treatment. A review of our experience over a 16-year period revealed 45 cases: 16 adenocarcinomas, 13 carcinoids, nine leiomyosarcomas, five lymphomas, and two fibrosarcomas. Adenocarcinomas tend to occur in the upper part of the small intestine, cause obstruction and occult blood loss, and metastasize to the regional nodes and liver. Carcinoids generally begin in the distal portion of the small bowel, may form rather large metastatic masses and cause obstruction from a metastatic mass or intussusception, and are often multiple. Leiomyosarcomas develop in any part of the bowel, may present a primary mass, gross hemorrhage, or perforation, and have blood-borne metastases. Lymphomas tend to occur in the distal part of the small bowel, with pain or mass formation, and spread via the lymphatics. Critical analysis of the clinical presentation and findings should allow preoperative recognition of the specific pathologic type.

Adenocarcinoma↗
PubMed1984

Perforation of the abdominal segment of the esophagus.

Five patients with perforation of the abdominal segment of the esophagus are described. In two patients with tear of the abdominal segment alone, perforation occurred into the retroperitoneal space. In the other three, there was a tear that extended above the diaphragm, and perforation was into both the thorax and lesser sac in one and into both the thorax and retroperitoneal space in the other two. The clinical manifestations and treatment of these patients differ from those of the more common intrathoracic perforation.

Abdomen↗