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Biomedical subjects

S Tahara

Publications and source records attributed to S Tahara.

At least 91 records · Page 5Linked to original sources
PubMed1990

[A case report of coronary artery bypass surgery (3-SVG) in 80-year-old woman with acute respiratory failure].

A successful operation for a patient of unstable angina with hypoxia is reported. A 80-year-old woman was admitted with severe chest oppression. The selective coronary angiogram revealed 3-vessel disease. Symptoms were uncontrolled by medical therapy. Aorto-coronary bypass surgery (with 3-saphenous vein grafts) was followed by excellent post-operative course. The patient has been asymptomatic for more than 1 year after operation.

Acute Disease↗
PubMed1989

Mandibular reconstruction with subsequent denture implantation.

A 23-year-old female patient with ameloblastoma on the right side of the mandible is presented. The affected mandible was excised and reconstructed with a free vascularised scapular bone graft followed by dental reconstruction with an artificial dental root. This is a preliminary report and the benefits of the procedure are discussed.

Adult↗
PubMed1989

Eye socket reconstruction with free radial forearm flap.

Deformity of the orbital region and contraction of the eye socket were encountered in 3 patients who in their infancy underwent exenteration of the orbit and postoperative irradiation for the treatment of retinoblastoma. These major problems were attributed to the less-vascularized cicatricial conjunctiva left in place. To solve these disadvantages, a microvascular technique using a free radial forearm flap was adopted. A large permanent eye socket was achieved and depression deformity of the orbital region was corrected in a one-stage operation. This is, to our knowledge, the first report on the use of a free vascularized skin flap for "malignant contracture" of an anophthalmic eye socket. The excellent cosmetic results of this method are demonstrated.

Adolescent↗
PubMed1988

Partial purification, characterization, and kinetic analysis of isoflavone 5-O-methyltransferase from yellow lupin roots.

An isoflavone 5-O-methyltransferase was partially purified from the roots of yellow lupin (Lupinus luteus) by fractional precipitation with ammonium sulfate, followed by gel filtration and ion-exchange chromatography using a fast-protein liquid chromatography system. This enzyme, which was purified 810-fold, catalyzed position-specific methylation of the 5-hydroxyl group of a number of substituted isoflavones. The methyltransferase had a pH optimum of 7 in phosphate buffer, an apparent pI of 5.2, a molecular weight of 55,000, no requirement for Mg2+, and was inhibited by various SH-group reagents. Substrate interaction kinetics of the isoflavonoid substrate and S-adenosyl-L-methionine gave converging lines which were consistent with a sequential bireactant binding mechanism. Furthermore, product inhibition studies showed competitive inhibition between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine and noncompetitive inhibition between the isoflavone and either S-adenosyl-L-homocysteine or the 5-O-methylisoflavone. The kinetic patterns obtained were consistent with an ordered bi bi mechanism, where S-adenosyl-L-methionine is the first substrate to bind to the enzyme and S-adenosyl-L-homocysteine is the final product released. The physiological role of this enzyme is discussed in relation to the biosynthesis of 5-O-methylisoflavones of this tissue.

Cations, Divalent↗
PubMed1987

Unilateral athelia with a subcutaneous dermoid cyst.

A case of unilateral athelia with a subcutaneous dermoid cyst in the area in question is reported. The histologic features of the cyst wall suggest that it is derived from a base in the nipple-areola complex. Dozens of cases of congenital absence of the breast have been reported, some of them associated with congenital anhidrotic ectodermal dysplasia, others with additional musculoskeletal abnormalities, and still others normal in other respects. But to our knowledge, the combination of athelia and corresponding subcutaneous dermoid cyst has not been reported.

Adolescent↗
PubMed1983

The coupling valve graft: a procedure for double-valve replacement.

Coupling valve grafting, a procedure to enlarge the annulus of the aortic valve and of the mitral valve simultaneously, is described. It consists of extending the J-shaped aortotomy through the middle of the noncoronary cusp into the superior aspect of the left atrium and down the anterior leaflet of the mitral valve. Then the mitral and aortic valves are replaced with a coupling valve graft, a vascular prosthesis attached to two prosthetic valves. This technique seems to be most suitable for patients in whom the valves of both annuli are narrow, as is often seen in aortic and mitral stenosis. Since both valve annuli can be enlarged greatly in this procedure, combinations of prosthetic valve sizes can be freely chosen for the two valves.

Adult↗