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Biomedical subjects

S Sikimić

Publications and source records attributed to S Sikimić.

17 recordsLinked to original sources

[Late detection of bronchogenic carcinoma].

The retrospective analysis of 1781 patients with bronchogenous carcinoma treated at the Institute of Pulmonary Diseases of the Military Medical Academy within the period 1971-1980 is presented. In 86% cases the disease was discovered according to symptoms because of which the patients had consulted physicians. The time between the onset and the detection of the disease was more than 3 months in the majority of patients and more than 6 months in one third of the patients. In the largest number of patients the disease was detected late when chances for successful intervention were diminished. Only in one third of the patients the disease was localized. Aiming to early detection of bronchogenous carcinoma it is essential to have good knowledge of symptoms both by patients and primary care physicians.

Adult↗

[Staphylococcal pneumonia associated with pneumatoceles, bilateral pyopneumothorax and sepsis].

A case of soldier with community acquired staphylococcal pneumonia and multiple pneumatoceles as the rare complication in adults is presented. Their recognition provides appropriate treatment. In the patient were developed bilateral pneumothorax, pleural empyema and sepsis. Surgical treatment was performed by thoracic drainage. Recovery of pulmonary function was poor, as distinguished from children.

Adolescent↗

[Personal experience in the diagnosis and treatment of pulmonary embolism].

The 188 patients with pulmonary embolism were treated at the Clinic for Pulmonary Diseases of the M.M.A. in the period 1979-1989. Clinical symptoms and signs, diagnostic procedures and therapy of pulmonary embolism are analysed. The diagnosis is difficult and is suggested by the predisposing factors, symptoms and signs of the disease as well as indirect diagnostic procedures. The contribution of perfusion lung scintigraphy is precious. Deep venous thrombosis of the lower extremities, the source of pulmonary embolism, is commonly clinically absent. The complete cure without complications was achieved in 156 (83%) patients. The most common complications were: early and late recurrences, hematuria and peptic bleeding. The lethal outcome occurred in two cases of basic disseminated malignant disease.

Adult↗

[Personal experience in the treatment of tuberculosis in patients in war areas].

In the four-year period (1991-1995), 96 tuberculosis patients from the war areas of former Yugoslavia were treated in the Clinic for Lung Diseases of Military Medical Academy, that makes 31% of total number of sick and treated for tuberculosis-309 (100%). In group I (patients from war areas) there were 45 cases of cavernous pulmonary tuberculosis (47%), 28 bilateral (29%), 16 pleurisy (16.7%) and 6 cases of extensive pulmonary tuberculosis (5.1%). Among 213 patients (100%) from group II (patients from FR Yugoslavia), 81 patients had cavernous pulmonary tuberculosis (38%), 49 patients had bilateral (23%), 33 patients had pleurisy (15.5%) and 6 patients had extensive pulmonary tuberculosis (2.8%). In group I the diagnosis was bacteriologically and/or histopathologically proved in 94.8% cases: by finding of acid-resistant bacilli in sputum and other biological materials in 69 patients (72%), by positive Löwenstein's cultures in 73 patients (76%) and by histopathological result of tuberculosis inflammation in 34 patients (35.4%). In group II tuberculosis was bacteriologically and/or histopathologically proved in 134 patients (63%) by acid-resistant bacilli in sputum and other biological materials, in 141 patient (66%) by positive Löwenstein's culture and in 71 patient by positive histopathological results. Pulmonary tuberculosis in war areas is characterized by greater frequency of severe clinical forms (cavernous, bilateral and extensive) and by high direct bacillarity.

Adult↗

[Endobronchial metastases in extrapulmonary malignant tumors].

Endobronchial metastases of extrapulmonary malignant tumors are very rare and they appear in 1-2% of all the pulmonary metastases cases. By their endoscopic presentation, they are similar to primary bronchogenic carcinoma. Eleven patients with endobronchial metastases were presented, 8 male and 3 female. The average age was 58.27 years (from 37 to 72 years). Primary renal carcinoma existed in 2 patients. The one was operated 5 years before the metastases appeared in bronchus, and the metastases in bronchial wall contributed to the discovery of primary tumor in the other patient. Endobronchial metastases appeared in 3 patients, 2 years after the surgery of malignant colonic or rectal tumor, and in fourth patient it appeared 5 years after the surgery. One female patient sustained mastectomy and the radiation therapy was performed 11 years before the bronchial metastases occurred and the other female patient had the disease revealed a year ago and the polytherapy was performed. In the female patient with non Hodgkin Lymphoma, the change in bronchus was revealed simultaneously as the primary disease. Endobronchial metastases appeared in 2 patients two years after the surgery of malignant melanoma. The disease diagnosis was set by clinical-radiological examination, by endoscopy and by the comparison of histopathologic finding of primary carcinoma and metastases.

Adult↗

[Recurrent abscessing pneumonia caused by Nocardia].

In female patient, 19 years old, disease occurred when she was 5. Thoracotomy with atypical resection of lung part was performed for the abscess in right lobe. Nocardia was bacteriologically confirmed. In the next 3 years, she was treated for pneumonia several times. When she was 19, abscess-forming pneumonia that recurrently occurred after the antibiotic therapy cease was established in right lobe. Nocardia was isolated by bronchoscopically taken aspirate, bacteriologically stained by Gramm, Ziehl-Neelsen and Kinyon and cultivated on several bacteriological and mycological media. She has been treated by antibiotic combination (sulfamethoxazole + trimethoprim and amoxicillin + clavulanic acid and minocycline) for 10 months. Subjective discomforts disappeared after the therapy, biohumoral findings were normal, and smaller pleuropulmonary adhesions on the right side could have been radiologically observed.

Adult↗