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Biomedical subjects

S Wilson

Publications and source records attributed to S Wilson.

At least 631 records · Page 35Linked to original sources

Maternal perceptions of child behavior: handicapped versus nonhandicapped.

This study compares the ratings of child behavior in short stories by mothers of children with handicapping conditions versus those whose children had no handicapping conditions. Each of the mothers rated 12 short stories or vignettes and indicated their self-perceived level of stress. The results showed that the mothers of children with handicapping conditions expressed significantly greater stress levels and rated inappropriate child behavior in a more tolerant fashion than the mothers of children without handicapping conditions. This information may be of value to the dentist who treats patients with handicapping conditions, and it provides a greater understanding of the mothers' concerns and daily life stresses.

Adult↗

A comparison of opinions from parents of disabled and non-disabled children on behavior management techniques used in dentistry.

The purposes of this study were to compare the acceptance of pediatric dental behavioral management techniques by 40 parents of children with disabilities with that of 40 parents whose children were not disabled and to determine the effect of prior information on the level of acceptance for both groups of parents. An instrument containing a demographic questionnaire and using a visual analog scale asked parents to indicate acceptance level of hand-over mouth, sedation, restraint using Papoose board, and general anesthesia for either a check-up/cleaning, dental filling, or treatment of a toothache. One half of each parent group received a written description and rationale for the behavior management technique prior to rating acceptance, and the other half did not. Although differences were found between parents of the disabled and non-disabled and between those informed and not informed, only one technique and procedure (restraint for check-up/cleaning) was significantly different for acceptability (p < or = 0.05), and that was between uninformed parents of non-disabled children and informed parents of disabled children. We conclude that having a disabled child or receiving a prior rational for pediatric behavior management techniques was not significantly related to differences in acceptance of the techniques for the procedures described.

Adult↗

Time course of stomach mineralization, plasma, and urinary changes after a single intravenous administration of gadolinium(III) chloride in the male rat.

In a previous experiment it was reported that the intravenous administration of gadolinium chloride (GdCl3) to rats results in a discrete band of interstitial mineralization in the fundic glandular mucosa of the stomach. To investigate the time course for the development of this lesion and its relationship to plasma calcium and phosphate concentrations, 2 experiments were carried out in male Sprague-Dawley rats given a single intravenous dose of 0.07 mmol/kg GdCl3. Plasma calcium and phosphate concentrations approximately doubled between 30 min and 12 hr postdose but had regressed back to near normal values by 24 hr. However, there were no observable clinical signs in treated animals. Histologically, there was progressive mineralization of the lamina propria of the neck region of the fundic glands from 6 hr postdose, forming a distinctive mineral band by 12 hr postdose. At 7 and 14 days postdose the mineral deposits were accompanied by mucous cell hyperplasia, interstitial fibrosis, and a very sparse infiltration of inflammatory cells. By 56 days postdose only occasional mineral deposits remained. Transmission electron microscopy showed mineral first nucleated on collagen in the interstitium, but there was no evidence of cell necrosis. X-ray microanalysis showed that the interstitial mineral was composed of calcium and phosphate in the form of hydroxyapatite; gadolinium (Gd) was only very rarely identified. These findings are consistent with metastatic mineralization. The source, cause, and the exact nature of the excess plasma calcium and phosphate are unknown, and the possible significance of this effect for clinical use of Gd-containing chelates in nuclear magnetic resonance imaging requires further investigation.

Animals↗

Vitrectomy: a new challenge for the anesthesiologist.

A new surgical procedure, virtectomy, for alleviation of blindness caused by previously intractable vitreous disease, is described. Special demands of vitrectomy upon the anesthesiologist are enumerated. Problems presented by a patient population, 83 percent of whom suffered from severe diabetes mellitus and/or hypertension with a variety of complications, are discussed. Anesthetic technic used for 47 patients undergoing vitrectomy is described.

Adolescent↗

Local control and distant metastases in primary canine malignant melanomas treated with hyperthermia and/or radiotherapy.

Forty-three dogs with primary malignant melanoma were randomized to receive radiotherapy alone (XRT) or hyperthermia plus radiotherapy (delta + XRT). Tumour responses were analysed in terms of complete response rates, rate of one year disease free survival and the incidence and time to develop distant metastasis. The frequency of complete responses (CR) was greater with adjuvant heat (76 per cent vs 21 per cent for XRT; P = 0.001). A trend towards an improvement in one year disease free survival was observed with delta + XRT (23.8 per cent) as compared with XRT (7.7 per cent), but the difference was not statistically significant. The frequency of distant metastases was not different between the two treatments. Descriptors of intratumoural temperatures achieved during therapy indicated that higher CR rates could be achieved with higher minima. When minima were less than and greater than 20 Equivalent minutes at 43 degrees C (Eq43) the CR rates were 64 and 90 per cent, respectively. One year disease free survival rates and frequencies of distant metastases seemed to be correlated with the intratumoural temperatures as well. This was reflected in analyses examining temperature minima and maxima. Examination of patterns of failure suggested that the most plausible explanation for the correlation between intratumoural temperature and metastases was the high local failure rate (70 per in the heated group). The results of this study emphasize the need for further investigation of the influence of local hyperthermia as a part of curative therapy on the frequency of distant metastases.

Animals↗

Mass die-Off of Caspian seals caused by canine distemper virus.

Thousands of Caspian seals (Phoca caspica) died in the Caspian Sea from April to August 2000. Lesions characteristic of morbillivirus infection were found in tissue specimens from dead seals. Canine distemper virus infection was identified by serologic examination, reverse transcriptase- polymerase chain reaction, and sequencing of selected P gene fragments. These results implicate canine distemper virus infection as the primary cause of death.

