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Biomedical subjects

S Stoyanov

Publications and source records attributed to S Stoyanov.

12 recordsLinked to original sources
PubMed2006

Shell-driven magnetic stability in core-shell nanoparticles.

The magnetic properties of ferromagnetic-antiferromagnetic Co-CoO core-shell nanoparticles are investigated as a function of the in-plane coverage density from 3.5% to 15%. The superparamagnetic blocking temperature, the coercivity, and the bias field radically increase with increasing coverage. This behavior cannot be attributed to the overall interactions between cores. Rather, it can be semiquantitatively understood by assuming that the shells of isolated core-shell nanoparticles have strongly degraded magnetic properties, which are rapidly recovered as nanoparticles come into contact.

Cobalt↗
PubMed2003

Application of spectroscopic and computational methods in the study of the electronic excitations of partially silylated hydroxyquinones.

The silylation of hydroxynaphthoquinones and hydroxyanthraquinones with N-methyl-N-(tert-butyldimethylsilyl)-2,2,2-trifluoroacetamide, in one step reaction, under mild conditions, has led, in nearly quantitative yields, to the isolation of hydrolytically stable partially silylated products (only of the hydroxyl groups), which differ dramatically in color from the starting materials. The spectroscopic investigation of the silylated products in solution as well as the correlation of the observed data with computationally derived results have been carried out within a study aiming at the understanding of the visible maxima shift to either the ultraviolet or near-infrared region of the electromagnetic spectrum, which would imply availability of the silylated products in a variety of related applications.

Computational Biology↗
PubMed1995

Characterization of human, mouse and rabbit anti-gliadin antibodies by ELISA and western blotting.

Monoclonal, hyperimmune rabbit and human serum anti-gliadin antibodies were analyzed by ELISA and immunoblotting techniques. In Western blotting the difference in reactivity between monoclonal and human antibodies was quantitative rather than qualitative. Rabbit antisera differed in reactivity according to the protein used for immunization. The rabbits immunized by the peptic-tryptic pancreatic digest of gliadin reacted similarly to the patients. In ELISA, significantly higher reactivity with crude, A-, glyc-gli, alpha-, beta- and omega-gliadins was found in the patients' sera than in controls.

Animals↗
PubMed1988

Monoclonal antibodies reacting with gliadin as tools for assessing antigenic structure responsible for exacerbation of celiac disease.

Monoclonal antibodies reactive with gliadin were prepared by fusion of spleen cells isolated from gliadin-immunized BALB/c mice with myeloma cells. The reactivity of mAbs with different preparations of gliadin and their enzymatic digest were measured using ELISA method. The mAb produced by GL 1 clone was shown to react preferentially with alpha-gliadin and its enzymatic digest.

Antibodies, Monoclonal↗
PubMed1988

Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74).

The specificities of several monoclonal antibodies described by us earlier were determined more exactly: (1) antibodies MEM-31 and MEM-32 are directed against CD8 and CD5 T cell antigens, respectively: (2) MEM-15 and MEM-18 react with the CD14 monocyte antigen; (3) MEM-28 recognizes the CD45 pan-leucocyte antigen. Several new monoclonal antibodies are described: (4) MEM-55 and MEM-58, reactive with subsets of CD45-related molecules; (5) MEM-43, recognizing a broadly expressed 18-kDa glycoprotein; (6) MEM-57, reacting with the CD3 antigen complex: (7) MEM-59 recognizing the CD43 leucocyte antigen; (8) MEM-74, which reacts with an unidentified antigen strongly expressed on several cell lines and many leukaemic cells but absent from most resting leucocytes; (9) MEM-75, directed against transferrin receptor, and (10) MEM-78, recognizing CD10 (CALLA) antigen.

Antibodies, Monoclonal↗
PubMed1978

A simple alarm device for the Bennet PR-2 ventilator.

A simple alarm device for use with the Bennet PR-2 ventilator is described. It is based on the operation of a photo-electric cell, is simple in construction, and can be used on other types of ventilators if the pressure gauge is compatible.

Humans↗
PubMed1977

Cutting fluids and their effects on the skin of mice. An experimental study with special reference to carcinogenicity.

Reports of skin malignancies due to occupational exposure have decreased since the introduction of solvent-refining of mineral oil fraction in the manufacture of oil based cutting fluids. Commercial mineral oil based cutting fluids caused local and general pathological changes after repeated application to the skin of mice in the present study. Forty-eight per cent of the mice exposed to oils showed severe dysplasia or malignancy of the skin on histological examination. The corresponding figure for the control group, where various additives were used was 8 per cent. The frequency of papillomas was also increased in the mice exposed to oils. The systemic lesions included focal necrosis of the liver, associated with amyloid deposition, as well as amyloidosis of the skin, spleen and kidneys. The substances responsible for these apparent carcinogenic properties of the complex mixtures may be polycyclic hydrocarbons; the latter are still present in the commercial products despite solvent refining; on the other hand the carcinogens may be additives to the cutting oils the composition of which is generally a trade secret.

Amyloidosis↗