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Biomedical subjects

S Shishido

Publications and source records attributed to S Shishido.

At least 109 records · Page 6Linked to original sources

Different behaviour of inorganic and organic mercury in renal excretion with reference to effects of D-penicillamine.

Inorganic and organic mercury was measured in the red cells, plasma, and urine of five laboratory workers to examine the effect of D-penicillamine. The workers had had no particular exposure to mercurials. Before and during administration of D-penicillamine, inorganic mercury levels in plasma were significantly correlated with those in urine or 24-hour urinary outputs, but no significant correlation was found for organic mercury. Administration of D-penicillamine enhanced 24-hour urinary output to a much greater extent in organic than inorganic mercury. All the organic mercury levels in blood, red cells, and plasma were increased by D-penicillamine. This contrasted with the decrease of inorganic mercury levels in plasma.

Adult↗

Mercury in cigarettes.

Mercury in cigarettes of domestic and foreign products was measured by Magon's method, and the sample of a domestic brand was burned by a smoking machine and the smoke was collected for the measurement of mercury. In tobacco leaf and paper, only inorganic mercury was found in both domestic and foreign products. Its amount in tobacco leaf and paper of a piece of cigarette was about 60 ng in domestic products and about 30 ng in foreign products. By burning, the unit length of a cigarette released about 5-7 ng of mercury into smoke.

Filtration↗

Desquamation of renal epithelial cells as a route of mercury excretion in man: a preliminary study.

Urine of mercury-exposed workers in a chlorine manufacturing factory and of staffs of our laboratory was separated in the supernatant solution and the precipitate by a centrifugation of 105,000 Xg for 60 min. The ratio of the amount of inorganic mercury in the precipitate to that in the supernatant solution ranged from 0.23 to 4.84, and was dependent upon the level of urinary mercury. The role of the desquamation of tubular cells is suggested as a possible route of urinary excretion of mercury.

Adult↗

Micro-determination of bromine in biological samples using proton-induced x-ray emission spectroscopy.

The plasma level of bromine was measured by a proton-induced X-ray emission spectroscopy. Since bromine is the most difficult halogen to be determined and appears only in trace quantities, powerful techniques are required. The excellent reproducibility was obtained on 19 measurements on a sample of a single individual; the coefficient of variation was 6.3%. The average and standard deviation of plasma bromine levels on 47 young women were 0.50 and 0.10 mg/100 ml, respectively. Results by other methods in the literature were briefly reviewed.

Animals↗