Unusual cases of herpes zoster involving cranial nerves.
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Biomedical subjects
Publications and source records attributed to S Sundar.
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Twenty five patients of essential hypertension were studied. Of these, 20 patients were not given any antihypertensive drug treatment (Group A); other 5 had to be put on antihypertensive drugs before including them in the study (Group B). These patients were demonstrated "Shavasana" and trained to perform it correctly. Shavasana therapy was continued for six months. There was a statistically significant fall in both mean systolic and diastolic pressure of both groups. Further, there was a significant reduction in doses of antihypertensive drugs, being given to patients of group B. In 65% patients of group A, blood pressure could be controlled with Shavasana only and no drug was needed in them at all. Blood pressure rose significantly to pre-Shavasana levels in patients who left practising yoga. Thus, with use of yoga (Shavasana) in therapy of hypertension, requirement of antihypertensive drugs may be significantly decreased and in some cases may be totally dispensed with and it may be an useful adjunct in treatment of hypertension.
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Serum levels of sodium, potassium, calcium, magnesium and digoxin were studied in 67 patients on maintenance dose of digoxin, 42 with digitoxicity and 25 without. The mean serum digoxin level of toxic group was significantly higher (p less than 0.001) than non-toxic group. The mean serum potassium was significantly lower in toxic group (p less than 0.05) as compared to the non-toxic group. Of the toxic patients, 23.8% had hypokalemia. Hypokalemia resulted by significantly higher (p less than 0.005) dose of diuretic used in toxic group. The mean serum digoxin level of hypokalemic toxic group was significantly lower as compared to the normokalemic toxic group (p less than 0.001) and it was interesting to note that all hypokalemic toxic patients had their serum digoxin levels below 3 ng/ml (3.84 n mol/ml) and well within therapeutic range. There was a positive correlation between serum digoxin and potassium level amongst toxic patients (p less than 0.001). Thus, in patients on maintenance dose of digoxin therapy, use of large dosage of diuretics may result in hypokalemia, causing digitalis toxicity even at low serum digoxin levels. Serum digoxin level alone may fail as an independent guide in diagnosis of digoxin toxicity in presence of hypokalemia.
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The study was done to determine IgG and IgM antitetanus antibodies in mothers after antenatal immunization, and extent of transfer to the baby as measured by cord levels of tetanus specific IgG and IgM by ELISA using enzyme penicillinase and to study the effect of nutritional status of mothers on antibody response to tetanus toxoid and corresponding cord levels also to determine the number of doses required for protective antibody levels in cord blood. The results obtained in sera of 100 mothers at the time of delivery and their respective cord sera and results of 43 different control sera are discussed using ELISA technique.