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Biomedical subjects

S Wang

Publications and source records attributed to S Wang.

At least 523 records · Page 29Linked to original sources
PubMed2000

[Insulin secretion and resistance during pregnancy in women with glucose intolerance].

OBJECTIVE: To investigate whether insulin secretion and resistance are different in glucose tolerant and intolerant women with normal pre-pregnant body mass index (BMI) during late pregnancy and to find out if there is association between gestational diabetes and insulin resistance syndrome. METHODS: On the basis of a 4-hour oral glucose tolerance test (OGTT), 32 gestational diabetes mellitus (GDM) patients, 21 gestational impaired glucose tolerant (GIGT) patients, and 50 normal glucose tolerant (NGT) cases were selected from uncomplicated pregnant women. Those had normal pre-pregnant BMI who had a 1-hour 50-g glucose-screening test (> or = 7.2 mmol/L), performed between 24-28 weeks of gestation. During the OGTT, several indexes of insulin resistance, insulin secretion, lipid metabolism were measured in addition to the standard glucose measurements. RESULTS: Glucose area under curve (GAUC), insulin area under curve (IAUC), insulin sensitivity index (ISI) transformed to natural logarithm and triglycerides (TG) are all significantly higher (P < 0.05) in GDM women. The means of these indexes in GDM group are 26.3 mmol/L.h-1, 276.5 mU/L.h-1, 4.2 and 3.2 mmol/L, respeetively. On the other hand, however, the differences of these indexes (except TG) between GIGT and NGT women are not statistically significant. The ratio of IAUC/GAUC has an increasing trend from GDM group, GIGT group to NGT group (10.5, 11.4 and 11.7, respectively), but the difference is not statistically significant. Multiple correlation coefficient study demonstrated that ISI is significantly positively correlated with GAUC, IAUC and TG (P < 0.01). CONCLUSIONS: Compared with NGT women, GDM women has impaired insulin secretion, abnormally increased insulin resistance, and relatively dyslipidemia. GDM seems to be a component of the syndrome of insulin resistance that provides an excellent model for study and prevention in a relatively young aged group.

Diabetes, Gestational↗
PubMed2000

[Studies on relationship between exposure to low concentration of mixed benzene and lower quality of semen and very early fetal loss].

OBJECTIVE: To study the effects of exposure to low concentration of mixed benzene on their semen quality and very early fetal loss (VEFL) in the occupational population. METHODS: Environmental monitoring and biological monitoring were conducted in 126 employees exposed to mixed benzene and 60 unexposed ones selected from a large petrochemical corporation and a large chemical fiber corporation. Quality of semen in 70 male workers in the exposed group and 90 male internal controls and 132 male external controls were analyzed, and urinary beta-human chorionic gonadotropin (beta-hCG) was determined for 42 female exposed workers and 49 female internal controls and 118 external controls. RESULTS: 1. Exposure to mixed benzene mainly existed in low concentrations (0.7-27.0 mg/m3) in the petrochemical corporation, and urine concentration of t, t-MA in the workers correlated significantly to benzene concentration in ambient air of the workshops (r = 0.64, P = 0.03). 2. The sperm progression and motility in the exposed (1.97 +/- 0.63 and 0.55 +/- 0.16) and the internal control (1.97 +/- 0.69 and 0.55 +/- 0.17) groups were significantly (P < 0.05) lower than those in the external control group (2.56 +/- 0.61 and 0.60 +/- 0.13), however, the sperm abnormality rates in the exposed and internal control groups were significantly (P < 0.01) higher than those in the external control group, and the summary abnormality rate of sperm in the exposed group (85.71%) was higher than that in the internal (70.00%) and external control (76.51%) groups (P < 0.05). 3. The incidence rates of the VEFL in female workers and the cyclic occurrence of VEFL both in the exposed and internal control groups (10.42% and 9.60%) were higher than those in the external control group (5.09%), with statistical significance (P < 0.05). CONCLUSIONS: Exposure to low concentration of mixed benzene maybe correlated with the declined quality of semen and VEFL in occupational workers, and urinary t, t-MA and beta-hCG can be used as biomarkers of exposure and effect, respectively.

Abortion, Spontaneous↗
PubMed2000

[The efficacy of antiviral antibiotic 17997 on treatment of HSV-1 infected guinea pig skin infection].

