Ancylostoma caninum: immunization through transfer of sensitized lymphoid cells & their effect on the expulsion and/or destruction of worm burden in Swiss albino mice.
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Ancylostoma↗
Biomedical subjects
S Vyas
Publications and source records attributed to S Vyas.
Expectancy and choice reaction time in early and late adulthood.
Choice reaction time (CRT) was measured for young and elderly adults when both the stimulus and the response, or only the response, or neither the stimulus nor the response had been correctly predicted by the subject. The older adult's CRT exceeded the younger one's by a constant amount in all cases. Implications for the "uncertainty effect" in aging--the disproportionate increase with age of CRT relative to simple reaction time--are discussed.
Adolescent↗
Modulation of selective attention by sequential effects in visual search tasks.
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Adult↗
Some errors of perceptual analysis in visual search can be detected and corrected.
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Adolescent↗
Kaposi's sarcoma of scrotum.
A rare case is presented of Kaposi's sarcoma localized to the scrotum with history, and physical and laboratory findings. Excision of the scrotum with bilateral orchiectomy was performed, with uneventful recovery. Literature is reviewed of Kaposi's sarcoma originating in the male external genitalia.
Aged↗
Preparation, characterization and performance evaluation of neomycin-HSA microspheres.
Human serum albumin microspheres containing neomycin sulphate were prepared using emulsion polymerization and polymer dispersion techniques. The many variables which may affect the shape, size, stability, release of the drug from the microspheres such as internal phase to external phase volume ratio, human serum albumin content, stirring rate, polymer content and stabilizing agent concentration, were studied. Unlike the microspheres prepared by the emulsion polymerization technique, polymer dispersion stabilised microspheres were uniform in size and shape with a narrow range of size distribution. In vitro release of neomycin sulphate from albumin microspheres was studied using the dialysis cell method. The drug release from microspheres followed Q versus (t)-1/2 linear relationship. The in vivo distribution studies on prepared microspheres revealed that the localization takes place preferably in lung tissues, liver, spleen and kidney and is found to be dependent on the microsphere size. On administration of microspheres of 3-6 microns size, approximately 55 per cent of administered drug could be localized in the lungs.
Animals↗
Coexisting chondroblastoma and osteochondroma: a case report.
The coexistence of two different types of benign cartilaginous tumours of bone in the same patient has not been reported in literature. We report a case in which a sixteen-year-old male had a benign chondroblastoma of the proximal left humerus and an osteochondroma of the distal left femur. Both originated at the same time and had a progressive increase in size with growth.
Adolescent↗
Topical diclofenac following excimer laser: effect on corneal sensitivity and wound healing in rabbits.
BACKGROUND: Diclofenac is a nonsteroidal antiinflammatory drug (NSAID) that is widely used systemically and topically. We studied the effect of diclofenac on corneal reepithelialization and corneal sensitivity after excimer laser treatment in rabbits. METHODS: Twelve New Zealand white rabbits were divided into four groups (A, B, C, and D). Groups A and B received diclofenac four times and eight times daily, respectively, following a central 5-millimeter epithelial debridement. Groups C (control) and D (diclofenac four times daily) underwent excimer laser ablation (30-micrometer depth) following manual debridement. Wound healing was compared between groups A and B and groups C and D. Sensitivity was recorded preoperatively and postoperatively 1 to 5 and 14 days in groups C and D until normal values were reestablished. RESULTS: Total time for corneal wound healing and epithelial migration rates was not delayed in any group receiving diclofenac (A, B, and D). Sensitivity after laser ablation reached a minimum of 15% to 20% in both groups C and D by day 2 and returned to normal (100%) by day 8. The decrease in sensitivity between group C, the controls, and group D, receiving diclofenac four times daily, was not statistically significant. CONCLUSIONS: Diclofenac can be used up to eight times daily in the rabbit without causing changes in corneal wound healing or epithelial migration rate. There was no significant, long-term reduction of sensitivity, and recovery was not affected by diclofenac.
Administration, Topical↗