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Biomedical subjects

S V Belov

Publications and source records attributed to S V Belov.

At least 19 recordsLinked to original sources
PubMed2000

[The study of hydrolysis of new lipid-like substrates and trilaurin in monolayers catalyzed with the lipase from Pseudomonas fluorescens].

A simple method for determining the enzymic hydrolysis parameters of lipid-like substrates and trilaurin assembled in monolayers at the water-air interface was suggested. At a surface pressure of 10 mN/m, the initial rates of lipolysis were found to be proportional to the decrease in area of the substrate monolayer caused by the enzymic hydrolysis in a single-compartment Langmuir balance. The kinetic parameters for the hydrolysis of trilaurin and three 1,3-dilaurylpseudoglycerides acetylated in position 2 with an amino acid (phenylalanine, leucine, or valine) catalyzed with lipase from Pseudomonas fluorescens were determined. Unlike models of enzymic hydrolysis that neglect the thickness of the substrate monolayer, our method allows the determination of kinetic parameters in standard dimensions. The values of kcat for the synthetic pseudoglycerides were found to be significantly higher than that for trilaurin, while the values of Km(app) were close. This may be due to the presence of positively charged primary amino groups in the molecules of pseudoglycerides.

Catalysis↗
PubMedDate not supplied

[A new method of high-frequency electrosurgery (coblation technology)].

A new method of electrosurgical intervention, i.e. a high-frequency cold-plasma ablation or coblation-technology, is presented in the article. The method is based on an ionic "bombardment" of the biological tissue at the intervention site, which leads to ruptures of intermolecular cohesions. The method has been widely used in arthrosurgery, cardiosurgery, otorhinolaryngology, spinal surgery and cosmetology. The "ArthroCare" Company (USA) was the first to start developing the discussed method. As for Russia, the Research Institute for Medical Instrument-Making of the Russian Academy of Medical Sciences and Stavropol State Medical Academy are the leaders in promoting the technology in question.

Electrosurgery↗
PubMedDate not supplied

[The technology of high-frequency cold-hot plasma ablation for small invasive electrosurgery].

The mechanism of high-frequency cold-plasma ablation is radically different from thermal impact by high-frequency current in traditional high-frequency surgery. As for the former, the effect is insured due to a local low-temperature molecular disintegration of tissue with the tissue being simultaneously removed from the surgery zone. The technology is based on induction of a stable plasma stratum in the plasma-forming medium by using a high-frequency generator. Kinetic processes occurring in a stationary strongly ionized plasma are under discussion in the paper. The function of the distribution of carriers of the ion containing (Na+, Cl-, K+, Cl-) plasma charge is shown to be close to Maxwellian distribution. The described evaluations of parameters are fundamental criteria for designing a unit that ensures the process of high-frequency cold-plasma ablation. Finally, the stability criteria were analyzed for the low-temperature plasma field.

Chlorides↗
PubMedDate not supplied

[A mathematical model of electrosurgical endoscopical polypectomy].

A mathematical model of electrosurgical polypectomy was suggested. The problem of emitted heat distribution in biological tissues exposed to endosurgical loop electrode was solved. Analysis of the obtained solution made it possible to determine the dependence of the results of electrosurgery on the parameters of the loop electrode and the loop size. Optimization of load performance allowed the efficiency of electrosurgical polypectomy to be increased.

Electricity↗
PubMedDate not supplied

[Electrosurgical device EKhBCh-25-1-C].

The outfit is intended for cutting, coagulation and microcoagulation of the biological tissue by high-frequency current during surgical interventions in stomatology. The outfit ensures smooth control of outlet power. It is fitted out with a timer for automatic time lag of electrosurgical exposure. The generator is triggered by pressing the pedal or push button of the electrode holder. The outfit is also equipped with a kit of instruments. A short technical specification of the outfit is given.

Dentistry, Operative↗
PubMedDate not supplied

[Development of a high-frequency electrosurgical endoscopy apparatus].

A brief analysis has been made of the basic operational features of the high-frequency electrosurgical endoscopy apparatus (HFEA). Recommendations for choosing the output parameters are given, the solution of the problem of designing HFEA for endoscopy was considered by using the "Endotome-I" apparatus as an example.

Electrodes↗
PubMedDate not supplied

[Electrical safety of endoscopic equipment].

The article considers in detail the problems affecting the safety of the patients and the medical personnel during endoscopic examinations, gives practical recommendations both to the endoscope makers and users.

Electric Injuries↗
PubMedDate not supplied

[Effect of high-amplitude electrical impulses on the strength of the coagulative adhesion of the blood vessels].

Strength of coagulative commisure of the blood vessel tissues in their coagulation with high-frequency current can be increased after additional action of high-amplitude electrical pulses. A comparative test of commisures tensile strength confirmed its possible increase by 1.6--1.7 times when vascular tissues were preliminarily subjected to the action of short high-amplitude electrical pulses.

Animals↗
PubMedDate not supplied

[New models of forceps for bipolar coagulation].

Operations on the brain require an optimum coagulation effect to be produced by forceps for bipolar coagulation. New forceps models are described in which the elimination of heat from the operating ends is considerably improved by making the whole forceps of copper and providing intermittent supply of high-frequency current to it. As a result the coagulation effect is distinguished by slight necrosis of the tissues adjoining the ends of the forceps and no sticking of these tissues to these ends.

Brain↗
PubMedDate not supplied

[Improvement of effectiveness of high frequency electrosurgical equipment].

The paper summarizes the results of the activities of the All-Russian Research Institute of Medical Industry on the development of electric stimulating equipment for anesthesiology and the experience in its application. It also deals with electrostimulations, such as transcranial (transcerebral) electroanalgesia, transdermal (transcutaneous) electroneurostimulation, epidural (peridural) electrostimulation, perineural electric neurostimulation, testing electrostimulation of peripheral nerves in making regional anesthesia, electric neurostimulating testing of neuromuscular transmission. The developed monofunctional Delta-101, Delta-102, Delta-301, Synapse-1 electric neurostimulators and a polyfunctional Anestim-PF apparatus used in anesthesiological care and other related medical fields.

Electrodes↗