OBJECTIVE: To study the treatment efficacy of antiviral antibiotic 17997 against HSVl infected guinea pig skin infection. METHODS: Guinea pig skin was infected by HSV1. 24hrs or 48hrs of post infection local treatment of 0.3% 17997 cream was started, tid for five days. In the mean time, acyclovir treatment, cream treatment and virus control were included. RESULTS: Local treatment of 0.3% 17997 cream showed therapeutic effects, it reduced the average scores of skin lesion, accelerated crusting-time and healing-time. CONCLUSIONS: 0.3% 17997 cream showed significant treatment efficacy when compared with cream and virus controls by reducing skin lesion scores and healing-time. The treatment efficacy of 3.0% acyclovir cream was a little bit better than 0.3% 17997 cream.

Acyclovir↗
PubMed2000

[The expression of P21 and P15 proteins in liver tissue of chronic viral hepatitis and hepatocellular carcinoma and their relation to cell apoptosis].

OBJECTIVE: To study the expression of P21 and P15 proteins in liver tissue of chronic viral hepatitis (CH) and hepatocellular carcinoma (HCC) and their relation to cell apoptosis. METHODS: The expression of P21 and P15 proteins in 36 CH patients liver tissues were detected by immunohistochemistry and the DNA damage of the hepatocytes were detected by TDT mediated dUDT nick and labeling (TUNEL). 10 cases of HCC were also studied. RESULTS: P21 and P15 proteins mainly distributed in the interstitium of portal areas, the piece meal necrotic sites and the nuclei and cytoplasm of the hepatocytes. The higher expression of P21 and P15 proteins in the interstitium and nuclei of the hepatocytes was seen in CH as compared with that in HCC. The levels of expression of P21 and P15 in moderate and severe type CH were higher with that of the mild type CH (P <0.05). The correlative coefficient of expression of P21 and P15 with the DNA damage of hepatocytes were 0.56, 0.51 respectively (P <0.01). CONCLUSIONS: The enhanced expression of P21 and P15 proteins in CH correlated with the injury of liver tissues and apoptosis of hepatocytes.

Adult↗
PubMed2000

[Determination of scalp ER and AR of patients with male pattern baldness and the effects of hair transplantation on them].

OBJECTIVE: To study the role of sex hormone receptor capacity of the scalp in male pattern baldness(MPB). METHODS: Estrogen receptor(ER) and androgen receptor(AR) assays were performed using fluorescent steroid hormone conjugate technique (FSHCT) in hairness and bald scalp in 8 patients with MPB. Changes of ER and AR capacity in recipient and donor sites of hair transplantation in MPB scalps were examined. RESULTS: The percentage of AR staining cells in the outer root sheath, sebaceous gland and bulb papilla of the lesional scalps was significantly higher than that of hairness scalps (P < 0.01). The percentage of ER positive cells in the outer root sheath of lesional scalps increased significantly (P < 0.01). CONCLUSION: Changes of contents of sex hormone receptors(SHR) in some sensitive area of the scalp induce MPB.

Adult↗
PubMed2000

[Urethra fistula repair without using a urethral stent].

OBJECTIVE: To report the experience in fistula repair without a urethral stent. METHOD: During the operation, the wound after approximating the epithelium was made twice the diameter of the fistula. Then an adjacent flap was turned over to cover and close the fistula. 50 fistulae in 37 patients were repaired without using a urethral stent after the operation. RESULT: There has been no recurrence in the past 7 years. CONCLUSION: This method is one of the best ways for fistula repair and has a bright prospect in application.

Humans↗
PubMed2000

[The superficial vein, cutaneous nerve and its nutrient vessels in the forearm: anatomic study and the clinical implication].

OBJECTIVE: To provide an anatomic basis for designing the flap pedicled with neurocutaneous nutrient vessels, and for further understanding of this flap and its relations with other local venous flaps. METHODS: Microanatomy and red-and-blue latex injection transparency method were applied to study 1. The medial antebrachial cutaneous nerve (MACN), the lateral antebrachial cutaneous nerve (LACN) and their nutrient vessels; 2. The relationship between the basilic vein and MACN and its nutrient vessels; and 3. The relationship between the cephalic vein and LACN and its nutrient vessels. RESULTS: MACN is vascularized by paraneural vessels and LACN is by both paraneural vessels and the long artery. MACN is accompanied by its paraneural vessels and the basilic vein, so do LACN by its nutrient vessels and the cephalic vein. The distance range from the cutaneous nerve to its accompanying superficial vein is less than 1 cm, to its paraneural vessels is less than 0.4 cm; and the distance range from the paraneural vessel to the superficial vein is about 0.3-1.2 cm. CONCLUSIONS: A flap pedicled with cutaneous nutrient vessels could be designed along a superficial vein. The type of flap might be different because of the different neurocutaneous blood supply. Some locally transferred venous flap might be a flap pedicled with neurocutaneous nutrient vessels.

