Search PubMed⌕ Search

Biomedical subjects

S Spasov

Publications and source records attributed to S Spasov.

At least 55 records · Page 3Linked to original sources

[The functional state of the adrenal cortex in patients with gonadal dysgenesis and a female phenotype].

Excretion of 17-KS and 17-OCS was studied in the urine of 86 patients with various cytogenetic variants of gonad dysgenesis of a female phenotype under basic conditions and after ACTH stimulation; in 10 patients endogenous hypophyseal ACTH reserve after block of the adrenal cortex by metopyrone was investigated as well. A conclusion was drawn on the presence in these patients of differnet types of deviations of the adrenal gland function. In some of the cases there is a primary "global" or dissociated injury of the adrenal cortex, apparently directly associated with gonosome anomaly; in other cases--with disturbed regulation of ACTH secretion.

17-Hydroxycorticosteroids↗