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Biomedical subjects

S Wanvarie

Publications and source records attributed to S Wanvarie.

13 recordsLinked to original sources

Quality of life and functional status of patients with hip fractures in Thailand.

Measurement of quality of life and functional status provides important additional information for priority setting in health policy formulation and resource allocation. Hip fracture has been a concern in health planning in developing countries due to an increasing trend, as reported in several studies. Ironically, in developing countries, studies of the impacts of hip fracture on quality of life and functional status are rare. This prompted our team to seek evidence of the impacts using a longitudinal follow-up approach in a Thai setting. In this study, health-related quality of life (HRQOL) before and after hip fractures was evaluated in 250 Thai patients. Measurement of HRQOL was based on a modified SF-12 questionnaire, which was developed with a realization of the following demands: 1) cultural sensitivity of measurement tools; 2) disease-specific HRQOL measurement and 3) feasibility of conducting field work. Functional status was measured using an adapted version of the Index of Activity of Daily Living (ADL), which was previously developed in another setting in Thailand. Mild, moderate and severe deficits in quality of life were found in 36%, 60%, and 4% respectively, of surviving patients. The number of patients with physical functioning dependency, as measured by the ADL, also increased significantly in all 10 activities assessed. Comorbidities were associated with deficits in health-related quality of life but age, sex, income, education level, and surgery were not. Our findings indicate that hip fracture could lead to crippling consequences, with a pronounced effect on the quality of life of Thai patients. Further studies using control groups and longitudinal design are needed to validate the results of this study.

Activities of Daily Living↗

Physical activity and risk factors for hip fractures in Thai women.

Hip fractures are among the most important causes of ill health and death among elderly people. Several potentially modifiable risk factors have been reported. Most claimed physical activity as a promising, inexpensive preventive measure for hip fracture. However, knowledge about risk factors for hip fracture in Asian populations is very limited. We therefore conducted a case-control study to assess the relationships between physical activity and risk of hip fractures in Thai women. From 14 hospitals in Thailand, 229 cases with a radiologically confirmed first hip fracture were enrolled. Two hundred and twenty-four controls were randomly recruited from the same neighborhood and were matched to the cases by age within a 5 year range. Information on physical activity as well as other potential confounders was obtained through personal interviews. Multivariate logistic regression revealed that past physical activity was protective in both very active and active women (OR = 0.67, 95% CI = 0.40-1.12 for moderately active women and OR = 0.20, 95% CI = 0.10-0.38 for very active women; p value for trend < 0.01). Recent physical activity reduced the risk to about two-thirds (OR = 0.33, 95% CI = 0.19-0.60 and OR = 0.35, 95% CI = 0.18-0.69 for moderately and very active women respectively). In addition, breastfeeding was identified to be a protective factor (OR = 0.87, 95% CI = 0.80-0.94). In contrast, the following risk factors were identified: current use of antihistamine (OR = 13.96, 95% CI = 1.38-141.13) or traditional medicine (OR = 7.66, 95% CI = 2.71-21.63), underlying cerebrovascular diseases (OR = 6.53, 95% CI = 2.10-20.34), history of fracture (OR = 4.04, 95% CI = 1.26-12.99), parental Chinese racial background (OR = 2.52, 95% CI = 1.49-4.23), alcohol consumption (OR = 2.30, 95% CI = 1.04-5.09).

Activities of Daily Living↗

Physical activity and risk factors for hip fractures in Thai men.

To test the hypothesis that hip fracture is associated with physical activity in Thai elderly men, a case-control study was conducted in Bangkok, Thailand. A total of 187 men aged 51 years over, resident in Bangkok, admitted consecutively with a radiologically confirmed first hip fracture were studied. 177 age-matched community controls were randomly recruited from the same neighborhood of the cases. Physical activity was independently associated with reduced risk of hip fracture after controlling for confounding factors. Very active and active past physical activity markedly reduced risk of hip fracture in comparison to subjects with inactive past physical activity. Recent active physical activity was also protective against hip fracture. This prompts a need to identify strategy to promote physical activity among the elderly and at an early age.

Adolescent↗

Coverage of public reimbursement scheme for traffic accident victims in Thailand.

Traffic injury is a major threat to public health. Loss of lives and property due to traffic accidents raise concern not only among the public but also the government. As a result, the Motor Vehicle Accident Victim Protection Act was enacted in order to provide compensation for traffic accident victims and their relatives in 1992. Three years after the Accident Victim Protection Act came into effect, this study, through telephone survey, revealed that less than 10 per cent of traffic accident victims were reimbursed for medical care cost by the law. The process of reimbursement was found to be cumbersome. In addition, only 18 per cent of motor vehicles were found holding insurance policies as required by the law.

Accidents, Traffic↗

Melioidosis: certain interesting presentations and treatment.

Eight cases of melioidosis with different clinical presentations are described. The compromised host defense is evident in view of the underlying conditions in all cases. Treatment with appropriate antibiotic combinations proved to be effective in curing the disease.

Adolescent↗