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Biomedical subjects

S Wolfe

Publications and source records attributed to S Wolfe.

115 records · Page 7Linked to original sources

Virulence factors of Escherichia cofi from cellulitis or colisepticemia lesions in chickens.

This study was designed to compare virulence factors of cellulitis-derived Escherichia coli to colisepticemic E. coli in order to clarify whether E. coli associated with cellulitis comprise a unique subset of pathogenic E. coli. Isolates were tested for serotype, capsule, aerobactin production, colicin production, the presence of the iss gene, and serum resistance. Untypable isolates made up the greatest percentage of each group. Serotypes O2 and O78 were the most commonly identified among both groups of isolates. No statistical differences in the distribution of aerobactin or colicin production, capsule, or iss gene were observed between groups. Cluster analysis showed that 90% of the E. coli isolates had greater than 42% livability in serum-resistance tests. No separation of colisepticemic vs. cellulitis E. coli isolates was observed on the basis of SR. Colicin production by E. coli was highly correlated with serum resistance (P = 0.0029). These data suggest that cellulitis E. coli have virulence traits similar to those of colisepticemic E. coli.

Animals↗

Public disclosure of process and outcome measures.

There is a long history of resistance to public disclosure of data comparing the quality of doctors or hospitals. Examples of data ultimately disclosed are risk-adjusted cardiac bypass surgery mortality data, cesarean section rates, doctor immunization practices, and state medical board rates of serious disciplinary actions. Recent studies on postoperative infection rates in Veterans' Affairs hospitals show large differences even after risk adjustment. It is inevitable that more comparative quality data involving both the process and outcome of medical care will be made public after proper adjustment for risks.

Benchmarking↗