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Biomedical subjects

S Soto

Publications and source records attributed to S Soto.

43 records · Page 3Linked to original sources
PubMedDate not supplied

[Cardiorespiratory failure: results of resuscitation in a pediatric ICU].

Along one year, cardiorespiratory resuscitation was done to 71 patients, aged 3 days to 10 years (median 3.5 month), in a pediatric intensive care unit. Although 39 patients (55%) recovered through first-stage treatment, in 17 the arrest was recurrent and they died in the following 24 hours. Only 12 (16.9%) children definitely survived. No patients requiring reanimation for more than 10 min, survived. Asystole was the most frequent arrhythmia (92%). There were only 4 cases of ventricular fibrillation, all occurred in patients with congenital heart disease, and no one recovered. Survivors have not evidence of neurological deficiencies, and only one died along one year follow up, because of congenital heart disease.

Child↗
PubMedDate not supplied

RT-PCR comparative study of viral load levels in the HIV positive population in Puerto Rico before and after protease inhibitor regimen implanted.

Ponce School of Medicine AIDS Research Program conducted a large scale viral load assessment of Puerto Ricans who are infected by human immunodeficiency virus type 1 (HIV-1) during the summer of 1996 through the Roche ACCESS program before general implementation of combination therapy. Since January 1997, it has monitored those HIV-1 patients who are under treatments at most HIV-1 health care clinics, including both public and private. The present study was conducted to evaluate how the new treatment has generally impacted on the HIV-1 disease status of HIV-1 infected population in the eight Immunology Clinics. Assessment was made by consecutively monitoring the changes in HIV-1 viral load profiles of the population from January to September, 1997. A large majority of samples were delivered for viral load assessment without information of their treatment status, and only a small number of samples were identifiable either as baseline or followup. Despite the paucity of individual information, remarkable improvements of HIV-1 (+) population at large were evident. For example, in the summer of 1996 (ACCESS), population median viral load was 51,842; only 9% of the population had viral load less than 500 viral RNA copies/ml plasma and 72% had over 10,000 copies/ml. By July-September, 1997, the population median dropped to 8,679 (83%); 23% were below 500 copies/ml (+156%) and the proportion of patients who had over 10,000 copies/ml was reduced to 48% (-33%). The group of individuals who were positively identified as "follow-up" (i.e., under active treatment) had a median of 37128 copies/ml (-94%); 28% were below 500 copies/ml (+211%) and only 40% had more than 10,000 copies/ml (-44%). It is obvious that the implementation of triple combination therapy by PASET in 1997, has very markedly improve the HIV-1 disease status of HIV-1 (+) population in Puerto Rico.

HIV Infections↗