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Biomedical subjects

S Svane

Publications and source records attributed to S Svane.

At least 19 recordsLinked to original sources
PubMed1997

Simultaneous Wilms' tumours in monozygotic twins. Case report and review of the literature.

Familial cases of Wilms' tumour indicate that some of these tumours have a genetic origin. However, the role of constitutional genetic and shared environmental factors in the causation of these tumours, is not well understood. We have observed the very rare occurrence of simultaneous Wilms' tumour in monozygotic twins; one of them with a bilateral tumour and fatal outcome at 18 months of age. The other was in good health at the age of 24 years.

Adolescent↗
PubMed1996

[Simultaneous pulmonary tuberculosis and bronchial cancer. A diagnostic pitfall].

Simultaneous development of unsuspected primary cancer in close vicinity to an active tuberculous process of the lung can seriously complicate diagnosis. In most reported cases, a long interval had elapsed before carcinoma was suspected. Such a case is described. Initially a 72-year-old man with carvernous tuberculosis was successfully treated with adequate antituberculous drugs. After 18 weeks of treatment, the patient's pulmonary parenchymal status showed no further improvement, and after 25 weeks the lung infiltration was seen to be slowly increasing. Thoracotomy performed after 40 weeks of treatment revealed inoperable squamous cell carcinoma and apparently healed tuberculosis.

Aged↗
PubMed1996

[Tuberculous lymphadenitis caused by Mycobacterium bovis].

According to the literature, bovine tuberculosis in man has been an illness of minor importance in Norway, unlike in Sweden and Denmark. This situation cannot be explained, since in former days infected cattle were a problem in the southeastern part of the country in particular. No case of bovine tuberculosis in humans has been reported in Norway since 1940. Recently we have observed a 29-year-old female immigrant from India with cervical lymph node tuberculosis caused by M. bovis. A second case is a 77-year-old Norwegian male. In the 1920s, at the age of ten, he was infected in Norway by drinking raw milk from tuberculous cattle. He developed tuberculosis of the mesenterial lymph nodes. Neither of these patients had tuberculosis in any other part of their body. Previous Norwegian reports, covering eight cases, are summarized.

Adult↗
PubMed1995

[Acute psychosis--an unusual clinical manifestation of primary hyperparathyroidism].

In 1942, the Norwegian psychiatrist Eitinger drew attention to the fact that acute psychosis may be the presenting and major symptom of primary hyperparathyroidism. A case of this variety is reported. In the course of two months a 77-year old woman developed an acute psychosis characterized by apathy, amnesia, somatic delusions and hallucinations. Initially, the case was misinterpreted as senile dementia. The serum calcium level was 4.3 mmol/l. After parathyroidectomy her mental symptoms were completely relieved.

Acute Disease↗
PubMed1995

Primary suture of anorectal abscess. A randomized study comparing treatment with clindamycin vs. clindamycin and Gentacoll.

UNLABELLED: Gentacoll (Schering-Plough A/S, DK-3520 Farum, Denmark) implant is a biologically absorbable collagen with gentamicin, which enables local use of gentamicin in an abscess cavity. PURPOSE: To increase healing rate in treatment of perianal abscess with primary suture, the effect of intraoperative parenteral clindamycin and Gentacoll was investigated against monotherapy with intraoperative clindamycin in a randomized study. METHODS: One hundred seven patients, 55 in the Gentacoll group and 52 in the control group, were enrolled in the study and followed for three months. RESULTS: Twelve patients (22 percent) in the Gentacoll group developed a new abscess and/or fistula. In the control group nine patients (17 percent) developed a recurrent abscess or a fistula. In both groups 43 patients had an uneventful course. The differences between the two groups were not significant. Of all 107 patients, 19.5 percent had recurrent disease in the follow-up period. Duration of hospitalization and reconvalescence were identical in both groups. One case of superficial thrombophlebitis was seen after clindamycin. No other adverse effects to either Gentacoll or clindamycin were seen. CONCLUSION: The study shows that Gentacoll is a safe preparation but is without value as a supplement to clindamycin in the treatment of acute perianal abscess with primary suture. The study has documented the value of this treatment under cover with a intraoperative dose of clindamycin.

Abscess↗
PubMed1992

[Aortic aneurysm misinterpreted as pulmonary tumor].

Two cases have been reported of patients with an atherosclerotic saccular aneurysm of the descending aorta which simulated a left-sided lung neoplasm. Despite advanced diagnostic procedures, the diagnosis was not made before thoracotomy. The authors discuss some of the diagnostic problems related to thoracic saccular aneurysms.

Aged↗
PubMed1992

[Acute pancreatitis after treatment with sulindac].

Two women, aged 91 and 46 years respectively, developed acute pancreatitis following treatment with sulindac (Clinoril) for five weeks in the one case and four and a half years in the other. The oldest patient became acutely ill. An emergency laparotomy was performed which showed considerable pancreatic edema and typical fat necroses. The other case presented a more protracted course and was not operated. Restitution was remarkably quick in both patients after cessation of the sulindac treatment.

Acute Disease↗
PubMed1992

[Hemangiomatosis of the small intestine with profuse bleeding].

