Occult papillary microcarcinoma of the thyroid: a potential pitfall of fine needle aspiration cytology? Is it possible to avoid it?
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Biomedical subjects
Publications and source records attributed to S Woyke.
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A case of 65 years of old female in which Reed-Sternberg cells were found in brush specimens from bronchial mucosa is reported. Histopathologic specimens from bronchial mucosa and lymph nodes were estimated too. We would like to direct attention to the necessity differential diagnosis Reed-Sternberg cells with adenocarcinoma cells in brush specimens from bronchial mucosa.
In this paper the authors described those of the breast fine needle aspirates which were difficult for interpretation e.g. clear-cut differentiation between benign and malignant character of the lesion could not be made. There were 40 such cases (1.96%) out of 2332 breast tumors biopsied between 1987-1989. In the cases that proved to be malignant on histology the authors described cytological features which speak in favour of malignancy. In the group of smears which proved to be benign on histology the authors described the features that imitate atypia and should not be misdiagnosed as malignant. The described criteria may be of some help in cytological diagnosis of breast masses.
The histological and cytological pictures of epithelial-myoepithelial carcinoma of parotid gland were described. It was pointed out, that in the Polish literature these tumours were previously called clear cell adenoma.
Clinical data and morphological features of the storiform neurofibroma, presenting as an exophytic tumor of the trunk in 30 years old white man are described. This benign tumor, is microscopically similar to dermatofibrosarcoma protuberans and differs from the letter by the presence of melanin containing cells.
Immunocytochemical methods (ER-ICA) by using monoclonal antibodies were applied to determine the presence of estrogen receptors (ER) in 44 primary breast cancers in women. Of this 48% of the tumours were classified as receptor positive. In these tumours the nuclei had a clearly positive heterogenous colouration. In three cases a positive reaction was also found in benign epithelial cells of the breast. ER determinations by ER-ICA method were compared with quantitative analysis carried out by using radioligand and immunoenzymatic methods. There was a strong correlation between immunocytochemical ER evaluations and quantitative methods. We also found a correlation of the menopause state and patients age and ER content.
The authors provide brief clinical data and cytologic description of two extracranial meningiomas presenting as a cervical mass. Regardless of the rarity of the meningiomas in the neck region, using morphological criteria described in this article it is possible to diagnose preoperatively such a tumor by aspiration cytology.
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Thin-needle aspiration biopsy (TNAB) was performed on 22 patients with orbital tumors. Nine patients were studied before the introduction of computed tomography (CT) and only two cytologic diagnoses could be established. Thirteen aspiration biopsies guided by CT were successful. The technique of the CT-guided TNAB of orbital tumors is described. The cytologic features combined with the clinical data made it possible to diagnose precisely 10 malignant orbital tumors that were either metastatic or primary. Two meningiomas and one abscess were also identified. There were no complications. The TNAB of orbital tumors under CT guidance appears to offer several significant benefits to the patients.
Nineteen years observation of two siblings with multiple juvenile hyaline fibromatosis is presented. This entity was described 14 years ago. It is concluded that this disease can be effectively controlled by surgical excision of all newly discovered subcutaneous tumors.
The authors summarize the current status of thin-needle aspiration biopsy of the prostate and evaluate the accomplishments and limitations of this method of diagnosis. Historical developments, indications, technique, contraindications, complications, cytology of aspirates, diagnostic efficacy of aspirates, and grading of prostatic carcinomas are discussed.
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