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Biomedical subjects

S Waikakul

Publications and source records attributed to S Waikakul.

29 records · Page 2Linked to original sources

Prognostic factors for major limb re-implantation at both immediate and long-term follow-up.

We performed a prospective study in 186 patients with a minimum follow-up of two years in order to attempt to predict successful major re-implantation of the upper limb. There were 137 men and 49 women with 24 amputations of the palm, 75 of the wrist, 50 of the forearm, 9 disarticulations through the elbow, and 28 amputations through the upper arm. The degree of injury to the amputated segment and the stump were good predictors of the rate of success and the final outcome. Adequate preservation, contraction of the muscle in the amputated part after stimulation, the level of injury and a smoking habit were fair indicators, but the serum potassium concentration in the amputated segment was the best objective predictor. When it is higher than 6.5 mmol/l 30 minutes after re-perfusion, re-implantation should be avoided. A high systemic venous serum potassium concentration was also found before clinical signs of the re-perfusion syndrome were seen.

Adult↗

Revascularization of degloving injuries of the limbs.

Between 1990 and 1994 a study was carried out of 32 patients who had degloving injuries of the limbs. There were three types of injuries: type I, nine patients with severely damaged skin and subcutaneous tissue; type II, 13 patients whose skin and subcutaneous tissue were moderately damaged, but subcutaneous veins were still identifiable; and type III, 10 patients whose skin and subcutaneous tissue were moderately damaged and venous back flow was observed. The patients in type I were treated by extensive debridement and the flaps were used for free full and split thickness skin grafting. In type II, arterialization of the venous system of the flaps was performed and successful perfusion was observed in nine patients. In type III, venous anastomoses were performed and all had good results. Revascularization of the flaps in types II and III degloving injuries of the limbs gave good results. The raw surface which needed skin grafting was minimized and the course of treatment and morbidity were decreased.

Adolescent↗

Topical analgesics for knee arthrosis: a parallel study of ketoprofen gel and diclofenac emulgel.

The clinical efficacy of the two topical analgesics, ketoprofen hydroalcoholic gel (Fastum gel) and diclofenac emulgel, for osteoarthritis of the knee was studied. There were 85 patients who underwent the trial. They were randomly allocated into 2 groups, the diclofenac group, 42 patients (4 males and 38 females) receiving the diclofenac emulgel at the painfull site four times a day for 4 weeks, and the ketoprofen group, 43 patients (9 males and 34 females) receiving the ketoprofen hydroalcoholic gel four times a day for 4 weeks at the painful knee. Golberg's knee scoring was used to evaluate the patients before the trial, at the end of the first, second and fourth weeks. The ketoprofen group had poorer a score before the trial, however, both groups had improvement in their knee functions, knee score and pain. There was no significant difference between the groups at the end of the study. There was no serious side effect in both groups. Ketoprofen hydroalcoholic gel gave persuasive results in the treatment of knee arthrosis stage I and II.

Anti-Inflammatory Agents, Non-Steroidal↗

Application of problem-based learning in orthopaedic surgery for 5th year medical student at Prince of Songkla University.

Problem-based learning should be continued and extended to more topics. However, the steps and details of the process should be modified to each group of students. The students and tutors should have a period for preparing themselves for the process. The learning media should be improved in quality, quantity and variety to serve almost all of the students.

Education, Medical, Undergraduate↗

Application of freeze-dried amniotic membrane: a control trial at the donor site of split-thickness skin grafting.

Sixty five patients (51 males and 14 females) underwent a control trial of freeze-dried amniotic membrane applied in the form of split-thickness skin grafts over an area from which skin had been surgically removed. The average size of the grafts was 15 x 20 cm. The patients were randomly divided into two groups. In the first group (36 patients), the membrane was applied at the upper half of the wound; in the second group (29 patients), the membrane was applied at the lower half of the wound. The remaining areas of the wounds were covered by antibiotic-impregnated fine-mesh greased gauze. Pain, infection, and the progress of healing were monitored. Covering the wound with the amniotic membrane had good results in terms of pain reduction, but the promotion of healing and the prevention of infection were not demonstrated. Hyperemia and hypertrophic scar responses to the membrane in some cases were considered as disadvantages.

Adolescent↗

Introducing the use of a simple nerve stimulator and locator for intraoperative use.

We found that this simple nerve stimulator which gave a direct current of 4.8 volts, 0.1 to 1.5 mA and 2.0 mA pulse of 60 cycles/min using 9 volts dry cells was useful for peripheral nerve surgery. It is cheap and easy to maintain. Surgeons who are interested in this simple nerve stimulator can adopt this idea themselves or can contact the authors.

Electric Stimulation↗