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Biomedical subjects

S Ueno

Publications and source records attributed to S Ueno.

At least 361 records · Page 20Linked to original sources
PubMed1986

[Increased activity of sympatho-adrenomedullary system and decreased renal dopamine receptor content after short-term and long-term sodium loading in rats].

UNLABELLED: We investigated the effects of short-term and long-term sodium loading on the sympathoadrenomedullary system and renal dopamine receptor. Male Wistar rats (n = 30) were raised drinking 1% NaCl for four weeks. Urinary norepinephrine and epinephrine excretion (UNE and UE) were measured before and 1, 2, 4 weeks after sodium loading by the use of high pressure liquid chromatography with fluorescence spectrophotometer. Renal plasma membranes were prepared by the ultracentrifugation method, and maximal binding capacity (Bmax) and dissociation constant (Kd) of renal dopamine receptor were determined by Scatchard analysis using 3-H-spiperone. RESULTS: Sodium loading caused a slight but not significant decrease of free UNE after 1 and 2 weeks then clear increments of total (free + conjugated) UNE, free UE and total UE after 4 weeks. Bmax of renal dopamine receptor did not change after 1 and 2 weeks but significantly decreased after 4 weeks (before: 535.9 fmol/mg X protein, after 4 weeks: 327.2 fmol/mg X protein). Kd of renal dopamine receptor slightly elevated 1 week after sodium loading and then returned to the initial level. CONCLUSION: These data suggest that short-term sodium loading may suppress the sympathetic activity, but long-term sodium loading may increase the activity of the sympathoadrenomedullary system with the decrease of renal dopamine receptor concentration. Increased catecholamines and decreased renal dopamine after long-term sodium loading may contribute to sodium-dependent hypertension.

Adrenal Medulla↗
PubMed1986

[Role of renal dopamine receptor in the pathogenesis of hypertension after sodium loading].

UNLABELLED: The purpose of this study is to clarify the role of renal dopamine receptor in the pathogenesis of salt-dependent hypertension. Male Wistar rats were raised under three different conditions, control, 1% NaCl loading (NaCl) and 1% NaCl plus metoclopramide with a dose of 1.5 mg/kg daily (MC), for 2 weeks. Then, renal plasma membranes were prepared by ultracentrifugation method, and maximal binding capacity (Bmax) and dissociation constant (Kd) were determined by Scatchard analysis using 3H-spiperone. And plasma aldosterone and prolactin concentration in these three groups were measured by radioimmunoassay. RESULTS: Systolic blood pressure measured tail-cuff method significantly elevated in MC group, but not control and NaCl group. Bmax of renal dopamine receptor was 535.9 +/- 85.0 fmol/mg protein, 594.9 +/- 159.3 fmol/mg protein, 529.1 +/- 166.1 fmol/mg protein, in control, NaCl and MC group, respectively. Kd of renal dopamine receptor in NaCl group was significantly lower than control (p less than 0.05). Renal dopamine contents of NaCl and MC group were lower than control. There was a negative correlation between renal dopamine content and Bmax of renal dopamine receptor in NaCl group (r = -0.95, p less than 0.02). In MC group, plasma aldosterone concentration was slightly higher than control and NaCl group, but there was no differences in plasma prolactin concentration among these three groups.

Aldosterone↗
PubMed1986

Cytochemical demonstration of acid phosphatase activity in the pineal organ of the rainbow trout, Salmo gairdneri.

Activity of acid phosphatase (ACP) was investigated cytochemically in the pineal organ of the rainbow trout, Salmo gairdneri. Intense reaction product for ACP activity was observed in lysosomes varying in size and shape and in endoplasmic reticulum associated with the Golgi complex of the pineal photoreceptor and supporting cells, vascular endothelial cells, and macrophages inhabiting pineal lumen, parenchymal epithelium and perivascular spaces. This localization of ACP is discussed with particular reference to the capacity for lysosomal digestion in a pineal organ combining photoreceptive and secretory functions, and lacking a blood-brain barrier, as holds true for the pineal of the rainbow trout. Taking advantage of its capacity for endocytotic uptake and lysosomal digestion, the pineal organ of the rainbow trout may serve as a barrier between the blood circulation and the cerebrospinal-fluid compartment. Furthermore, the macrophages may be considered as an essential component in pineal function of fish.

Acid Phosphatase↗
PubMed1986

Radiologic demonstration of Caroli's disease: a case report.

