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Biomedical subjects

S Wade

Publications and source records attributed to S Wade.

67 records · Page 4Linked to original sources
PubMed1982

The effect of lateral visual fixation on response latency to verbal and spatial questions.

The results of several studies have suggested a relationship between lateral eye movements and contralateral hemispheric activation or ipsilateral inhibition. The present study investigated the effects of lateral and central eye fixation on response latency to verbal and spatial questions. Response latencies for verbal questions were significantly longer when subjects fixated to the left or centrally, as compared to the right. On spatial questions, response latencies were significantly longer in the right fixation condition than in the other conditions. The results indicate that visual fixation ipsilateral to hemispheric activation is related to slower problem solving, and suggest that eye movements during cognitive activity may have functional significance.

Cerebral Cortex↗
PubMed1982

Absence of variation in facteur thymique sérique activity in moderately and severely malnourished Senegalese children.

Facteur thymique sérique activity was evaluated in relation to different types of malnutrition in Senegalese children aged 5 to 42 months. They were classified in four groups: controls, moderate malnutrition, marasmus, and kwashiorkor, according to anthropometric measurements and clinical examination. The two latter groups were characterized by very depressed levels of total protein, album in, transferrin and prealbumin, and by high cortisol concentrations. Zinc status was marginal in all children. Facteur thymique sérique activity, determined by the rosette assay, was normal in the malnourished patients suggesting that moderate as well as severe malnutrition is not necessarily associated with depressed levels of circulating thymic hormone. These results are discussed in relation to zinc status and infections.

Blood Proteins↗
PubMed1982

Effect of early postnatal under- and overnutrition on the development of IgA plasma cells in mouse gut.

Development of gut IgA plasma cells was studied in early postnatal under- and overnutrition. Female mice were allowed to suckle in litters of 4, 9 or 20 pups to produce a state of obesity (litter of 4) or protein-energy malnutrition (litters of 20). Litters of nine were considered as control groups. Overfeeding during the suckling period did not change the development and the number of IgA plasma cells of the small intestine. By contrast, the weanling protein-energy malnourished mice had shorter intestines, reduced weight of gut mucosal, muscular and serosal layers and reduced length of villi. However, protein-energy malnutrition, when limited to the suckling period, had no marked effect on the development of IgA plasma cells. A diminished number of these cells was observed only when a more severe and prolonged state of malnutrition was induced.

Animal Population Groups↗
PubMed1975

Prevalence of Dirofilaria immitis in a stray dog population in western New York.

In a survey in 1973 undertaken to determine the prevalence of Dirofilaria immitis in 100 dogs from a public pound in western New York, 2 dogs were found to be positive. Microfilariae of Dipetalonema sp were not present. Hearts and pulmonary blood vessels were dissected for adult worms, and blood samples were examined for microfilariae, using a modified Knott technique. Although adult heartworms and microfilariae have been recovered from wild foxes, coyotes, and wolves in New York, this is the first report of heartworm in domesticated dogs in the state.

Animals↗
PubMedDate not supplied

Explaining drug spending trends: does perception match reality?

Several recent studies have made clear that drug expenditures are rising more rapidly than other health care spending. What has not been clear, however, is how much drug spending is driven by price rather than volume and whether volume increases are appropriate. This DataWatch takes a closer look at the components and drivers of drug spending using large claims databases from managed care and employer-sponsored health benefit plans. In both environments this study found volume, not price, to be the largest driver of drug spending for seven diseases studied. For four of the diseases, we review the clinical issues that may have influenced volume growth.

Centers for Medicare and Medicaid Services, U.S.↗
PubMedDate not supplied

Community concerns.

Explore the source record for details and available documents.

Aged↗
PubMedDate not supplied

Partnership in care: a critical review.

In a comprehensive literature review, the author examines partnership in care between nurses and patients. The article describes the constraints on the relationship, assessing how theory relates to current practice and highlighting the stresses nurses are under as patient attitudes and expectations change.

Attitude to Health↗
PubMedDate not supplied

Synthesis of combinatorial libraries with only one representation of each structure.

A technique of generating libraries in which every compound is displayed only once and all possible combinations are prepared with absolute certainty is presented. The method is based on the stepwise division of a continuous carrier in each step of randomization. Polypropylene membrane and cotton thread were evaluated as potential supports for this approach to library construction. Cotton thread accommodates 400 nmol of test compound per cm, but its mechanical properties limit the dimension of libraries. An alternative combinatorial library of "restructurable toothbrushes" is suggested.

Amino Acid Sequence↗