Henry Keller, MD, of New York and the Alyn Hospital in Jerusalem.
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Biomedical subjects
Publications and source records attributed to S T Winter.
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A second family with the autosomal recessive disorder now referred to as the limb/pelvis-hypoplasia/aplasia syndrome is reported. It is speculated that the gene for this rare skeletal dysplasia may be confined to the Middle East gene pool. The disorder has been shown to be diagnosable prenatally in a pregnancy at risk by using ultrasonography.
The prevalence of exercise-induced asthma was studied in 313 Haifa schoolchildren, 160 living in an unpolluted urban area close to the sea and 153 living in a rural kibbutz (communal agricultural settlement) in the proximity of polluting industries. The overall prevalence was 8.6%; it was higher in the kibbutz group, but the difference was not significant. The prevalence tended to fall with increasing age and did not change with sex.
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Ninety-seven healthy newborns with a Sydney line in 143 palms were re-examined between the ages of 10 and 14 months. The Sydney line was no longer present at follow-up in 58.8 per cent of these infants and in 66.4 per cent of the palms. It appears that the Sydney line, unlike the simian line and its variants, is age-dependent and is not a permanent structure of early intrauterine origin.
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This study comprises 260 children aged less than or equal to 13 yr hospitalized following accidents during a 9-mo period for a total of 923 hospital days. The ratio of boys to girls was 1.8:1. There were 21 road accidents and 104 accidents in the home; 75.4% of the accidents took place after school hours. Half of the admissions were for head trauma; 96 injuries were serious; and 78 patients required general anesthesia. In 67 families, there had been at least one previous childhood accident requiring hospitalization of the cohort child or sibling; factors in this group may have been the child's temperament or tension in the home.
Six demographic and health characteristics of newborn infants were used to develop an additive risk score for predicting first admissions to hospitals during their first two years of life. The scoring system, developed for a cohort of 5,243 infants in Haifa, identified an at-risk group comprising 23% of the population, in whom 43% of hospital admission events occurred. The same scores, applied to a cohort of 5,800 infants in Jerusalem, identified an at-risk group comprising 22% of the population and predicted 35% of hospital admission events. Possible reasons for the differences between the two cities are discussed.
Repeated acute abdominal episodes of Familial Mediterranean Fever can lead to peritoneal bands. These may cause mechanical obstruction of the bowel, requiring surgical intervention. Three such cases are reported, including one fatality.
The results of a single Denver Developmental Screening Test performed at the age of nine months on 823 infants attending maternal and child health centres were compared with the developmental information recorded by public health nurses during their routine well-baby care of these same infants. The single Denver test detected a significantly greater number of infants with developmental delay than did the routine observations, and the nurses tended to under-use the available resources for developmental assessment. Suggestions are made for more effective use of maternal and child health centres in the primary recognition of developmental delay.
A 20-item questionnaire on breast feeding was completed by 242 high school girls ranging in age from 15 to 18 years old. Many girls had significant apprehensions concerning breast feeding, including deleterious influences on the mother and ignorance of the benefits for the infant. Most stated that they would be interested in learning about breast feeding during school health lessons. Offering information to teenagers and correcting their apprehensions might help create sounder knowledge upon which mature motivation can be formulated.
The steady decline in the infant mortality rate among Jews showed a temporary, distressing reversal during the years immediately following the establishment of the State of Israel, but thereafter the rate again declined and the reduction was maintained. The rate fell to 13.9/1,000 live births in 1977. During recent years, there has been a significant parallel fall in the number of deaths during the first six days of life, reaching 8.0/1,000 live births in 1977. Hospital admissions, as an indicator of morbidity, now show less children with infantile diarrhea, formerly a major cause of hospitalization. Although Israel has reached reasonably satisfactory standards of infant health, there remains much room for improvement.
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A dermatoglyphic and palmar crease analysis was carried out in 100 children aged six months to five years with psychomotor retardation (excluding Down's syndrome). When compared with 121 of the parents and a random group of 168 school-children, certain unusual features were found to be twice as common in the retarded children, demonstrating that these features may indicate an 'at risk' infant if found during routine examination of the newborn.
The urinary calcium/creatinine ratio was estimated in two groups of schoolboys--village Arabs and urban Jewish (Ashkenazic) schoolboys, aged 10 to 11 years. Both the mean calcium/creatinine ratio and the frequency of hypercalciuria were higher among the Arab boys, and may be related to the higher incidence of chilidhood urolithiasis in Arab children in Israel.
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