Animals↗

Acknowledging preceptors: not an easy task.

Educators commonly discuss the need to reward nurse preceptors. A survey of 295 preceptors teaching nursing students found 118 nurses (36.6%) did not feel a reward was appropriate, while the remainder felt it was. When asked if they had enough support, 68 (22.9%) reported "no" and 213 (73%) reported "yes." Recommendations stemming from this research include: the need to redefine "reward" to be more congruent with the preceptor's perceptions; to provide acknowledgment to preceptors reflective of their educational and professional role; and to recognize that the ongoing communication and feedback with nursing faculty is a crucial factor in preceptors' perceptions of support.

Adult↗

The effect of electronic dental anesthesia on behavior during local anesthetic injection in the young, sedated dental patient.

PURPOSE: The purpose of this study was to evaluate the effectiveness of the 3M Electronic Dental Anesthesia (EDA) finger electrode on reducing sedated patient responsiveness during local anesthesia administration. METHODS: Thirty patients between the ages of 24 to 48 months, ASA I, and in need of treatment of maxillary anterior teeth using local anesthesia were used in this study. Each of the patients received chloral hydrate (CH) and hydroxyzine (50 mg/kg and 2 mg/kg, respectively). The patients were divided randomly in two groups. The experimental group received activated electronic dental anesthesia (AEDA) while the control group had a nonactive EDA (NAEDA). Physiological parameters were recorded and behavior was videotaped and rated using the Ohio State University Behavior Rating Scale. A repeated-measures ANOVA, Student's tests, and descriptive statistics were used. RESULTS: The results indicated that the heart rate and diastolic blood pressure of both groups were significantly affected as a function of time and dental procedures. A significant effect in the percent change of heart rate between groups was noted during local anesthetic injection with the NAEDA group having an increased heart rate. There was a higher occurrence of movement in the NAEDA compared to the AEDA. CONCLUSION: The EDA appears to be beneficial in reducing the discomfort, as judged by behavioral and physiologic observations, associated with local anesthetic administration in young sedated dental patients.

Analysis of Variance↗

Presenting characteristics and treatment outcomes for tongue lacerations in children.

PURPOSE: Tongue lacerations in children require treatment decisions by clinicians, but there is conflicting literature on the topic of suturing. METHODS: In this prospective study, 28 patients (mean age 3.0 +/- 2.3 yr) with traumatic tongue lacerations were triaged according to an existing protocol to determine if the laceration would be sutured. At least 2 weeks post-trauma, 22 patients were evaluated by examination or report for quality of result and post-trauma complications. The most common location was anterior dorsum. A fall at home was the most common situation. Mean delay from injury to treatment was 4.5 +/- 9.0 h. No statistically significant difference was found for quality of result or post-trauma morbidity between those lacerations sutured and those not. No significant relationship was found between quality of result and size of laceration or bleeding at the time of presentation. Time delay did not significantly affect the quality of result. CONCLUSION: Results suggest that suturing does not improve outcome or post-trauma course for tongue lacerations in young children.

Chi-Square Distribution↗

The effect of orally administered midazolam on children of three age groups during restorative dental care.

PURPOSE: The effects of orally administered midazolam on three groups of preschool children who differed by age only and required dental treatment were studied. Sixty-one children age 24-58 months participated in this institutionally-approved study. METHODS: Selection criteria for the children included: demonstrated disruptive behaviors; healthy (ASA I); required at least one restorative appointment involving a posterior quadrant; no known drug allergies; were between two and five years of age; and had no prior experience with sedative trials. The children were divided into three groups according to age: Group I (24-35 months), Group II (36-47 months), and Group III (47-59 months). Each child received midazolam 0.5 mg/kg orally 15 minutes before treatment. Behavior was evaluated using the Ohio State Behavior Rating Scale (OS). Physiological parameters including heart rate, oxygen saturation, systolic and diastolic blood pressure were also evaluated. Data were analyzed using chi-square, cross tabulation, descriptive statistics, ANOVA, t-tests, and regression and correlation analysis. RESULTS: Results indicated no statistically significant difference in behavior across all age groups as evaluated by the OS. CONCLUSION: No significant differences of clinical significance were noted.

Administration, Oral↗

Behavior management techniques among pediatric dentists practicing in the southeastern United States.

PURPOSE: This study identifies those techniques most often utilized by pediatric dentists practicing in the Southeastern United States. It also assesses how the utilization pattern may have changed within the last five years, and identifies those factors that may have influenced the changes as perceived by the practicing dentists. METHODS: A questionnaire was mailed to 528 pediatric dentists who were members of the American Academy of Pediatric Dentistry, or The Southeastern Society of Pediatric Dentistry, or both. RESULTS: The response rate after one mailing and one reminder was 64%. The majority of dentists utilized less aversive behavior management techniques (e.g., parents in the operatory and nitrous oxide oxygen) and had decreased or discontinued use of such controversial techniques as Hand-Over-Mouth-Exercise (HOME) and Hand-Over-Mouth-With-Airway Restriction (HOMAR). The majority of dentists reported that their reasons for changes in the utilization pattern for most techniques were parental influences and legal and ethical concerns. CONCLUSIONS: Chi square analysis indicated significant differences (P < 0.05) in the frequency of use of behavior management techniques and age of practitioner, American Board of Pediatric Dentistry status, type of specialty training, and type of practice.

Adult↗