Since the first report by Caroli et al., there have been several reports dealing with Caroli's disease or multiple communicating cysts of the biliary tree. Recently, the usefulness of computed tomography, endoscopic retrograde cholangiopancreatography, ultrasonography, and radionuclide scintigraphy have been emphasized for evaluation of this condition. This report describes a case of Caroli's disease and emphasizes the value of ultrasonography in the evaluation of this condition.

Bile Duct Diseases↗
PubMed1986

Peripheral ameloblastoma resembling a papilloma: report of case.

A case of peripheral ameloblastoma in the mandibular gingiva of a 42-year-old man has been reported. The tumor was clinically diagnosed as a papilloma and excised under local anesthesia. There was no connection with the alveolar bone. Histologically, the parenchyma was similar to that of enamel organ and basal cell carcinoma. The epithelial cords were continuous with the mucosal epithelium. There was no recurrence during a two-year period.

Adult↗
PubMed1986

Electrocardiograms recorded from the body surface of the carp, Cyprinus carpio.

The electrocardiograms (ECGs) in five kinds of bipolar leads were recorded from the body surface of the carp under water. Each component constituting the ECG wave could be detected by the present method. The potentials of the ECGs recorded by the present method were relatively small, the values being 2-64 microV. The electrical axis in most carp was directed toward the right lateral side.

Animals↗
PubMed1986

A clinicopathologic study of ameloblastoma.

One hundred four ameloblastomas, 97 in the mandible, five in the maxilla, and two in peripheral locations, were studied. A consistent correlation between the age of the patient and the radiographic or histologic type of mandibular ameloblastoma was observed. There was a tendency for ameloblastomas of the follicular type to show a multilocular or soap bubble appearance and for those of the plexiform type to show a unilocular appearance. Recurrent ameloblastomas had a predominantly multilocular appearance. Histologically, the ameloblastomas in the maxilla were of the follicular type.

Adolescent↗
PubMed1986

Silicone oil particles trapped in the subretinal space: complications after substitution of the vitreous.

Silicone oil particles trapped in the subretinal space, following total replacement of the vitreous by oil, were found in the aphakic eye of a 51-year-old man. The eye had been operated on two times for retinal detachment in other institutes which resulted in a grade D-1 proliferative vitreoretinopathy. The silicone particles resembled beads and were slightly mobile among subretinal strands by changing the eye position. The particles freely moved into the vitreous cavity through a retinotomy site and were removed with the silicone from the vitreous cavity because of ocular pain. Subconjunctival granulation was removed and histological examination showed silicone oil particles in the vitreous cavity, and cellular infiltration.

Cataract Extraction↗
PubMed1986

Two adult familial cases of selective hypoaldosteronism due to insufficiency of conversion of corticosterone to aldosterone.

A 57-year-old woman (case 1) and her daughter aged 29 (case 2) with hyperkalemia exhibited subnormal plasma aldosterone (ALD) in the face of elevated plasma renin activity. Their physical findings were normal. Their arterial blood gas analysis showed that metabolic acidosis and renal function of these cases were slightly impaired. Urinary 17-OHCS and 17-KS excretions in these cases were normal. Baseline levels of corticosterone (B) and 18-hydroxycorticosterone (18-OH-B) were clearly elevated. Plasma deoxycorticosterone (DOC), B and 18-OH-B as well as cortisol remarkable increased after ACTH injection, but the increase in plasma ALD was very small. Angiotensin II infusion in case 1 resulted in a clear rise in plasma 18-OH-B but in slight depletion of B, and no increase in ALD. 9-alpha-fludrocortisone acetate treatment was performed in case 1. Serum potassium was normalized and blood pressure elevated from 82/52 to 120/78 mmHg. Arterial blood gas analysis was corrected. We concluded that these two cases with subnormal plasma ALD and hyperreninemia may exist as a congenital and familial abnormality of the final step of aldosterone boisynthesis due to the impairment of the conversion of B to ALD.

Adrenocorticotropic Hormone↗
PubMed1986

Automatic reregistration for correction of localized misregistration artifacts in digital subtraction angiography of the head and neck.

A new automatic computer program, to remove misregistration artifacts secondary to motions such as rotation, contraction and relaxation of the body, has been developed. This program is called automatic reregistration and consists of determination of distortion vectors of corresponding segments of the mask and live images by detection of the peak value of two-dimensional cross correlation, followed by obtaining distortion vectors of other pixels through interpolation. Shift of the coordinate of the distorted live image is subtracted. Clinical evaluation of this new program, in comparison with already developed remasking and manual reregistration, have proved that some misregistration artifacts, uncorrectable by the latter two methods, have been removed to some extent. The new program has proven to be clinically useful.

Angiography, Digital Subtraction↗