[A d-lymphoproliferative disorder characterized by lymphocytes with combined T and B surface markers, and with IgA k M component in the serum (author's transl)].
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Biomedical subjects
Publications and source records attributed to S Tognella.
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Treatment of human perypheral blood lymphocytes with phytohaemagglutinin (PHA), for 30 min and for 72 h, increases their ability to form E-rosettes. Possible interpretations of the phenomenon are discussed.
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In 32 patients with Hodgkin's disease the electrophoretic mobility of peripheral blood lymphocytes and, at the same time, some clinical, hematological, and immunological parameters of the disease were determined. The mean mobility of lymphocytes was normal; nevertheless, the lymphocytic mobility of 8/32 patients was significantly decreased. No correlation with clinical, hematological, and immunological parameters of the disease was detected. However, the functional deficiency of hodgkinian T lymphocytes seems to play a role in their abnormal electrophoretic behaviour. In 9 out of these 32 patients the electrophoretic mobility of peripheral erythrocytes was also determined. The average mobility was significantly (P less than 0.05) decreased. No correlation with clinical, hematological, and immunological parameters nor with electrophoretic mobility of lymphocytes was detected.
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