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Biomedical subjects

S Terashima

Publications and source records attributed to S Terashima.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Renal tubular impairment after surgery].

It is well known that acute renal failure (ARF) after surgery has a high mortality rate. The purpose of this paper is to clarify the renal tubular damage following surgery. Urinary beta 2 microglobulin (u-BMG) and urinary N-acetyl-beta-D-glucosaminidase (u-NAG) activities, thought to be the sensitive indicators of renal tubular impairment, were measured in 48 patients treated surgically in our clinic. Three out of 48 patients developed ARF. Remaining 45 showed normal values in conventional renal function tests, while u-BMG and u-NAG revealed abnormally high levels in many cases. Bleeding amount during surgery, operative time, postoperative complications, especially circulatory shock, and preoperative hypotention were the factors which correlated closely to the elevation of u-BMG and u-NAG. Administration of urinastatin prevented the u-NAG elevation postoperatively, while it had no effect on u-BMG.

Acetylglucosaminidase↗
PubMed1988

A case of left ventricular aneurysm of uncertain etiology presenting as ventricular tachycardia.

A case of a 59-year-old Asian male with several episodes of syncope and palpitation is reported. Electrophysiologic study disclosed that sustained ventricular tachycardia was induced by programmed electrical stimulation at the right ventricular apex. The electrogram in the left ventricular aneurysm showed delayed activities and the fastest depolarization. Entrainment was observed by faster pacing. Left ventriculography showed a large aneurysm and normal coronary arteries. Congenital left ventricular aneurysm is the most likely clinical diagnosis given the lack of past history of chest pain, myocarditis, cardiomyopathy, etc. Congenital aneurysm which presents as ventricular tachycardia is very rare, and has never been reported in an Asian. Medical management has thus far been successful.

Bundle-Branch Block↗
PubMed1987

Substance P-like immunoreactive fibers in the trigeminal sensory nuclei of the pit viper, Trimeresurus flavoviridis.

Substance P-like immunoreactive nerve fibres were located in the trigeminal sensory system of the infrared-sensitive snake, Trimeresurus flavoviridis, using the immunohistochemical method. There are two trigeminal sensory systems in the medulla of this animal: the descending nucleus and the lateral descending nucleus. The descending nucleus is equivalent to the trigeminal spinal nucleus in other vertebrates, and the lateral descending nucleus is a special trigeminal sensory nucleus belonging to the infrared sensory system. In the present study we determined that the lateral descending nucleus is completely ensheathed by large numbers of substance P-like immunoreactive fibers. The distribution of these fibers seems to be similar to that of the thin vagal unmyelinated fibers, rather than to that of the thick trigeminal myelinated fibers. More substance P-like immunoreactive nerve fibers were observed in the lateral descending tract than in the descending tract. Almost no dense substance P-like immunoreactive fibers were found in these tracts rostral to the lateral descending nucleus or rostral to the subnucleus caudalis of the descending nucleus. The substance P-like immunoreactive fibers in the lateral descending tract extended to those of Lissauer's tract of the spinal cord, and the substance P-like immunoreactive fibers surrounding the Lissauer's tract were similar in appearance to those of the lateral descending nucleus. This nucleus seems to have developed from the elements existing in Lissauer's tract, and also to have a similar modulating function. The primary nucleus of the infrared sensory system is the most substance P-like immunoreactive nucleus in the trigeminal sensory system of this animal. Even in the trigeminal sensory system, substance P-like immunoreactive fibers seem not to be related solely to the nociceptive sensation.

Animals↗
PubMed1987

Elastic properties and beta-sheet structure of connectin threads.

Connectin is a very long and flexible protein of striated muscle, linking myosin filaments to z discs in a sarcomere. Isolated native connectin in solution frequently forms elastic threads upon concentration of the solution, by side-by-side association of molecules. An X-ray diffraction study was performed to examine the presence of beta-sheet structure in artificially prepared threads. The elastic properties of such threads were measured at various temperatures. Negative temperature dependence of the elastic coefficient suggests that the elasticity of connectin threads is due to deformation of the three-dimensional structure and not to rubber-like behavior.

Animals↗
PubMed1984

Vagal afferent C fibers projecting to the lateral descending trigeminal complex of crotaline snakes.

The primary vagal axons and terminals in the lateral descending trigeminal complex (dlv-DLV complex) in crotaline snakes were studied following HRP injections into the vagal nerve. Labeled fibers and terminals were found in the marginal neuropil, which was made up entirely of unmyelinated fibers, i.e., C fibers. The general features of vagal input to the dlv-DLV complex in snakes with infrared sensitivity (Boidae and Crotalinae) are discussed.

Afferent Pathways↗
PubMed1983

Static response of infrared neurons of crotaline snakes--normal distribution of interspike intervals.

Background discharges (static responses) of warm fibers in the pit organs (infrared receptive organs) of two species of crotaline snakes were recorded at various temperatures (water, 18-33 degrees C; air, 19-28 degrees C). Mean interspike intervals (means), standard deviations (SD), and coefficients of variation (CV) were calculated, and the goodness of fit of interspike interval histograms to a corresponding normal distribution (i.e., one having the same mean and SD) were tested. Means, SD, and CV were smallest at a certain temperature, which might be the optimum receptor temperature for the species. More than half of the histograms (22/42 for water, 7/10 for air) showed a normal distribution at a significance level of 0.01. This suggests that the spike intervals generated at the spike initiation site are constant, with some random error. Background discharges of three pure infrared secondary neurons from the lateral descending nucleus were analyzed in the same way and compared to the peripheral discharges. There were no histograms with a normal distribution in these central neurons, which might indicate that the constant interspike intervals which appear in the primary afferent fibers are not utilized for information processing at this level but occur only as part of a receptor mechanism which is still unknown. The discharge patterns of primary afferent fibers are also discussed in relation to the known discharge patterns of cold fibers in other animals.

Action Potentials↗
PubMed1981

Python pit organs analyzed as warm receptors.

The infrared receptor neurons of Python reticulatus pit organs were all found to have bimodal sensitivity, responding to both infrared and touch stimuli with fairly rapid adaptation. The majority (22 of 29 neurons) had no background discharges at any temperature between 20 and 33 degrees C. The receptive areas were 150-250 micrometers in diameter and identical for both modalities. There was only one receptive area for each neuron. These facts suggest the possibility that some kinds of temperature sensitive neurons can also function as touch neurons and vice versa, not only in this species, but also in other animals.

Animals↗
PubMed1981

Crotaline pit organs analyzed as warm receptors.

Afferent impulses from single-fiber preparations of the trigeminal nerve in Agkistrodon blomhoffi brevicaudus were recorded during steady and dynamic temperature stimulation of the sensory membrane in the facial pit. The thermoreceptors of the pit showed high sensitivity to the rate of change in receptor temperature. Changing the heat capacity of the pit membrane (a drop of water in the pit in the case of the laser and halogen lamp, and a drop of water covered by a plastic film in the case of flowing water) changed the pattern of response. When the heat capacity of the pit membrane is increased, responses approach those obtained in other warm receptors. The spatial gradient theory of Williams, whereby a reversal of heat energy flow is supposed to produce a reverse of response, was shown to be inapplicable to the pit receptors. Reversal of heat energy flow in the pits produced neither off-silence nor depression of response, and therefore direction of heat flow is not an important component of the stimulus for these receptors.

Afferent Pathways↗