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Biomedical subjects

S Shariff

Publications and source records attributed to S Shariff.

29 records · Page 2Linked to original sources

Primary pleural mesotheliomas in south India: a 25-year study.

In this report from South India, 15 patients with primary pleural mesothelioma have been diagnosed in the 25-year period 1, April 1966 through 31, March 1991, representing 0.02% of 76,239 biopsies received. The patients were mainly male with a mean age of 46.5 years. All except two had lived in urban Bangalore. None had been exposed to asbestos. The presentation clinically was peculiar, being continuous pricking pain, breathlessness, and cough with sputum. Physical and roentgenogram examination showed massive pleural effusion with irregular pleural thickening. Thoracotomy findings showed a distinct sessile nodularity with many slit-like spaces. Histologically, 14 were epithelial type mesotheliomas and 1 was a sarcomatous type. While the epithelial type neoplasms showed patchy squamoid differentiation, all showed mucin production. The CEA was always observed in areas of moderate differentiation. Spread occurred centrifugally to local structures on the same side as the lesion.

Adult↗

Mixed mesodermal tumours of the ureter.

This report is of a 78 year-old male with a mixed mesodermal tumour of the left ureter. A comparison of all reported patients with such neoplasms has been made in the discussion, in an attempt at characterization of this neoplasm.

Aged↗

Cutaneous eruptions in Indian tick typhus.

Although frequently unrecognized, rickettsial infections may be an important cause for fever and exanthem in persons presenting to physicians in South India. Most often these patients are referred to dermatology departments with a diagnosis of "drug eruption." In the current study the authors analyzed 12 cases of rickettsial fever that were seen in the dermatology department of St. John's Medical College Hospital, Bangalore, between 1985 and 1989. The distinctive cutaneous eruption was found to be an important clue to an early clinical diagnosis. Specific serodiagnosis enabled us to confirm that Indian tick typhus, a member of the spotted fever group, was the most frequent cause for rickettsial fever presenting at our hospital.

Adolescent↗

Herpetic cervicitis--a histo-morphologic study.

The purpose of this paper has been to find out the prevalence of herpetic cervicitis among routine surgical cervical biopsies, categorize the morphological changes and study their evolution. In a 51-month-period, 879 human uterine cervices were examined histologically, 19 percent (168) conforming to predetermined criteria for herpetic cervicitis. These criteria were typed as A through D starting with nuclear homogenization and passing through vesicle formation, bulla formation and finally ulceration. The type D lesion showed an agglomeration of Type A-C morphological changes occurring together, in addition to which focal submucosal haemorrhages were seen with severe congestion. The presence of the Herpes virus was confirmed with the Peroxidase-Antiperoxidase stain and the evolution of the bullae studied by means of the Alcian Blue-Periodic Acid Schiff stain (AB-PAS), Methyl Green-Pyronine (MG-P) stain and the Reticulum stain.

Cervix Uteri↗

Primary pulmonary rhabdomyosarcoma in a child, with a review of literature.

A cyst in the left lower lobe of the lung was removed from a 15-month-old girl and showed evidence suggesting a preexistent congenital cystic adenomatoid malformation; in addition a rhabdomyosarcoma was identified. Primitive mesenchyme and mesenchymal elements also were seen. The origin of the rhabdomyosarcoma is discussed. The findings in the present case are compared with those of all childhood pulmonary rhabdomyosarcomas reported in the literature. This report of a child with a coexistent congenital adenomatoid malformation and a rhabdomyosarcoma is the third of its kind in the literature.

Female↗

Aspiration cytology of echinococcus oligarthrus. A case report.

BACKGROUND: Fine needle aspiration cytology is a useful technique in the diagnosis of several parasitic infections. The present case highlights the aspiration cytology findings in a case of Echinococcus oligarthrus infection, a rare variant of the Echinococcus species affecting humans. To the best of our knowledge, this is the first case report on the cytology of E oligarthrus in English. CASE: A submandibular swelling developed in a 14-year-old male. A mistaken diagnosis of Cysticercus cellulosae was made on the first aspirate and of a hydatid cyst (Echinococcus granulosus) on the second aspirate. A diagnosis of E oligarthrus was made on subsequent histopathologic examination of the excised lesion. CONCLUSION: This seems to be the first case report in English of the cytomorphology of E oligarthrus on fine needle aspiration cytology with histopathologic confirmation.

Adolescent↗

Fine needle aspiration cytodiagnosis of clinically suspected tuberculosis in tissue enlargements.

A retrospective study of the use of fine needle aspiration (FNA) cytology to confirm a clinical suspicion of tuberculosis in tissue enlargements was performed, using 70 cases. The criteria required to make an FNA cytodiagnosis of tuberculosis were reassessed, and the sensitivity and predictive value of cytology for diagnosing such aspirates was determined. All but 2 of the 70 aspirates contained adequate cellularity. The adequate samples were diagnosed as 40 cases of caseating tuberculosis, 11 cases of noncaseating tuberculosis and 17 cases of acute necrotizing granulomatous inflammation suspicious for tuberculosis. Subsequent histologic study verified the cytologic diagnosis in 27 of 27 biopsied caseating lesions, 4 of 7 biopsied noncaseating cases and 5 of 8 necrotizing cases. The six cases with a false-positive cytodiagnosis of tuberculosis were histologically diagnosed as one Lennert's lymphoma, two reactive lymph nodes and three necrotizing metastatic carcinomas. The sensitivity of FNA cytology for the diagnosis of tuberculosis was 100%, with the predictive value of a positive result being 88%. The findings in this study emphasize that all criteria for the diagnosis of tuberculosis in FNA samples must be utilized and that particular caution should be exercised in making a diagnosis of acute necrotizing tuberculosis.

Biopsy, Needle↗

Ultrasonically guided fine needle aspiration of the parathyroid. A report of two cases.

Two cases of parathyroid adenoma were diagnosed with ultrasound-guided fine needle aspiration. Both patients were clinically suspected of having features of primary hyperparathyroidism. On aspiration, one had an associated cystic change with golden brown fluid and the other a markedly cellular aspirate. The cells aspirated were differentiated from thyroid epithelial cells.

Adenoma↗