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Biomedical subjects

S Sudhindran

Publications and source records attributed to S Sudhindran.

30 records · Page 2Linked to original sources
PubMed1997

Perioperative blood transfusion: a plea for guidelines.

Red blood cells are still transfused inappropriately in spite of recent media attention and public awareness about the risks of blood products. A prospective audit was conducted to determine the avoidable blood transfusion rates in the elective perioperative setting utilising the guidelines issued by the American College of Physicians (ACP). Of 82 consecutive adult patients who were admitted for major elective surgery over a 3-month period, 28 were transfused a total of 94 units of homologous SAG-M blood, of which 50 (53%) were inappropriate as recommended by the ACP guidelines. Violations of the guidelines were perioperative transfusion in bleeding patients who were haemodynamically stable (31%) and transfusion in asymptomatic, stable patients solely to attain a haemoglobin level above 10 g% (22%). There is a need for objective, easily adaptable and widely disseminated consensus guidelines to the indications for red blood cell transfusion.

Adult↗
PubMed1994

Pseudomyxoma peritonei: a report of eight cases.

OBJECTIVE: To assess the effectiveness of surgical treatment for pseudomyxoma peritonei. DESIGN: Retrospective analysis. SETTING: Referral center. PATIENTS: Eight patients with pseudomyxoma peritonei, five with mucinous tumors of the ovary and three with mucoceles of the appendix. INTERVENTION: All patients underwent cytoreductive surgery with removal of source i.e. panhysterectomy with appendicectomy in 5 and appendicectomy in 3. Systemic chemotherapy was used in 6 and systemic plus intraperitoneal chemotherapy in one case. RESULTS: Over 18 to 86 months' follow up, two patients died (at 18 and 24 mo) and 2 are alive with recurrence. Recurrence occurred only in those with inadequate clearance of mucinous material at the initial operation. The remaining 4 patients are free of disease. CONCLUSION: Aggressive surgical therapy with-chemotherapy is effective in providing long-term relief or cure in pseudomyxoma peritonei.

Adult↗
PubMedDate not supplied

Incidental detection of tubular esophageal duplication in gastric cardia malignancy.

Congenital esophageal duplications represent about 15% of digestive tract duplications. We report a 38-year-old man who presented with longstanding heartburn and recent dysphagia. Endoscopy showed communicating tubular duplication of lower esophagus with ulceroproliferative growth at the gastric cardia extending into the lower esophagus. Histology of radical esophagogastrectomy specimen showed poorly differentiated adenocarcinoma of gastric cardia without evidence of Barrett's esophagus.

Adenocarcinoma↗