Quenching effects of various compounds on fluorometric assay of tryptophan.
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Biomedical subjects
Publications and source records attributed to S Takeda.
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In casting of high-fusing alloys such as cobalt-chrome and nickle-chrome alloys, the reaction between the investing mold and high-fusing molten alloys suffers the disadvantage of the scale formation. The various coating materials are used to prevent the scale formation. The experiments have been carried out to prove the effectiveness of seven commercialized coating materials. And the reaction between the coating materials and high-fusing molten alloys was analyzed by X-ray diffractometer. Results were as follows: 1) The refractory compositions of seven commercialized coating materials were composed of alpha-quartz (SiO2), zircon (ZrSiO4) and zirconium oxide (ZrO2). 2) Dainainvest (Ohara) mainly containing zircon indicated the reduction in surface roughness due to coating. Although zircon was slightly observed on the cast surface, the product of reaction was not detected. 3) Liquid investment (Nobilium) and Paint investment (Shofu) having about equal amounts of alpha-quartz and zircon showed as reduction in surface roughness as Dainainvest. The product of reaction was not observed and the cast surface was smooth. 4) Quick request (Shiken), Pre-coat (Niranium) and Ethymay B (Kamemizu) composed of alpha-quartz had not appreciably effectiveness. The cast surface was rough due to production of picrochromite (MgCr2O4) and eskolaite (Cr2O3)in the reaction between molten alloys and coating materials. 5) Hi-coat with zirconium oxide did not point out the advantage in spite of high refractory composition and showed little reduction in surface roughness due to coating.
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Attempts were made to attain a semiquantitative evaluation of therapeutic effectiveness of lung cancer by scintiscoring of the liver as well as the tumor lesion. A relative counting ratio of tumor to liver was computed, and this was found useful: in areas of active tumorous growth, higher ratios were obtained. The ratios returned to the control levels following irradiation with or without an anti-inflammatory regimen including prednine. The technic is simple, and yet invaluable especially when the tumor locates in the mediastinum escaping from radiological detection. Satisfactorily frequent repetition would be competent enough in early diagnosis of developing radiation pneumo-mediastinitis and regrowths in the mediastinum and fibrotic abnormal shadows as well. The principle would be best rewarded by use of a whole-body scanner equipped with a digital computer.
Intracellular localization of gallium-67 was investigated in Morris hepatoma-7316A and Shionogi mammary carcinoma-115 cells by the cell fractionation method 48 hr after an intraperitoneal injection of the nuclide. When lysosomes were purified from both tumors by discontinuous sucrose density gradient centrifugation, they had a strikingly high relative specific activity of the nuclide. From these results it was confirmed that gallium-67 is concentrated most specifically in the lysosomes of both tumor cells, which consist chiefly of phagolysosomes and can engulf only limited amount of foreign materials such as Triton and gallium-67.
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A case of cavernous hemangioma which developed in the parietal convexity is reported. Angiography reveals that the mass is located extra-axially in the parietal convexity and the middle meningeal artery feeds the tumor. The feature of tumor stain is pooling or laking of contrast medium which is partially visualized even 10 minutes after injection of contrast medium. CT findings are almost identical to those of meningioma.
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Coagulation studies were done on 78 consecutive cases of obstructive jaundice with or without biliary tract infection. Among 26 cases with biliary tract infection 20 cases showed no bleeding tendency but remarkable hypercoagulability with decreased fibrinolytic activity. Other six cases developed diffuse bleeding tendency in addition to the signs of hypotension and multiorgan dysfunction such as oliguria, respiratory distress and mental confusion. Most showed marked coagulation defects characterized by thrombocytopenia, decreased fibrinogen, antithrombin III and plasminogen levels and narrowing of maximal amplitude in thrombelastogram as well as the increase of fibrin degradation products and positive soluble fibrin monomer complexes. All except one died and three cases were autopsied. In two cases postmortem examination revealed multiple fibrin thrombi in lungs and other organs. A cause of the development of bleeding tendency in obstructive jaundice presently observed may likely to be due to the occurrence of disseminated intravascular coagulation (DIC), i.e. hypercoagulability caused by the biliary tract infection is responsible.