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Biomedical subjects

S W Jarrett

Publications and source records attributed to S W Jarrett.

3 recordsLinked to original sources
PubMed1997

Ibuprofen-induced aseptic meningitis in rheumatoid arthritis.

OBJECTIVE: To report a case of aseptic meningitis related to ibuprofen ingestion. CASE SUMMARY: We discuss the case of a 56-year-old white man with a history of rheumatoid arthritis and hypertension who became confused, nauseated, and began to vomit within 2 hours of the ingestion of ibuprofen. A diagnosis of ibuprofen-induced aseptic meningitis was made based on the patient's physical and laboratory findings, the quick onset and resolution of symptoms, and his medical history. DISCUSSION: Ibuprofen-induced aseptic meningitis has been most frequently reported in patients with systemic lupus erythematosus. However, there have been reports of this reaction in patients with other underlying disease states. Various nonsteroidal antiinflammatory drugs have been reported to cause this reaction, but ibuprofen is the most common offending agent. A drug-related cause should be considered in any patient who presents with typical meningitis symptoms, such as fever, headache, and stiff neck, that occur within hours of ingesting a drug. CONCLUSIONS: Although persons with systemic lupus erythematosus appear to have an increased risk for this type of reaction, the development of signs and symptoms in other patients warrants the consideration of nonsteroidal antiinflammatory drugs as the cause of aseptic meningitis.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1985

Smallpox eradication: selected management issues.

The eradication of smallpox was dependent on the attainment of a high level of herd immunity during the consolidation and maintenance phases of the eradication program, after mass vaccination effort had reduced the incidence of the disease to a few endemic areas in the world. Immunity was possible through the immunization of susceptible population. Attainment of effective immunization in both large and small countries, with both concentrated and dispersed population settlement patterns, was dependent not only on improved vaccination technology, notably the widespread availability of heat-stable freeze-dried vaccine and the use of the bifurcated needle, but also on the way eradication programs were designed and implemented. This paper will outline important components of the smallpox eradication program, particularly, information management, personnel management, and material resources management. Although they were critical to the eventual success of the program, there has been little consolidated effort to review these management strategies. The paper, to a large extent, concentrates on the eradication programs of Bangladesh, India, and West Africa, given that these come to the forefront in terms of reviewing management strategies in the internationally available literature.

Africa↗