Emergency laparotomy was performed in a 61-year-old man because of melena. The reason for the bleeding was intestinal hemangiomatosis with multiple, small, dark tumours in two segments of the small intestine. The patient restituted completely after resection of the two affected intestinal segments. Microscopy showed submucosal cavernous hemangiomas. A review of the literature revealed that this condition is rare. Five previous Norwegian reports (1917-1964) are summarized in order to illustrate the substantial variations with regard to location, clinical course and pathological anatomical changes.

Emergencies↗
PubMed1992

Subcutaneous avulsion of the breast caused by a seat belt injury. Report on a case requiring emergency mastectomy.

A 60-year-old female car driver wearing a combined three-point lap-shoulder seat belt was involved in a head-on-collision. The entire right breast was separated from the chest wall, whereas the overlying skin remained intact. The injury resulted in a rapid development of a monstrous haematoma in the retromammary space, and required emergency mastectomy. Seat belt lesions of the female breast are seldom referred in the literature.

Accidents, Traffic↗
PubMed1991

[Pulmonary pseudotumor caused by Cryptococcus neoformans].

Since 1923, eight cases of cryptococcosis have been described in Norway, all with meningeal affection. A distinct, solitary infiltration in the upper lobe of the right lung was discovered in a 68 year-old woman. The lobe was extirpated. Microbiological and histological investigations showed infection with Cryptococcus neoformans. No antimycotic treatment was given. Four months later the patient developed osteomyelitis of the skull due to cryptococcosis, and was treated successfully with amphotericin B and flucytosin. Further investigation of the patient revealed a defect in the T-lymphocyte immune system, but it is uncertain whether this was of any significance for the development of the cryptococcus infection.

Aged↗
PubMed1991

[Pulmonary plasma cell granuloma. Inflammatory pseudotumor in the lung].

A 62-year-old woman developed minor symptoms of subacute respiratory infection simulating bronchitis. Six weeks later, X-ray of the chest revealed a solitary round infiltration ("coin lesion") in the basal part of the left lung. No diagnosis could be made preoperatively. Thoracotomy demonstrated a plasma cell granuloma. The affected pulmonary segment of the basal part of the upper lobe was resected. There were no clinical nor radiological signs of recurrence five years after the operation.

Female↗
PubMed1991

[Ectopic liver in the gallbladder and cholestasis].

A small ectopic liver on serosa of the gallbladder was demonstrated peroperatively in two patients with extrahepatic cholestasis and considerable distention of the biliary system. The histological architecture of the small liver was similar to that of a normal liver, with a minute bile duct communicating with the lumen of the gallbladder. This explains why the cholestasis provoked identical pathological changes in both liver and the ectopic liver tissue.

Adult↗
PubMed1990

[Vena cava superior syndrome in total parenteral nutrition. Vena cava superior thrombosis caused by a central venous catheter].

Two patients developed superior vena cava syndrome following total parenteral nutrition through a central venous catheter. Infection may have contributed to the development of the superior vena cava thromboses. In one patient a "sleeve thrombus" probably caused multiple pulmonary embolisms after the catheter was withdrawn. The other patient had a mural thrombosis with complete occlusion of the superior vena cava. The author emphasizes the importance of early diagnosis and correct treatment in order to reduce the high mortality rate due to this serious complication to central venous catheters.

Catheterization, Central Venous↗
PubMed1990

Treatment of ureteric colic. Intravenous versus rectal administration of indomethacin.

A randomised multicentre clinical trial was undertaken to compare the effect on pain of indomethacin administered either intravenously or rectally to 116 patients with ureteric colic. Adverse reactions were also assessed. Of the patients receiving the intravenous injection, 48/53 (91%) achieved good pain relief (i.e. no supplementary analgesia was required) 30 min after administration, compared with 46/63 (73%) receiving the enema. Significantly more side effects occurred in the group treated intravenously. It was concluded that indomethacin administered as an enema was less effective than the intravenous form, but it should be regarded as a good alternative in the treatment of ureteric colic.

Administration, Rectal↗
PubMed1988

Cefoxitin for one day vs. ampicillin and metronidazole for three days in elective colorectal surgery. A prospective, randomized, multicenter study.

In a multicenter study the prophylactic efficacy of two antibiotic regimens was tested against postoperative septic complications following elective colorectal surgery. The study was conducted in a prospective block-randomized design. Patients were preoperatively allocated to either ampicillin, 1 gm, four times daily, and metronidazole, 0.5 gm, three times daily, for 72 hours, or to cefoxitin, 2 gm, given three times in a period of 10 hours. Both regimens were initiated immediately before surgery. Forty-five patients were withdrawn from the study after randomization. Three hundred fifty two patients (175 receiving ampicillin and metronidazole and 177 receiving cefoxitin) completed the study and were followed for one month postoperatively. The frequency of septic and nonseptic complications was not statistically significant different between the two regimens. About one third of all septic complications appeared more than two weeks after surgery. It is concluded that short-term treatment with cefoxitin is at least as efficient as a three-day treatment with ampicillin and metronidazole.

Aged↗
PubMed1988

Turner's syndrome associated with chronic inflammatory bowel disease. A case report and review of the literature.

A 26-year-old woman with Turner's syndrome (45,X/46,X,i(Xq] and Crohn's disease is reported. The inflammatory bowel disease was aggressive with development of intestinal fistulas. Total proctocolectomy was performed, and the patient recovered remarkably well post-operatively. The association of Turner's syndrome and inflammatory bowel disease is reviewed, with special reference to karyotype, severity, mortality and treatment.

Adolescent↗