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Biomedical subjects

S Shuangshoti

Publications and source records attributed to S Shuangshoti.

At least 109 records · Page 6Linked to original sources
PubMed1982

Congenital osteolipoma of the skull.

A unique case of congenital osteolipoma of the skull occurred. A 27-year-old woman had multiple hard tumors affecting the frontal and parietal bones, the rim of the orbit, the maxilla, the base of the skull, and the horizontal part of the mandible on the right side. The slowly growing tumor was first noticed in the right parietal bone when she was born. The partially excised right frontoparietal lesion was composed of deformed and sclerotic trabeculae of bone and mature adipose tissue that formed an osteolipoma, which was regarded as hamartomatous. Its pathogenesis was suggested as associated with maldifferentiation of the mesenchyme or its derivatives toward the osseous and adipose tissue at the early development of the cranium.

Adult↗
PubMed1981

Heterotopias of brain as a cause of infantile regurgitation.

A girl had persistent regurgitation of food from the first week of life until death at 19 weeks of age. Postmortem examination revealed widespread congenital anomalies including neuronal and neuroglial heterotopias of the thalamus and centrum semiovale on the left side, subependymal regions of both lateral and third ventricles, and both rostral medullary pyramids; and hypoplasia of the thalamus and cerebrum of the left side, and both lenticular nuclei. Moreover, the left lateral ventricle was moderately dilated, secondary to partial occlusion of the ipsilateral interventricular foramen. The left thalamus and hemicerebrum, as well as both lenticular nuclei, were remarkable small. The brainstem was normal except for pyramidal neuronal and neuroglial heterotopias, a finding not previously reported. The mechanism producing a small left thalamus, lenticular nuclei, and cerebrum on the left side is suggested as a combination of hypoplasia from aberrant migration of neuroepithelial derivations, a dilated left lateral ventricle, and degeneration of connecting nerve fibers. Decrease in size of the right lenticular nucleus is the result of hypoplasia alone. It is proposed that the lesions in the thalamus and cerebrum on the left side were responsible for regurgitation because of imbalanced supranuclear control of intact nuclei in the brainstem.

Brain↗
PubMed1980

Parapharyngeal neoplasm of mixed mesenchymal and neuroepithelial origin.

A 20-year-old man had a left parapharyngeal neoplasm that displayed features of sarcoma of the nerve sheath, meningioma with an osseous component, rhabdomyosarcoma, and ganglioneuroma. The diverse cellular population suggests a tumor origin from the ectomesenchymal remnants of the neural crest. The mesenchymal part of the crest would differentiate into a variety of mesenchymal neoplastic elements, and the neuroectodermal (neuroepithelial) portion into the ganglioneuroma. These various neoplastic constituents then would form a neoplasm of mixed mesenchymal and neuroepithelial origin, or an ectomesenchymoma.

Adult↗
PubMed1980

Melanotic mucin-producing neuroepithelial neoplasm of mesencephalon with consideration of similar tumours in different locations.

A six month old boy had a mesencephalic melanotic neoplasm of the neuro-epithelial derivatives which produced mucin. Location in the mesencephalon and production of the mucin have not been described previously for this kind of intracranial tumour. The various cellular elements within the growth are in accord with diverse differentiations of the neuroepithelium of the neural tube, the neuroectodermal part of the neural crest, or both. Derivatives of the neural tube and crest can be melanotic, and some neuroepithelial derivatives (ependyma, oligodendrocyte, and choroidal epithelium) produce mucin. Hence, melanotic neuroepithelial neoplasms with mucinous product can occur. The present tumour is similar to lesions variously designated as melanotic medulloblastoma, retinal anlage tumour, and progonoma. Diverse differentiation of the neuroepithelium of the neural tube, or of the neuroectodermal part of the neural crest, or both would create these variously named tumours. The frequency of melanotic neuroepithelial neoplasms in infancy, and the presence of papillae strongly suggest congental derivation.

Adult↗