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Biomedical subjects

S Toyoda

Publications and source records attributed to S Toyoda.

At least 73 records · Page 4Linked to original sources
PubMed1985

Physiological factors controlling release of enterokinase from rat enterocytes.

The quantitative release of enterokinase from isolated rat enterocytes following treatment with taurocholate-taurodeoxycholate, papain, chymotrypsin, elastase, carbamylcholine, and cholecystokinin-octapeptide was examined. Alkaline phosphatase and lactate dehydrogenase activities were evaluated simultaneously to check for specificity. Bile salts promoted a concentration-dependent release of all enzymes. Concomitantly, bile salts also led to cell destruction in proportion to the amount of enzymes released. Proteases caused the release of enterokinase and alkaline phosphatase with no concomitant increase of lactate dehydrogenase or cell lysis. At equal concentrations, papain released more enzymes than chymotrypsin and elastase. Chymotrypsin and elastase, however, led to higher ratios of enterokinase to alkaline phosphatase found in the media and suggested a selective release of enterokinase (EK) over that of alkaline phosphatase. Bile salts and pancreatic proteases together seem to have an additive effect of the release of EK. Carbamylcholine and cholecystokinin-octapeptide had no effect on enzyme release. These results suggested that pancreatic proteases are involved in the release of enterokinase by a selective action. Bile salts may also play a role through a nonselective detergent effect.

Alkaline Phosphatase↗
PubMed1981

Non-traumatic middle meningeal aneurysm and angioma in a child.

A 9-year-old boy having bronchial asthma showed fluctuation of his mental state for 14 days. EEG showed multiple spikes or irregular spike and wave complex bursts, the focus being in the left occipital region, and he was diagnosed as prolonged partial complex status epilepticus. Skull radiograms revealed the presence of radiolucent areas in the left parietal region and cerebral angiography showed a pear-shaped aneurysm and angioma in the distal part of the middle meningeal artery. Nontraumatic aneurysm of the middle meningeal artery has been rarely reported; only the reports on 2 old women with Paget disease are available now. The authors' case is the first child case.

Aneurysm↗
PubMed1981

[Flange technic].

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Dental Impression Technique↗
PubMed1979

Role of thymectomy in the surgical treatment of myasthenia gravis.

Of the 26 patients with myasthenia gravis undergone thymectomy, 11 cases had either benign or malignant thymoma as judged not only by hitological examination but also by their clinical and operative findings. Age of initial onset ranged from 13 to 64 years old. Fifteen out of 26 (58 per cent) benefited from thymectomy. Duration of the symptom from the onset to the operation and the presence or absence of the thymoma are not related to their outcome. Benign or malignant nature of thymoma should not be determined by histological examination alone but by combined evaluation of clinical and operative findings. Serial studies of serum immunoglobulin levels before and after thymectomy suggested that this disorder could be associated with humoral antibody (IgG). HLA typing of the patients with myasthenia gravis did not indicate the presence of any specific antigens.

Adolescent↗