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Biomedical subjects

S Weiner

Publications and source records attributed to S Weiner.

At least 217 records · Page 12Linked to original sources
PubMed1980

An analysis of the efferent connections of the septal area in the cat.

The neuroanatomical organization of the efferent connections of the septal area in the cat was analyzed by the use of anterograde ([3H]leucine radioautography) and retrograde (horseradish peroxidase histochemistry) tracing techniques. The results indicate that the lateral septal nucleus projects to the nuclei of the diagonal band, preoptic area, lateral hypothalamus, and supramammillary region. The projections of the septofimbrial nucleus supply the nuclei of the diagonal band and the medial habenular nucleus. Projection targets of the vertical limb of the diagonal band are widespread and include the preoptic area, lateral hypothalamus, anterior limbic cortex, amygdala, medial habenular nucleus, interpeduncular nucleus and hippocampal formation. The projection from the vertical limb to the hippocampal formation is organized in a topographical manner in such a fashion that cells positioned near the midline project to the dorsal hippocampus and adjoining subicular cortex while fibers originating from cells situated more laterally project to more ventral parts of the hippocampal formation. In general, the projections from the horizontal limb were similar to those from the vertical limb, but several differences were noted. Fibers arising from the horizontal limb are distributed to the ventral tegmental area and interpeduncular nucleus but this region seems to lack a projection to either the habenular complex or to the ventral aspect of the hippocampal formation. Fibers arising from the bed nucleus of the anterior commissure are distributed to the preoptic region, lateral hypothalamus, supramammillary region, posterior aspect of the medial mammillary nucleus and lateral habenular nucleus.

Animals↗
PubMed1980

Staining porcelain veneer restorations.

This article discusses basic principles and their application for the staining of porcelain veneer restorations. This procedure can be performed in the dentist's office and minimizes patient office visits.

Color↗
PubMed1980

Control of fowl cholera in Hungary.

Experiences of the control of fowl cholera in large poultry farms in Hungary are reported. A vaccination method combined with sulfaquinoxaline treatment was developed against fowl cholera. Studies were carried out for the determination of the therapeutic and toxic doses of sulfaquinoxaline in fowls experimetnally infected with Pasteurella multocida. Field experiences with Sukvin, a sulfaquinoxaline containing vaccine, against this disease are reported. Sukvin was produced by Phylaxia Serum State Institute, Budapest, Hungary, and has been generally used in that country since 1967.

Animals↗
PubMed1980

Antenatal diagnosis and treatment of a fetal goiter.

The sonographic diagnosis of a fetal goiter, confirmed at delivery, is described in a fetus exposed to large doses of propylthiouracil, which was administered to the mother. The pregnancy was also complicated by recalcitrant premature labor secondary to polyhydramnios. The intraamniotic instillation of thyroxine decreased the size of the fetal goiter, and numerous therapeutic amniocenteses permitted continuation of the pregnancy, so a mature infant with a goiter but no airway obstruction was delivered. Amniotic fluid reverse-T3 assays confirmed fetal utilization of the thyroxine. Fetal thyroid physiology is discussed briefly along with the benefits of the antenatal sonographic diagnosis of fetal goiter.

Adult↗
PubMed1980

Amniotic fluid phospholipids measured by continuous-development thin-layer chromatography.

We describe a one-dimensional thin-layer chromatographic system for separation of amniotic fluid phosphatidylcholine, sphingomyelin, phosphatidylglycerol, phosphatidylinositol, phosphatidylserine, and phosphatidylethanolamine in amniotic fluid. We utilize short-bed continuous development and "high performance" thin-layer chromatography. Phospholipids are detected with an antimony molybdate staining reagent and quantitated by transmittance densitometry. This system is more sensitive to changes in lecithin/sphingomyelin ratios than are planimetric evaluations.

Amniotic Fluid↗
PubMed1979

Aspartic acid-rich proteins: major components of the soluble organic matrix of mollusk shells.

DEAE-cellulose ion-exchange chromatography separates soluble organic matrix components of three mollusk shells, each from a different taxonomic class, into analogous subfractions. The proteins of all subfractions are enriched in acidic and polar amino acids. In each chromatogram, however, the subfraction which contains the major portion of total protein also contains the highest concentration of aspartic acid. Thus the major components of the soluble organic matrix are aspartic acid-rich proteins. The identification of these proteins in mollusks, together with the known occurrence of aspartic acid and phosphoserine-rich proteins in vertebrate tooth dentin, emphasizes the fundamental importance of such acidic proteins in the processes of mineralization.

Amino Acids↗
PubMed1979

Metabolism of cholecalciferol in land snails.

1. Radioactively labelled cholecalciferol was injected into the land snails Levantina hiersolyma and Theba pisana. Three metabolites (C, D and E), more polar than cholecalciferol, were found. 2. Metabolite C was found to be identical with 25-hydroxycholecalciferol. On injection of 25-hydroxy[26,27-3H]cholecalciferol, metabolite E was predominantly formed. Metabolite D was predominantly formed from cholecalciferol. Metabolites D and E differ from any known cholecalciferol metabolites. 3. The intestine was found to be the tissue capable of carrying out the transformation of 25-hydroxycholecalciferol into metabolite E. 4. 25-Hydroxycholecalciferol and metabolite E were localized in the digestive gland of the snail, the tissue responsible for the absorption of Ca2+ and its storage. Metabolite D was not localized in any specific tissue.

Animals↗
PubMed1979

Unsuspected aortic dissection: the chronic "healed" dissection.

Of all aortic dissections, 10% are chronic. Typically they arise distal to the left subclavian artery and have reentry points into the true lumen. Pain may be minimal or absent and patients often present with cardiac failure. Chronic dissections are more likely to appear radiographically as atherosclerotic aneurysms on a chest film than are acute dissections. Four cases of chronic dissections found incidentally during angiography are presented.

Acute Disease↗
PubMed1977

The influence of ovarian denervation and nerve stimulation on ovarian contractions.

Two techniques were used to study the neuromuscular control of rabbit ovarian contractions. First, the ovary was denervated by stripping its artery. Spontaneous contractions were noted, as was a normal response to exogenously administered adrenergic agents. Second, the ovarian nerves were electrically stimulated in an in vitro perfused ovary system. Inhibition of ovarian contractions was noted, and the additive effects with adrenergic agents suggested a betamimetic effect of nerve stimulation in the estrous rabbit. After administration of exogenous human chorionic gonadotropin, the response was reversed. The significance of the contribution of a neuromuscular mechanism to the control of ovulation is discussed.

Animals↗
PubMed1976

Characterization of 80-million-year-old mollusk shell proteins.

Fossil glycoproteins of the soluble organic matrix are present in an 80-million-year-old mollusk shell from the Late Cretaceous Period. Discrete molecular weight components, as determined by gel electrophoresis, are preserved. The fossil organic matrix was compared with the organic matrix of a living representative species of the same superfamily. A particular repeating amino acid sequence, found in contemporary mollusk shell proteins, was identified in the fossil glycoproteins. The ultrastructure, mineralogy, and chemistry of the inorganic components of the fossil and contemporary shells provide information on the state of preservation of the fossil. The use of fossil shell proteins to further our understanding of molecular evolution is discussed.

Amino Acids↗