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Biomedical subjects

S UDENFRIEND

Publications and source records attributed to S UDENFRIEND.

At least 19 recordsLinked to original sources
PubMed1963

COLLAGEN-LIKE PROTEIN IN HUMAN PLASMA.

Human plasma contains hydroxyproline in a bound form that is nondialyzable, is precipitable with the usual protein precipitants, can be extracted with hot trichloroacetic acid, and is released on hydrolysis in 6N HCI. These properties resemble those of collagen and suggest that small amounts of this connective tissue protein (3 to 5 mg per 100 ml), or a very large peptide derived from it, normally circulate in the blood. The identification and analysis of hydroxyproline in hydrolyzates of plasma protein were based on isotope-dilution procedures.

Blood Chemical Analysis↗
PubMed1963

NOREPINEPHRINE AND 3,4DIHYDROXYPHENETHYLAMINE TURNOVER IN GUINEA PIG BRAIN IN VIVO.

By administering C(14)-la-beled tyrosine or H(3)-labeled 3,4-dihy-droxyphenylalanine to guinea pigs it has been possible to achieve sufficient labeling of the norepinephrine and dopamine in the brain to permit measurement of their turnover rates. The half-life of brain dopamine was about 2.5 hours. The half-life of norepinephrine was about 4 hours, suggesting a rate of synthesis of at least 0.03 to 0.04, microg/g per hr or 2.4 microg/day for the whole guinea pig brain.

Animals↗