Adult↗
PubMed2000

[Repair of soft tissue defect of the hand with a fascia lata flap by microvascular anastomosis].

OBJECTIVE: This is to report the clinical experience in repair of the soft tissue defects of the hand using a free fascia lata flap and skin graft. METHODS: Eight cases of soft tissue defects of the hand were repaired with a fascia lata flap by means of microvascular anastomosis. The size of the fascia lata flap ranged from 2.5 cm x 7 cm to 6 cm x 16 cm. RESULTS: All the fascia lata flaps survived completely with satisfactory results. CONCLUSION: The flap is nourished by the descending branch of the lateral femoral circumflex artery and seems to have a constant vascular supply and a long pedicle. The dissection of the flap is easy. The flap is thin and very suitable for repair of soft tissue defects of the hand.

Adolescent↗
PubMed2000

[Mixing of Cunninghamia lanceolata with Michelia macclurei and restoration of self-sustaining mechanism in G. lanceolata plantation].

The formation of self-sustaining mechanism is one of the major objectives for the sustainable management of plantations. In this study, the incorporation of different proportions of native Michelia macclurei into Cunninghamia lanceolata plantation was practiced to restore the degraded C. lanceolata plantation, and the comparison of nutrient cycling characteristics and soil nutrient concentrations was made among four types of plantation stand with different mixed rate of native M. macclurei representing four different restoration stages of degraded C. lanceolata plantations. With the increase of the proportion of M. macclurei in the plantation, the litterfall and returned nutrients N, P, K, Ca and Mg increased. The nutrient cycling efficiency increased significantly, e.g., that of N and Mg increased from about 0.1 for the degraded pure C. lanceolata plantation to above 0.5 for the pure M. macclurei plantation. Soil organic matter and nutrients also elevated. It is suggested that the self-sustaining mechanism of the C. lanceolata plantation forest gradually reformed as the proportion of native M. macclurei mixed in the plantation increased. The criteria to determine the proportion of native broad-leaved tree species mixed in C. lanceolata plantations for the purpose of sustainable management should be based on whether the self-sustaining mechanism was reformed and whether the soil nutrient status was improved.

Biomass↗
PubMed2000

[Decomposition process of Chinese fir stump roots and changes of nutrient concentration].

With space as a substitute for time, the changes of the density of stump sapwoods and heartwoods, and the releasing process of major nutrients during the decomposition of Chinese fir stump roots were investigated. The yearly loss rate of the densities of sapwoods and heartwoods was 2.767 x 10(-2) and 2.255 x 10(-2) respectively during decomposition. The contents of N and P in sapwoods and roots decreased continually, while those in heartwoods increased during the first stage of decomposition, and then decreased. The K concentration in stump roots decreased remarkably during first two years, and the content of organic substances decreased during the whole decomposition process. The N, P and K concentrations in roots, were higher than those in stump sapwoods and heartwoods at the beginning of decomposition, but bet content of organic substance was opposite.

Abies↗
PubMed2000

[Bioproductivity of Castanopsis hysrix-Cyclobalanopsis glauca-Machilus pauhoi community in Huitong, Hunan].

Based on the mean DBH measurements of sample trees, the bioproductivity of subtropical Castanopsis hysrix-Cyclobalanopsis glauca-Machilus pauhoi community in Huitong, Hunan province was studied by regression analysis (y = a(D2.H)b). The results showed that the total biomass of the forest was 451.02 t.hm-2, and the component biomass of tree, shrub, liana and litter layer was 426.76, 17.76, 1.80 and 4.70 t.hm-2, respectively. The net production and average production of tree layer were 34.46 and 13.32 t.hm-2.yr-1, respectively.

Biomass↗
PubMed2000

[Dynamics of phenolics content of Chinese fir stump-roots and the rhizosphere soil and it's allelopathy].

Studies on the releasing pattern of phenolics during the decomposition of Chinese fir stump-root and on its allelopathy show that the phenolics contents in stump-roots decreased with their decomposition. Roots had a higher content of phenolics than heart stumps, and edge stumps had the least. The phenolics was released during decomposition, and accumulated in the soils around stump-roots. Pot culture experiment showed that phenolics affected the germination of Chinese fir seeds. The correlation analysis between the density of Chinese fir stump-root and the tree height and base diameter (BD) of its saplings proved that Chinese fir stump-roots had a negative impact on the growth of the next generation of Chinese fir plantations. It is suggested that the traditional operation of Chinese fir plantations should be reformed, and the stump-roots should be cleared from woodland before reforestation.

