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Biomedical subjects

S Watt

Publications and source records attributed to S Watt.

At least 37 records · Page 2Linked to original sources
PubMed1998

Surviving social assistance: 12-month prevalence of depression in sole-support parents receiving social assistance.

BACKGROUND: Although it is generally recognized that poverty and depression can coexist among single parents receiving social assistance, there is insufficient research on this topic. The goals of this study therefore were to investigate the prevalence, correlates and health care expenditures associated with depression among sole-support parents receiving social assistance. METHODS: Sole-support parents who had applied for social assistance in 2 regions of southwestern Ontario were included in the study. Depression was diagnosed with the 1994 University of Michigan Composite International Diagnostic Interview short forms. RESULTS: The 12-month prevalence rate of depressive disorder among the parents interviewed was 45.4% (345/760). A total of 247 (32.5%) had major depressive disorder alone, 19 (2.5%) had dysthymia, and 79 (10.4%) had both major depressive disorder and dysthymia ("double depression"). Those with major depressive disorder, particularly double depression, had significantly higher rates of coexisting psychiatric disorder than those without depressive disorders. Parents with depression reported higher rates of developmental delay and behaviour problems in their children than parents without depression. Expenditures for health care services were higher for parents with depression and for their children than for parents without depressive disorder and their children. INTERPRETATION: Single parents receiving social assistance have high rates of depression. Such parents with depression also have higher rates of other psychiatric disorders and higher expenditures for health care services, and their children have higher rates of developmental delay and behaviour problems.

Adaptation, Psychological↗
PubMed1997

Surface dyslexia in nonfluent progressive aphasia.

This article presents the case of a 59-year-old male, JH, with a 6-year history of primary progressive aphasia (PPA), a disorder characterized by isolated language deterioration with relative preservation of other cognitive abilities. JH also shows typical features of surface dyslexia, a reading disorder exemplified by the selective preservation of phonological reading. One recent theory is that surface dyslexia in individuals with PPA results from a loss of semantic knowledge. In this paper we consider an additional possibility and present data supporting the notion that surface dyslexia may also arise from the malfunction in the links between semantic representations and phonology. JH has remarkably preserved lexical semantic knowledge when assessed on tasks that do not require verbal output. Further, item-by-item comparisons of his oral reading and comprehension ability show no significant correspondence between his reading and semantic knowledge. These findings lead us to conclude that, in JH's case, the surface dyslexia is attributable not to a semantic deficit per se but rather to the inability to access phonological information from semantics. JH's language profile is considered in relation to potential sources of surface dyslexia and other cases of progressive aphasia.

Aphasia, Broca↗
PubMed1997

Impaired visual search in patients with unilateral neglect: an oculographic analysis.

The attentional deficit underlying hemispatial neglect was examined through a detailed analysis of the eye movement performance of a group of neglect patients. Relative to normal subjects and to patients with hemianopia without neglect, patients with left neglect make fewer fixations and have shorter inspection time on the contralesional left side. They also start their search to the right of the midline and make significantly more fixations and longer fixations on the ipsilesional right side. A positive linear relationship between horizontal location and frequency of fixations was noted for the neglect group as a whole, as well as for most of the individual patients. These findings strongly endorse the view that the attentional deficit in neglect follows a left right gradient. The peak of the maximum fixations, however, is not on the extreme right, as might be predicted by a strict gradient account, and is more consistent with recent views that the midsagittal plane of the viewer is redirected rightwards. These findings provide a detailed analysis of the eye movement patterns in neglect patients and demonstrate the robustness of oculographic analysis for examining their altered spatial representation.

Aged↗
PubMed1997

Age, adjustment, and costs: a study of chronic illnesses.

Much concern has been expressed about increasing health costs associated with an aging population. In relation to chronic conditions, this study demonstrates that cost seems to be a function of adjustment to the chronic condition rather than of age in and of itself. We know from previous work that people with poor psychosocial adjustment cost considerably more than do people who are either moderately or well adjusted and this study shows that older, poorly adjusted persons are no more costly than their younger counterparts.

Activities of Daily Living↗
PubMed1996

Measuring rebreathing in spontaneous ventilation. A new lung model.

The performance of breathing systems is tested by means of physical lung models. We describe a new lung model, allowing direct measurement of the dead space/tidal volume ratios produced by any breathing system at different fresh gas flows. The model allows a range of different patterns of spontaneous respiration to be studied. Although rebreathing is measured by capnography, the design ensures that the results are unaffected by changes in carbon dioxide inflow, or even calibration drift in the capnograph.

Anesthesia, Closed-Circuit↗
PubMed1995

More effective and less expensive: lessons from five studies examining community approaches to care.

Does the nature of community health services used by chronically ill clients and their caregivers have an impact on utilization of services, expenditure and well-being outcomes? A series of five studies, (four historic cohort and one randomized trial) examined clients suffering from a variety of chronic conditions in a number of community settings in different regions of Southern Ontario. Study sample composition and size varied. Each study was designed to quantify the well-being outcomes, and expenditure associated with different community approaches is covered under a nation-wide system of health insurance plans. As a collective, these studies represent increasing methodological rigor. Multiple-perspective client well-being outcome measures were used. Caregiver burden was also analyzed. A common approach to quantification and evaluation of expenditure for service consumption was applied across all five studies. The nature of community health services (proactive versus reactive approaches to care) was found to have direct and measurable impact on total expenditure for health service utilization and client well-being outcomes. A recurring pattern of lower expenditure for community health service utilization and equal or better client outcomes was associated with well-integrated proactive services when compared with individual fragmented, reactive approaches to care. The main lesson emerging from examining the five studies on approaches to community care is that it is as, or more, effective and less expensive to offer complete proactive health care services to chronically ill people in the early stages of their illness than to provide services on demand in a piecemeal manner.

