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Biomedical subjects

S Stefanini

Publications and source records attributed to S Stefanini.

60 records · Page 4Linked to original sources
PubMedDate not supplied

[Acute severe pancreatitis caused by anti-HIV drugs].

Acute pancreatitis in patients with HIV infection is infrequent and often not recognized. Autopsies performed on patients died for different pathologies show pancreatic lesions approximately in 50% of cases. The etiological factors associated with acute pancreatitis are related to HIV infection and particularly to drugs used to treat the syndrome or to prevent opportunistic infections. We report a case in a 38 years old male patient with AIDS without risk factors for acute pancreatitis in which the disease developed while taking Stavudine, Lamivudine and Indinavir. His conditions improved with intensive medical therapy. The subsequent medical course became complicated. The patient died after 75 days for severe abdominal haemorrhage. A review of the literature reports several cases of A.P. in HIV patients mainly related to opportunistic infections. Many authors regard the medical treatment of HIV syndrome as etiological factor but a casual relationship was never demonstrated. The aim of the present paper is to underline that besides Lamivudine also Stavudine and Indinavir might be related to acute pancreatitis. Clinical and laboratory investigations in HIV patients are therefore indicated for an earlier diagnosis and treatment.

Acute Disease↗
PubMedDate not supplied

[Gastrointestinal stromal tumors: our experience].

The authors report their experience on the treatment of GIST. They point out the importance of classification of the disease in low, medium and high risk neoplasms based on the characteristic of the tumour: site, volume and mytotic index as the Consensus Conference of Bethesda recently established. Surgical procedure remains the most important treatment in localized disease, while patients with advanced disease can benefit from imatinib, a chemotherapeutic agent recently introduced, as an adjuvant therapy.

Aged↗
PubMedDate not supplied

[3-dimensional automatic dosimetry in curietherapy].

Isodose curves can be viewed on multiple planes along with the radioactive implant and anatomical structures by projecting them on a video-display. The main options offered are the parallel projection of the implant selecting all the possible rotations, zooming and shifting, calculation of distance between two points of a selected plane, stereoscopic display.

Brachytherapy↗