Phenols↗
PubMed2000

[Cu, Co and Se nutritive value of compound trace elements controlled-release boluses for grazing ruminants].

Twenty cattle with the similar old and weight were randomly divided into two groups for 135 d, while twenty white goats were randomly divided into two groups for 60 d. Each group consisted of ten animals, and the ratio of male and female was same. Each of animals in one group was administered an initial bolus, used as treatment group. In the other group, animals were not administered the bolus, used as control group. In the cattle feeding experiment, five cattle of each group was supplemented feed, and the other five cattles were not supplemented feed. In the goat feeding experiment, all of goats were grazing, and not supplemented feed. At the end of goat feeding experiment, three goats of each group were randomly selected to slaughter. Liver, kidney, spleen, muscle, heart, blood and matter in the rumen were collected to assay for Cu, Co and Se. The results showed that the average daily gain of cattle supplemented and no supplemented feeds in the administered and no administered group was 483.00 g, 302.83 g, 445.84 g and 282.23 g, respectively. There had significantly difference between the administered group and no administered group(p < 0.05). The average daily gain of goats in the administered and no administered groups was 68.83 g and 50.67 g, and significant difference between the two groups (p < 0.01). Administering the boluses improved the contents of Cu, Co and Se in the tissues of goats, significantly.

Animals↗
PubMed2000

[Primary identification of organic compounds in soybean rhizospheric soil on continuous and alternate cropping and their allelopathy on soybean seed germination].

Organic compounds extracted with ethanol (OCEWE) from soybean rhizospheic soil on continuous and alternate cropping at pod-string were identified by gas chromatography-mass spectrometry (GC-MS). The results showed the compounds mainly include organic acids, alcohol, acetone, aldehyde, naphthalene phenyl and furan hydrocarbon, many of which were reported as allelochemcals. Under this experiment condition, OCEWE did not show any allelopathy on soybean seed germination and radicle growth, which might be related with their critical toxicity concentrations. In addition, the relationship between allelopathy and barrier on soybean continuous and alternate cropping was also discussed.

Acids↗
PubMed2000

Embolic events in 93 elderly Chinese patients with atrial fibrillation.

OBJECTIVES: To evaluate the prevalence of embolic events and relevant factors in elderly Chinese patients with atrial fibrillation(AF), and to provide evidence on ways to prevent embolic events. METHODS: Autopsy data from ninety-three continous elderly Chinese patients with AF were analysed. The incidence of embolic events and its relationship to underlying disease, pathologic changes in the heart, and other clinical characteristics were examined. RESULTS: Embolism were observed in 27 of 93 cases, with an incidence of 29.03%. The incidence of embolic events was higher in elderly patients with rheumatic heart disease than those with coronary artery disease, hypertensive myocardiopathy and heart diseases. Patients with chronic AF, with a course of AF > or = 3 years, and those with heart failure or diabetes had a higher incidence of embolic events than those without these complications. There was significant difference in incidence between paroxysmal and chronic AF. Patients with left atrial or ventricular enlargement, mural thrombosis in cardiac chambers, valvular calcification and valvular vegetation also had a higher incidence of embolic events. Oral dipyridamole (75-150 mg/d) or aspirin (50-150 mg/d) showed no definite effects in preventing embolism in some patients. CONCLUSIONS: There was a high incidence of embolic events in elderly Chinese patients with AF. Anticoagulation therapy should be provided to the elderly patients with AF, especially to the patients with risk factors for embolism.

Aged↗
PubMed2000

Interventional treatment of huge hepatic cavernous hemangioma.

OBJECTIVE: To study the methods of interventional treatment of huge hepatic cavernous hemangioma (HCH). METHOD: A total of 14 patients with HCH were treated with lipiodol-ultrafluid (10-15 ml), bleomycin A (PYM 16-32 mg), and gelatin-sponge particles. RESULTS: DSA hepatic arteriography showed multiple vascular lakes in the early arterial phase, so-called "to hang the fruits on the branches", which persisted for a long time. CT scan showed a significant reduction in tumor size in 8 of the 14 patients after the treatment. CONCLUSION: Embolization with lipiodol-ultrafluid, PYM and gelatin sponge particles is one of the best methods for the treatment of HCH.

Adult↗