Caregivers↗
PubMed1995

A study of absence rates in male and female employees working in occupations of equal status.

The objective of this study was to investigate the extent to which occupational status and age influence absence rates in male and female employees. This involved collection of data for absences of one or more calendar days, including the length of absence and the location, age, occupational status and gender of the worker. This information was supplied by personnel departments on standardized forms. The study took place in three occupational groups in two organizations with equal work status for men and women, located in England, Scotland and Northern Ireland. In total, we studied 2561 workers (77.8% male, 22.2% female) in employment during the three months between April and July 1992. More women than men took time off work in the study period. Female absence exceeded male absence for spells of absence in ratios between 1.3:1 and 1.5:1, and for days in ratios between 1.2:1 and 1.9:1; age standardization removed the differences in spell rates (in all but one group) and total absence (days). Both men and women took fewer but longer spells of absence with increasing age. Men were more likely to take spells lasting more than one day, but women took more multiple single-day spells. Relative job status affected absence rates, with professional staff taking less absence than support staff. In this workforce controlled for occupation, significant differences in crude absence rates were observed between males and females. Age standardization explained the difference in spell rates in most groups. This suggests that there is little true difference in absence rates and highlights the importance of age standardization in such studies.

Absenteeism↗
PubMed1995

Career management support for nurses.

The downsizing of many areas of the NHS is now affecting nurse education as it moves into the Further/Higher Education sector. Many staff are terminating their employment relationship through early retirement. Describes a career management workshop run for such staff and makes reflections on careers, especially of the objective and subjective kind.

Career Mobility↗
PubMed1995

Behavioral auditory thresholds for sinusoidal electrical stimuli in the cat.

Behavioral thresholds were measured in four cats by training them to respond behaviorally to acoustic auditory stimuli using food as a reward in an operant reinforcement paradigm. Following training, the subjects were implanted unilaterally with either a scaled-UCSF electrode containing four contacts or an electrode array containing eight intracochlear contacts and one extracochlear contact under temporalis muscle. Behavioral thresholds for electrical stimuli were obtained as a function of sinusoidal frequency, duration, and electrode configuration. Threshold functions for both electrode types and all animals had minima between 48 and 125 Hz and, in general, were relatively flat below this minima; functions increased at 3-6 dB/octave from 96 Hz to 1 kHz. Threshold varied predictably as a function of electrode configuration, with thresholds decreasing as much as 20 dB as electrode spacing was widened from a radial bipolar (200-microns separation) to a monopolar configuration (apical stimulating and temporalis return). With long-duration stimuli, increasing the electrode separation systematically increased the slope of the threshold-versus-frequency contours in all animals. Irrespective of electrode type or configuration, charge/phase thresholds for single-cycle sinusoids were relatively flat for stimulus periods up to 1-5 ms, approximating a constant charge/phase determination of threshold. At phase durations greater than 5 ms, charge thresholds increased at a rate slightly above 6 dB/octave (constant peak current), which was suggestive of neural accommodation. Thresholds for the cat share many features with those reported for implanted humans and monkeys.

Acoustic Stimulation↗
PubMed1993

Single space combined spinal-extradural technique for analgesia in labour.

We have used the single space combined spinal-extradural technique for mothers requesting analgesia in labour. Intrathecal plain bupivacaine 5 mg produced a median time to analgesia of 3 min. There was inadequate abdominal analgesia after 10 min in 16% of recipients, although all had good perineal analgesia. The median height of block was T8 (range T4-L2) and mean duration of analgesia 72 (SD 21) min. Hypotension occurred in two of 30 mothers, but responded to fluids and ephedrine. There were no post-spinal headaches. This technique is suitable for those parturients requesting analgesia in active labour who may not have time to achieve extradural analgesia before delivery. The extradural catheter is used to improve analgesia if the subarachnoid block is inadequate, or if labour continues beyond the duration of the subarachnoid block.

Adult↗
PubMed1989

Complex lymphoid and epithelial thymic tumours in Thy1-myc transgenic mice.

T-lymphocyte development takes place mainly in the thymus, where stromal cells of epithelial and haemopoietic origin are involved in inductive and selective mechanisms, which enable specific lymphocyte populations to migrate to the periphery and establish a network of immune responses. Experiments with intact animals have clarified the precursor-product relationships between thymocyte subpopulations, but the molecular mechanisms of cell interactions in the thymus are difficult to study in vivo. In an attempt to expand thymic cell populations in vivo and maintain them in vitro for such studies, we directed high levels of expression of the murine c-myc proto-oncogene in transgenic mice by inserting it into the mouse Thy-1 transcriptional unit. Such mice develop thymic tumours which contain proliferating thymocytes and, interestingly, expanded populations of epithelial cells. Both cell types can be maintained in vitro.

Animals↗