Search PubMed⌕ Search

Biomedical subjects

S Ucchino

Publications and source records attributed to S Ucchino.

At least 37 records · Page 2Linked to original sources
PubMed1980

[The sick sinus syndrome. Our experience with permanent electrostimulation].

Our study concerns 20 patients affected by "Sick Sinus Syndrome", these has been observed in our Coronary Care Unit during the period 1-7-1976 to 26-4-1979. All patients has been submitted to an electrophysiological study of the conduction system; of those only 16 has been treated with a permanent PMK, the other 4 with medical therapy. Our study's results underline the problematic nature of the "Sick Sinus Syndrome" and underline its etiopathogenetic, diagnostic and therapeutic aspects.

Adult↗
PubMedDate not supplied

Factors associated with apoptosis in symptomatic and asymptomatic carotid atherosclerotic plaques.

The aim of this study was to investigate the differences that are present between apoptosis in symptomatic (with symptoms of cerebral ischemic attack) and asymptomatic carotid atherosclerotic plaques. The apoptotic process in macrophages and smooth muscle cells was evaluated. Cellular markers and products of immune cells in symptomatic and asymptomatic atherosclerotic plaque and endoarterectomy specimen were analyzed by immunohistochemistry. No statistically significant differences were present regarding the mean SMC actin-positive area. Using double staining of alpha-smooth muscle actin and TUNEL techniques, the number of smooth muscle cells in apoptosis was statistically higher in symptomatic plaque as compared with asymptomatic plaque. Statistically significant differences (p=0.009) were also found in the CD45-positive cells in the inflammatory infiltrate. The CD68-positive macrophages showed statistically significant differences (p=0.0001). Similarly, the double staining with CD68 and TUNEL revealed that apoptotic macrophages were mainly present in asymptomatic plaques rather than symptomatic plaques. Statistically significant differences (p<0.001) were found in the Bcl-2 expression, with higher values in asymptomatic plaques. Our data showed that the increase of the inflammatory cells contributes to plaque instability and that death due to apoptosis of smooth muscle cells in symptomatic plaques could contribute to their destabilization and explains their tendency to fracture.

Aged↗
PubMedDate not supplied

The treadmill test in the assessment of peripheral arterial occlusive disease.

Results of a study using the treadmill test on 32 patients with peripheral Fontaine's stage II arterial disease are described. The aim of the study was to evaluate the utility of the test in assessing useful information concerning the site of the lesion. Patients were divided in three classes depending on the arterial segment involved (iliac-femoral, femoro-popliteal, associated lesions) as resulted from the velocimetric and angiographic evaluation. Ankle pressure and WI, at rest and after stress test, PFWD and RT were evaluated. The authors conclude that data achieved with the dynamic test are related to the arterial involvement, allowing to differentiate obstructive and stenotic lesions, but do not give information concerning the site of the lesion. Nevertheless it is a valuable means of highlighting arterial lesions well compensated at rest and with normal pressure values.

Aged↗
PubMedDate not supplied

[Neurinosarcoma of Vater's papilla. Apropos of a case].

Neurinosarcoma of Vater's ampulla is rarely observed. A case is presented in which the tumour did not occlude the ampulla and was thus detected intraoperatively. The head of the duodenum and the pancreas were ablated. Histological examination showed a fasciculated neoformation, in which the individual fasciculi ran parallel to or crossed each other. The nuclei displayed distinct atypical pictures. The little cytoplasm there was could only be clearly made out in areas involved in oedematous dissociation.

Ampulla of Vater↗
PubMedDate not supplied

[Carotid thromboendarterectomy. The authors' personal experience].

Carotid endarterectomy is the most frequently employed surgical intervention in the treatment of strokes due to atherosclerosis obstruction of the blood flow in extracranial carotid district. The presence of cerebrovascular clinical symptoms is accepted indication for surgical treatment. For the patients without symptoms there is, however, not yet a complete agreement on the treatment modalities. The authors believe that, due to the low morbidity and mortality of carotid endarterectomy, a surgical approach can be used in patients in which is present a degree of stenosis > 75% and, moreover, in patients where the degree of stenosis is > 50%, but in which the atherosclerotic plaque is non homogeneous due to the presence of ulceration or hemorrhage. Non invasive ultrasonic techniques constitute the mainstay of the diagnostic procedures for carotid artery disease and in recent years they have led to improved sensitivity and ability in differentiating between the operable carotid stenoses and the inoperable obstructions. With these techniques it is possible to arrive to a 90% diagnostic accuracy. Also the recently introduced angio-RM has comparable results, but the high costs do not make it possible to use it in screening procedures. Many doubts are present regarding the possibility of evaluating the occurrence of neurologic deficits during the surgical procedures. Local anaesthetic techniques are somewhat popular among vascular surgeons in that they allow an immediate evaluation of the neurologic activity of the patients during surgical treatment. However reports have been published in the literature of neurologic deficits arising after the period of test occlusion.

Aged↗
PubMedDate not supplied

[Injury of the popliteal artery & the popliteal branches: analysis of 31 consecutive cases].

In complex traumas of lower limbs it is fundamental the reducing of the time of ischemia to reduce the number of failures in repairing surgery and the percentage of the demolishing of necessity surgery. The experience of the authors is based on 31 complex traumas of lower limbs with distal vascular injuries to Hunter's canal, which were associated to bone, nervous and muscular lesions. In total we are treated 37 vascular injuries by interposition of venous autografts in 37 cases, lateral pacth in one case ant suture T-T in two cases. The protection of the reconstructed vases, in case of a concomitant loss of substance, was entrused to microvascular flaps for 7 times latissimus dorsi, iliac crest and fascio-cutaneous for 5 times posterior reversed with distal baset and for three times antero-lateral, which in three cases of them needed successively a dermoepidermic grafts. The bone injuries, which were treated by external fixation, intramedullary nailing, plate and screws, just in two cases became worse in pseudoarthroses and just in one in osteomyelitis. The reparation of nervous injuries had bad results just in two cases. The percentage of saving of the limb it was about 83.9%.

Female↗
PubMedDate not supplied

[Gynecomastia].

Gynaecomastia is a benign enlargement of the male breast commonly occurring in healthy adolescent boys and in adults (50 to 80 years old). It is a source of cosmetic and psychologic problems. The secondary forms usually require no therapy other than the removal of any identified inciting cause. Most of the idiopathic forms last only a few months and then gradually disappear. In secondary gynaecomastia and idiopathic forms present for more than 12 months a medical hormonal treatment often fails and the only therapy is surgery consisting in a subtotal subcutaneous mastectomy. In the last years the surgical treatment is often completed with suction lipectomy: this procedure reduces the surgical traumatism. The authors present their experience concerning 47 patients: 27 were surgical treated with subcutaneous subtotal mastectomy and 18 had an abjunctive liposuction treatment with good results.

Adolescent↗
PubMedDate not supplied

[Clinical considerations of cases of biliary ileus].

The authors report 6 cases of gallstone ileus due to cholecystoduodenal fistula. In 4 patients a simple enterolithotomy was performed, while in one case the enterolithotomy was associated to cholecystectomy and duodenal suture; in the last patient it was associated to cholecystectomy and gastric resection. Only one death was registered among the cases treated with enterolithotomy. The authors believe that the severity of the pathology, generally combined with other important diseases, needs an eclectic treatment depending on the patient status.

Aged↗