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Biomedical subjects

S W Eubanks

Publications and source records attributed to S W Eubanks.

5 recordsLinked to original sources

Subacute myelomonocytic leukemia--an unusual skin manifestation.

This case report concerns a 44-year-old woman with subacute myelomonocytic leukemia who developed an unusual bullous lesion on her leg. Initially treated as a bacterial ecthyma, this lesion proved to be a specific leukemic infiltrate. We will briefly review myelomonocytic leukemia and the skin findings of the myeloid leukemias.

Adult↗

Perforating folliculitis and psoriasis.

A 51-year-old man with a 10-year history of psoriasis presented with coexistent perforating folliculitis. Several perforating lesions were located within psoriatic plaques. This case is instructive from several viewpoints: (1) it is the second case to appear in the literature, to our knowledge, describing the coexistence of these two conditions; (2) several of the larger lesions resolved during topical therapy with retinoic acid; (3) it demonstrates the histologic difficulties encountered in attempting to classify the major perforating diseases. Possible mechanisms for the development of perforating disease in this patient are discussed, as are the reasons for its apparent response to topical therapy.

Administration, Topical↗

Treatment of multiple keratoacanthomas with intralesional fluorouracil.

A keratoacanthoma is a benign epithelial growth most often found in sun-exposed skin of the elderly. Two main groups of multiple keratoacanthomas have been described: the Ferguson-Smith type and the Grzybowski type. A patient with multiple keratoacanthomas of the Ferguson Smith type is described and the treatment with intralesional 5-fluorouracil is explained. Intralesional therapy with 5-fluorouracil is a safe treatment and may be the treatment of choice for multiple keratoacanthomas and solitary lesions which are difficult to remove surgically.

Fluorouracil↗

The porphyrias.

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Drug-Related Side Effects and Adverse Reactions↗