Biomedical subjects
S Wright
Publications and source records attributed to S Wright.
Experimental study of the current flow in the quantum Hall regime.
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Use of monosomics to map cloned DNA fragments in maize.
Monosomic maize (Zea mays L.) plants were generated using the r-X1 deficiency system, and the monosomy was confirmed both genetically and cytologically. Genomic DNAs prepared from a group of plants, each monosomic for one chromosome, were digested with restriction enzymes, electrophoresed in agarose gels, and blotted onto nylon membranes. Hybridization of labeled cloned DNA fragments to these blots proved efficient in assigning each fragment to the chromosome from which it originated. Cloned DNA has previously contributed to loci detection through the use of the restriction fragment length polymorphisms (RFLPs), these loci subsequently being arranged into linkage groups by segregation analysis. In this study, these linkage groups were assigned to specific chromosomes, facilitating the construction of a linkage map for maize containing 112 RFLP loci. An additional 35 loci were also assigned to chromosomes by this method; however, the linkage relationships of these loci to other RFLP loci on each chromosome remains undetermined.
Recombinant DNA technology and its social transformation, 1972-1982.
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Woolly hair naevi with systematized linear epidermal naevus.
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An institutional survey of tinea capitis in Harare, Zimbabwe and a trial of miconazole cream versus Whitfield's ointment in its treatment.
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Power, professions and practice.
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The joint appointment represents an important way forward for nurses to achieve their ideals.
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The effects of peer-teaching on student perceptions of class environment, adjustment, and academic performance.
This study explored the effects of a social studies peer-teaching intervention on student perceptions of class environment, adjustment, and academic performance. There were 45 students in the experimental group (E) and 46 controls (C) from four fifth-grade classes in a suburban, predominantly white, middle-class school. The Classroom Environment Scale (CES) and a School Opinion Survey were used to assess student views of the classroom. Students completed self-esteem and peer sociometric rating measures and teachers submitted adjustment ratings for all pupils. Report card and average monthly grades were recorded in social studies. After the intervention, Es compared to Cs came to see their classes as more Involved, Orderly and Organized, and Competitive, and reported being happier in class and enjoying aspects of their school work more. The groups did not differ in change in self-esteem. Both groups improved directionally in peer liking, though Cs did so more than Es. Teachers rated Es as having increased competence and decreased in problems after the program. Es did significantly better than Cs both on report cards and monthly social studies grades due primarily to the substantial improvement of Es with initially low academic status.
Essential fatty acids in the plasma phospholipids of patients with leprosy.
Plasma phospholipid essential fatty acids were investigated in 40 patients with leprosy and 40 controls. A significant reduction in linoleic acid was found in the leprosy patients, with an increase in its metabolite dihomo-gamma-linolenic acid. No difference was found between patients with multibacillary and paucibacillary leprosy. Patients treated for less than 6 months were found to have low levels of linoleic acid and high levels of dihomo-gamma-linolenic and arachidonic acid compared with patients treated for more than 6 months.
Comparison of a cream containing 0.1% dithranol in a 17% urea base (Psoradrate) with coal tar pomade in the treatment of scalp psoriasis.
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Atopic dermatitis and essential fatty acids: a biochemical basis for atopy?
The effects of dietary supplementation with evening primrose oil (Efamol) in 99 patients with atopic dermatitis were investigated in a double blind, controlled crossover study. Simultaneously, plasma phospholipid essential fatty acid status was determined in 50 of these patients before and after treatment. In a separate study, lymphocyte subsets and mitogen responses were investigated in 15 atopic patients before and after treatment. The conclusion is that evening primrose oil improves atopic dermatitis; an abnormality of the enzyme delta-6-desaturase is proposed to explain the biochemical findings. Finally, it is concluded that the therapeutic effect of evening primrose oil is unlikely to be mediated through a primarily immunological mechanism.
DNA sequences required for regulated expression of the human beta-globin gene.
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High-pressure tool injection injuries.
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